ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation. [PDF]
Hu H +20 more
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Leptin receptor neurons in the ventral premammillary nucleus modulate emotion-induced insomnia. [PDF]
Yuan XS +9 more
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Effect of <i>Aeromonas hydrophila</i> infection on leptin receptor overlapping transcript expression in <i>Rana amurensis</i>. [PDF]
Sun Y +6 more
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Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice. [PDF]
Sáenz de Miera C +4 more
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Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): Results from a first-in-human phase I study. [PDF]
Gewitz A +10 more
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Leptin and Leptin Receptor Polymorphisms in Infants and Their Parents: Correlation with Preterm Birth. [PDF]
Savino F +7 more
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Atomistic mechanism of leptin and leptin-receptor association
Journal of Biomolecular Structure and Dynamics, 2022The leptin-leptin receptor complex is at the very core of energy homeostasis and immune system regulation, among many other functions. In this work, we built homology models of leptin and the leptin binding domain (LBD) of the receptor from humans and mice.
Marisol López-Hidalgo +6 more
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The adipokine leptin realizes signal transduction via four different leptin receptor (OB-R) isoforms. The amount of functionally active OB-R, however, is affected by constitutive shedding of the extracellular domain. The product of the cleavage process, the so-called soluble leptin receptor (sOB-R), is the main binding protein for leptin in human blood
Michael, Schaab, Juergen, Kratzsch
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