Results 251 to 260 of about 151,999 (312)

Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease

Experimental Physiology, Volume 111, Issue 6, Page 2787-2804, 1 June 2026.
Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi, David Wang, William W. Stringer, Richard Casaburi, Harry B. Rossiter   +4 more
wiley   +1 more source

Modality-specific effects of structured exercise on immunometabolic biomarkers in postmenopausal obesity: a Bayesian network meta-analysis. [PDF]

Front Immunol
Huang G, Wang W, Jiang H, Zhou B, Zhang J, Chen Z, Zhao P.   +6 more
europepmc   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

LEPR Contributes to Lung Squamous Cell Carcinoma: Insights From Mendelian Randomization and Experimental Studies. [PDF]

Cancer Inform
Hu W, Wu G, Lin Y, Li S, Lin Z, Chen Y, Cheng Z, Zeng J, Yang Z, Wang Y.   +9 more
europepmc   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

Experimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer, Dena Lin, Alec Hanshew, Jackson Stewart, Steven Ball, Christa Lilly, Saina S. Prabhu, Kate Karelina, Eric E. Kelley, Randy W. Bryner, Dharendra Thapa, Paul D. Chantler   +11 more
wiley   +1 more source

Marrow leptin-LEPR signaling rewires mitochondrial oxidative metabolism to confer chemoresistance in acute myeloid leukemia. [PDF]

Cell Death Dis
Liao X, Dai W, Xu X, Cai D, Tan M, Wang Z, Huang Y, Hou D, Liu J, Wang L, Wang J, Wang X, Zhang S, Lin X, Huang H.   +14 more
europepmc   +1 more source

The leptin fragment Lep116-130 attenuates hedonic consumption and sucrose-seeking in mice. [PDF]

Front Pharmacol
Ramírez-Romero R, Jiménez Y, Kerr B, Dinamarca-Villarroel L, Robles A, Llanos P, Montaña P, Cortés V, Perez-Leighton C, Baudrand R.   +9 more
europepmc   +1 more source

REP-1 deficiency induces aberrant mitochondrial metabolic rewiring from glycolysis to lipid oxidation in CHM disease. [PDF]

Cell Death Dis
Buonocore S, Giamundo G, Barone C, Carratù I, Trinchese G, Vitale GA, Fasciolo G, Ziaco M, Venditti P, Fontana A, Mollica MP, Antonini D, Conte I.   +12 more
europepmc   +1 more source

Role of certain adipokines in the pathophysiology of hypertension. [PDF]

Front Physiol
Yilmaz A, Obay BD, Ekinci A.
europepmc   +1 more source