Results 81 to 90 of about 1,272,125 (151)

Association of Leptin and Leptin receptor Gene polymorphisms with Insulin resistance in pregnant women: A cross-sectional study [version 3; peer review: 3 approved]

F1000Research
Introduction Leptin, along with its receptor, are linked with mechanisms affecting a diverse array of pregnancy-specific pathologies that include gestational diabetes and intrauterine growth restriction.
Usha Adiga, Tirthal Rai, Nandit Banawalikar   +2 more
doaj   +1 more source

Lipoprotein receptor LRP1 regulates leptin signaling and energy homeostasis in the adult central nervous system.

PLoS Biology, 2011
Obesity is a growing epidemic characterized by excess fat storage in adipocytes. Although lipoprotein receptors play important roles in lipid uptake, their role in controlling food intake and obesity is not known.
Qiang Liu, Juan Zhang, Celina Zerbinatti, Yan Zhan, Benedict J Kolber, Joachim Herz, Louis J Muglia, Guojun Bu   +7 more
doaj   +1 more source

Leptin Signaling and Action in Birds

The Journal of Poultry Science, 2008
The discovery of leptin has led to an understanding of the regulation of energy expenditure and food intake in a number of vertebrates. Leptin is also implicated in diverse physiological functions.
Takeshi Ohkubo, Hiromi Adachi
doaj   +1 more source

Characterization and remodeling of the vasculature in human adipose tissue [PDF]

, 2007
Die Ursache von Adipositas liegt im übermäßigen Wachstum von Fettgewebe, welches hauptsächlich aus Fettzellen, den Adipozyten, besteht. Die Zellen der stroma-vaskulären Fraktion, welche Vorläuferzellen, Makrophagen und Zellen des lokalen Gefäßnetzwerks ...
Miranville, Alexandra
core  

Advances of the Relationship between Leptin System and Non-small Cell Lung Cancer

Chinese Journal of Lung Cancer, 2014
Leptin system plays an important role in lung inflammation and tumorigenesis, but the precise function in the tumormicrovironment and the prognosis value of the leptin system in lung cancer have not been fully elucidated.
Tengfei WEI, Longkun LU, Qian SHEN, Chaoping FANG   +3 more
doaj   +1 more source

Pregnancy glycaemia and cord-blood levels of insulin and leptin in Pakistani and white British mother-offspring pairs:findings from a prospective pregnancy cohort [PDF]

, 2014
AIMS/HYPOTHESIS: To determine the extent to which gestational fasting and postload levels of glucose explain differences in infant fat mass between UK-born Pakistani and white British infants.METHODS: Analyses were undertaken in a prospective pregnancy ...
Bhopal, Raj S, Bhopal, RS, Tuffnell, Derek, Bhopal, Raj S., West, J, Nelson, Scott M., Freeman, Dilys J., Sattar, N, Fairley, L, Freeman, DJ, John Wright, Lawlor, Debbie A, Nelson, SM, Dilys J. Freeman, Debbie A. Lawlor, Freeman, Dilys J, Wright, John, Whitelaw, Donald C., Lesley Fairley, Whitelaw, DC, Fairley, Lesley, Sattar, Naveed, Nelson, Scott M, Jane West, Whitelaw, Donald C, Lawlor, Debbie A., Derek Tuffnell, Scott M. Nelson, Raj S. Bhopal, Donald C. Whitelaw, Naveed Sattar, Lawlor, DA, Wright, J, Tuffnell, D, West, Jane   +34 more
core   +1 more source

Gene Expression of Leptin and Long Leptin Receptor Isoform in Endometriosis: A Case-Control Study

Obstetrics and Gynecology International, 2013
In this study, leptin/BMI ratio in serum and peritoneal fluid and gene expression of leptin and long form leptin receptor (OB-RL) were assessed in eutopic and ectopic endometria of women with endometriosis and controls.
Andrea Prestes Nácul, Sheila Bunecker Lecke, Maria Isabel Edelweiss, Débora Martinho Morsch, Poli Mara Spritzer   +4 more
doaj   +1 more source

Avian leptin bound to leptin receptor.

, 2014
A) Energy minimized model of full chicken leptin receptor embedded in a lipid membrane. Amino acids colored in red are conserved amongst various avian sequences and human.
Amy Milsted (30880), Larry A. Cogburn (214991), Donald Gasper (542023), Cameron Schmidt (542022), Robert J. Duff (542024), Matthew D. Shawkey (267103), Richard L. Londraville (102559), Jeremy W. Prokop (417645), Hope C. Ball (102557), Takeshi Ohkubo (542025), Herman L. Mays Jr (542026)   +10 more
core   +1 more source

Receptor usage by the Acanthocheilonema viteae-derived immunomodulator, ES-62 [PDF]

, 2012
ES-62 is an immunomodulatory phosphorylcholine (PC)-containing glycoprotein secreted by the rodent filarial nematode Acanthocheilonema viteae. Previously, the use of knockout mice has revealed the effects of ES-62 on macrophages and dendritic cells to be
Allen, Janet, Harnett, Margaret, Goodridge, Helen, Harnett, William   +3 more
core   +2 more sources

A molecular overview of leptin in several pathological conditions

, 2023
Leptin is a 16 kDa peptide hormone that is the product of LEP (also known as OB) gene. The Leptin gene is primarily expressed in white adipocytes. Although the leptin hormone is mainly associated with the regulation of body weight and energy expenditure ...
Ceylan,M.A., Gozel,H.E.
core