Results 171 to 180 of about 75,788 (264)

Leptin and leptin receptor gene polymorphisms and depression treatment response. [PDF]

Acta Neuropsychiatr
Tavast IM, Solismaa A, Lyytikäinen LP, Mononen N, Moilanen E, Hämäläinen M, Lehtimäki T, Kampman O.   +7 more
europepmc   +1 more source

Precision or Paradox? AI‐Driven Adiposity Imaging in Women With Overweight and Obesity: A Systematic Review and Meta‐Analysis

Obesity Reviews, EarlyView.
ABSTRACT Artificial intelligence (AI) enables automated, high‐throughput adiposity quantification, offering refined risk stratification for women with overweight and obesity. We systematically reviewed and meta‐analyzed studies evaluating AI‐based segmentation of visceral, subcutaneous, and total fat in adult women populations (BMI: 25–29.9 and ≥ 30 kg/
Asefa Adimasu Taddese, Bjorn T. Tam
wiley   +1 more source

Osteolectin/CLEC11A‐Related Signaling Molecules in Periodontitis and Peri‐Implantitis

Oral Diseases, EarlyView.
ABSTRACT Objective Periodontal and peri‐implant tissues differ histologically and biomechanically, which may be reflected in local osteogenic and mechanosensitive signaling. This exploratory cross‐sectional study aimed to compare expression profiles of Osteolectin (CLEC11A) and related signaling molecules across periodontal health, peri‐implant health,
Gözde Işıker Kara, Feyzanur Caldiran, Hatice Balci Yuce, Busenur Sahin, Ercan Cacan   +4 more
wiley   +1 more source

Cinnamaldehyde Inhibits Leptin-Induced MMP-1 by Modulating Leptin Receptor/STAT3 and Blocking RhoA/NF-κB Pathways in Human Intervertebral Disc Stem Cells. [PDF]

Int J Mol Sci
Hua KF, Yu HC, Hsu HT.
europepmc   +1 more source

Setmelanotide in Bardet‐Biedl Syndrome: A Case Report

Pediatric Dermatology, EarlyView.
ABSTRACT Setmelanotide is a melanocortin‐4‐receptor agonist used for the treatment of hyperphagia in the genetic obesity syndrome Bardet‐Biedl. Presented is a case of diffuse hyperpigmentation in a patient treated with setmelanotide, which represents the most common side effect of this medication.
Shelby Smith, Eric Sanfilippo, Lara Wine Lee   +2 more
wiley   +1 more source

Divergence of Leptin Receptor and Interleukin-6 Receptor Subunit b in Early Vertebrate Evolution and Physiological Insights from the Sea Lamprey. [PDF]

Mol Biol Evol
Gong N, Barany A, Norstog JL, Larhammar D, Björnsson BT, Regish AM, McCormick SD, Sheridan MA.   +7 more
europepmc   +1 more source

Shared molecular framework and bidirectional effects of osteoporosis on periodontal disease and dental implant therapy in the elderly

Periodontology 2000, EarlyView.
Abstract Objectives This review synthesizes evidence regarding the prevalence, epidemiological associations, and mechanistic pathways between osteoporosis, periodontal disease, and dental implant therapy. Materials and Methods A literature review was conducted to identify studies focused on: osteoporosis, periodontal disease, and dental implants ...
Samin Sirous, Jaclyn C. Chalmers, Pin‐Ying Li, Yumna Subhani, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

KCNB1-Leptin receptor complexes couple electric and endocrine function in the melanocortin neurons of the hypothalamus. [PDF]

FASEB J
Forzisi-Kathera-Ibarra E, Jo C, Castillo L, Gaur A, Lad P, Bortolami A, Roser C, Venkateswaran S, Dutto S, Selby M, Sampath H, Pan PY, Sesti F.   +12 more
europepmc   +1 more source

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, EarlyView.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source