Results 131 to 140 of about 2,380,940 (353)
Food Biomacromolecules, EarlyView.Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo +3 more
wiley +1 more source
Involvement of agouti-related protein, an endogenous antagonist of hypothalamic melanocortin receptor, in leptin action. [PDF]
, 1999 Ken Ebihara +12 more
openalex +1 more source
Lipid Profile and Leptin Levels in Patients with Metabolic Syndrome
Medical Laboratory Journal, 2014 Background and Objective: Metabolic syndrome called a cluster of several metabolic disorders is associated with increased risk of cardiovascular diseases.
R Esmaeili, T Hassanzadeh
doaj
A Hypothalamic Leptin-Glutamate Interaction in the Regulation of Sympathetic Nerve Activity
Neural Plasticity, 2017 Accumulated evidence indicates that obesity-induced type 2 diabetes (T2D) is associated with enhanced sympathetic activation. The present study was conducted to investigate the role for leptin-glutamate signaling within the hypothalamus in regulating ...
Hong Zheng +3 more
doaj +1 more source
Leptin and Pathological Indexes in Women with Breast Cancer
Armaghane Danesh Bimonthly Journal, 2015 Background & aim: Breast cancer is the most common cancer among women and one of the factors threatening the health of women worldwide. Leptin is a 16 kD glycoprotein hormone produced predominantly by white adipose tissue.
B Noori Alavicheh +7 more
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Homocysteine causes neuronal leptin resistance and endoplasmic reticulum stress
PLoS ONE, 2022 Abnormally high serum homocysteine levels have been associated with several disorders, including obesity, cardiovascular diseases or neurological diseases.
Arini Isnani Preninka +8 more
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Expression of Functional Leptin Receptors in Rodent Leydig Cells1 [PDF]
, 1999 Massimiliano Caprio +5 more
openalex +1 more source
Functional Antagonism between CCAAT/Enhancer Binding Protein-α and Peroxisome Proliferator-activated Receptor-γ on the Leptin Promoter [PDF]
, 1997 Anthony N. Hollenberg +8 more
openalex +1 more source
iMetaOmics, EarlyView.This narrative review uniquely addresses how gut microbiota‐derived metabolites mediate overlapping pathologies of insulin resistance, neuroinflammation, and amyloidogenesis in type 2 diabetes mellitus (T2DM) and Alzheimer's disease (AD), proposing a framework for dual therapeutic targeting.
Guangyi Xu +8 more
wiley +1 more source