Results 161 to 170 of about 73,797 (197)

ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation. [PDF]

open access: yesProc Natl Acad Sci U S A
Hu H   +20 more
europepmc   +1 more source

Leptin receptor neurons in the ventral premammillary nucleus modulate emotion-induced insomnia. [PDF]

open access: yesCell Discov
Yuan XS   +9 more
europepmc   +1 more source

Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): Results from a first-in-human phase I study. [PDF]

open access: yesClin Transl Sci
Gewitz A   +10 more
europepmc   +1 more source

Leptin and Leptin Receptor Polymorphisms in Infants and Their Parents: Correlation with Preterm Birth. [PDF]

open access: yesGenes (Basel)
Savino F   +7 more
europepmc   +1 more source

Atomistic mechanism of leptin and leptin-receptor association

Journal of Biomolecular Structure and Dynamics, 2022
The leptin-leptin receptor complex is at the very core of energy homeostasis and immune system regulation, among many other functions. In this work, we built homology models of leptin and the leptin binding domain (LBD) of the receptor from humans and mice.
Marisol López-Hidalgo   +6 more
openaire   +2 more sources

The soluble leptin receptor

Best Practice & Research Clinical Endocrinology & Metabolism, 2015
The adipokine leptin realizes signal transduction via four different leptin receptor (OB-R) isoforms. The amount of functionally active OB-R, however, is affected by constitutive shedding of the extracellular domain. The product of the cleavage process, the so-called soluble leptin receptor (sOB-R), is the main binding protein for leptin in human blood
Michael, Schaab, Juergen, Kratzsch
openaire   +2 more sources

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