Results 141 to 150 of about 73,797 (197)

Leptin Receptor Deficiency-Associated Diabetes Disrupts Lacrimal Gland Circadian Rhythms and Contributes to Dry Eye Syndrome. [PDF]

Invest Ophthalmol Vis Sci
Pei X, Ba M, Yang T, Xuan S, Huang D, Qi D, Lu D, Huang S, Li Z.   +8 more
europepmc   +1 more source

Therapeutic potential of okra (Abelmoschus esculentus) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diabetes spectrum

Experimental Physiology, EarlyView.
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari, Helia Mardani, Mohammad Amin Karimi, MohammadHossein Sahami Gilan, Helia Hemmat, Fatemeh Shoja, Nooshin Enayati Soofi, Ghazaleh Eslamian   +7 more
wiley   +1 more source

Hypoxia inducible factor-1α promotes non-small cell lung cancer progression by activating leptin receptor transcription. [PDF]

Cancer Biomark
Li Y, Chen B, Wu S, Zhong Y, Zhang Y, Wu J.   +5 more
europepmc   +1 more source

Higher body‐mass index modifies time‐resolved maternal autonomic cardiac–uterine coupling during the first stage of human labour

Experimental Physiology, EarlyView.
Abstract We investigated whether higher body mass index (BMI) modifies time‐resolved maternal autonomic control and maternal cardio‐electrohysterographic coupling (MCEC) during the first stage of labour. Seventy‐nine women were studied and, for the present analysis, grouped as Control (C; n = 41) and high BMI (HBMI; n = 38).
Carlos Gabriel Varela‐Albarrán, José Javier Reyes‐Lagos, Laura Mercedes Santiago‐Fuentes, Guadalupe Dorantes‐Méndez, Eric Alonso Abarca‐Castro, Paula Romina Soria, Araceli Espinosa‐Guerrero   +6 more
wiley   +1 more source

Impact of the leptin receptor gene on pig performance and quality traits. [PDF]

Sci Rep
Suárez-Mesa R, Ros-Freixedes R, Pena RN, Reixach J, Estany J.   +4 more
europepmc   +1 more source

Skeletal muscle‐specific myostatin overexpression promotes muscle oxidative capacity and fatigue resistance in transgenic mice

Experimental Physiology, EarlyView.
Abstract In addition to controlling muscle mass, myostatin may support oxidative metabolism and endurance. Loss of function through gene knockout or post‐natal blockade generally lowers muscle oxidative capacity and increases fatigability. These observations imply that myostatin activation could promote a more oxidative and less fatigable muscle ...
Andy V. Khamoui, Andrea Abraham, Janos Porszasz, Istvan Kovanecz, Silvana Constantinescu, Harry B. Rossiter, Suzanne Reisz‐Porszasz   +6 more
wiley   +1 more source

Effect of Leptin Receptor Q223R Polymorphism on Clostridioides difficile Infection-Induced Macrophage Migration Inhibitory Factor Production. [PDF]

J Infect Dis
Mathew AM, Huber A, Sous RD, Weghorn KN, Powers-Fletcher MV, Jose S, Madan R.   +6 more
europepmc   +1 more source

Independent and synergistic effects of maternal and paternal obesogenic diets on offspring early‐life outcomes in the rat

Experimental Physiology, EarlyView.
Abstract Independent effects of maternal obesogenic diets on offspring outcomes are acknowledged, but data on paternal and combined maternal–paternal obesity remain limited. We investigated independent and combined maternal–paternal effects of an obesogenic (OB) high‐fat, high‐sugar diet on offspring outcomes.
Khurram Jahangir Toor, Mehwish Abbasi, Swetha Muralidharan, Elisa Weiss, Elwyn C. Firth, Anna P. Ponnampalam, David S. Musson, Mark H. Vickers, Benjamin B. Albert   +8 more
wiley   +1 more source

Prime editing-mediated correction of the leptin receptor in muscle cells of db/db mice. [PDF]

Biotechnol J
Lee KE, Xu Y, Geng B, Kim J, Kellon N, He Z, Zhang Z, Li D, Gouchoe DA, Zhu H.   +9 more
europepmc   +1 more source

Sex‐specific metabolic responses to glucagon receptor agonism and modulation of the FGF21‐glucagon axis in female mice

The Journal of Physiology, EarlyView.
Abstract figure legend Therapies targeting the glucagon receptor are being explored for obesity treatment, yet most preclinical studies remain male biased. In this study, Merrild and Johansen et al. show that in diet‐induced obese wild‐type mice a long‐acting glucagon analogue (LA‐Gcg) elicits sexually dimorphic effects on weight loss, food intake ...
Christoffer Merrild, Valdemar Brimnes Ingemann Johansen, Christoffer Clemmensen, Pablo Ranea‐Robles   +3 more
wiley   +1 more source