Results 101 to 110 of about 1,272,125 (151)

Obesity, Leptin and Leptin Receptors

Gene, Cell and Tissue, 2016
Saeed Khosropour, Maryam Shojaee, Peyman Lotfi   +2 more
openaire   +1 more source

AN ECONOMIC ANALYSIS OF GENETIC INFORMATION: LEPTIN GENOTYPING IN FED CATTLE [PDF]

The use of genetic knowledge is widespread in crop production but is just recently being utilized in livestock production. This study investigates the economic value to feedlots of a polymorphism in the bovine leptin gene.
Bullinger, Jared R., Bauer, Marc L., Berg, Paul T., DeVuyst, Eric A., Larson, Daniel M.   +4 more
core  

Metabolic and serotonergic modulation of hypothalamic arcuate nucleus neurones in vitro [PDF]

1. The effects of glucose on the electrophysiological properties of rat hypothalamic arcuate nucleus (ARC) neurones were investigated. Neurones were recorded in 10 mM (hyperglycaemic) and 2 mM (euglycaemic) glucose-containing aCSF.
Saker, Louise
core  

Interaction between leptin and leptin receptor in gastric carcinoma: Gene ontology analysis

, 2007
Gastric carcinoma is a rare but important malignancy. The link between leptin, a cytokine that is elevated in obese individuals, and cancer development has been proposed.
Wiwanitkit,V.
core  

Leptin and autoimmunity: role of leptin in the modulation of immune response during Experimental Autoimmune Encephalomyelitis [PDF]

, 2008
Procaccini, Claudio
core   +1 more source

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Leptin Receptor and Leukemia

Leukemia and Lymphoma, 2000
The receptor for leptin, the gene product of the obese gene, is expressed in hematopoietic stem cells. Leptin stimulates normal myeloid and erythroid development, and is secreted from bone marrow adipocytes, which occupy most of the marrow cavity in humans.
Masayuki Hino, Takahisa Yamane, Noriyuki Tatsumi   +2 more
exaly   +3 more sources

Localization of Leptin Binding Domain in the Leptin Receptor

Molecular Pharmacology, 1998
The leptin receptor is a member of the class I cytokine receptor family and is involved in the control of appetite and body weight. The predicted amino acid sequence of the extracellular region of the cloned leptin receptor differs from that of many other cytokine receptors in that it contains two homologous segments representing potential ligand ...
R R Huang, J E Krause, T M Fong
exaly   +3 more sources

Serum leptin levels, skin leptin and leptin receptor expression in psoriasis

British Journal of Dermatology, 2008
Recent studies support the relation of psoriasis with obesity and cardiovascular disease. Leptin, a peptide hormone secreted predominantly from adipose tissue, is involved in the regulation of energy intake and expenditure. Recently, it has been shown to have several immunological effects including induction of proinflammatory cytokine production.To ...
Aydin Sav, Aysin Tülünay Virlan
exaly   +4 more sources

Atomistic mechanism of leptin and leptin-receptor association

Journal of Biomolecular Structure and Dynamics, 2022
The leptin-leptin receptor complex is at the very core of energy homeostasis and immune system regulation, among many other functions. In this work, we built homology models of leptin and the leptin binding domain (LBD) of the receptor from humans and mice.
Marisol López-Hidalgo, Luis A. Caro-Gómez, Rubí Romo-Rodríguez, Leonardo D. Herrera-Zuñiga, Maricruz Anaya-Reyes, Jorge L. Rosas-Trigueros, Claudia G. Benítez-Cardoza   +6 more
openaire   +2 more sources

Leptin and its receptors

Journal of Chemical Neuroanatomy, 2014
Leptin is mainly produced in the white adipose tissue before being secreted into the blood and transported across the blood-brain barrier. Leptin binds to a specific receptor (LepR) that has numerous subtypes (LepRa, LepRb, LepRc, LepRd, LepRe, and LepRf).
Nobuhiro, Wada, Satoshi, Hirako, Fumiko, Takenoya, Haruaki, Kageyama, Mai, Okabe, Seiji, Shioda   +5 more
openaire   +2 more sources