Results 241 to 250 of about 76,631 (314)

Expression Patterns of Leptin, Leptin Receptor, Kiss1, and HOTAIR Genes in Blood and Semen of Infertile Males with Oligospermia. [PDF]

open access: yesRep Biochem Mol Biol
Khademi F   +6 more
europepmc   +1 more source

Ageing reveals the latent effects of early life stress on respiratory and metabolic function in female rats: Novel insights into the sex‐specific origins of sleep apnoea

open access: yesExperimental Physiology, EarlyView.
Abstract Sleep apnoea (SA) is ∼2 times more prevalent in men than women. However, this changes at menopause as the occurrence of SA increases and matches that of men. Menopause is a natural process, but it remains unclear why SA emerges only in a subpopulation of ageing women.
Danuzia Ambrozio‐Marques   +4 more
wiley   +1 more source

Evaluation of metabolism‐related molecules in rat model of autism spectrum disorders

open access: yesExperimental Physiology, EarlyView.
Abstract Autism spectrum disorders (ASD) are neurodevelopmental pathologies. Investigating both sexes is crucial for understanding sex‐specific manifestations of ASD. This study aims to examine ASD‐like behaviours and metabolic alterations in male and female rats prenatally exposed to valproic acid (VPA).
Süeda Tunçak   +3 more
wiley   +1 more source

Association of leptin −2548G/A and leptin receptor Q223R polymorphisms with increased risk for oral cancer

open access: green, 2008
Christos Yapijakis   +9 more
openalex   +2 more sources

The role of agomelatine in appetite regulation and body weight in rats

open access: yesExperimental Physiology, EarlyView.
Abstract The hypothalamic nuclei play a central role in the synthesis of anorexigenic and orexigenic neuropeptides, which are regulated by peripheral hormones, like leptin and ghrelin. Melatonergic receptors (MT1/MT2) are prominently expressed in the arcuate nucleus of the hypothalamus – an essential hub for appetite control – and in peripheral ...
Engin Korkmaz   +3 more
wiley   +1 more source

Prevention and treatment of peri-implant fibrosis by functionally inhibiting skeletal cells expressing the leptin receptor. [PDF]

open access: yesNat Biomed Eng
Suhardi VJ   +12 more
europepmc   +1 more source

Adipose tissue‐derived small extracellular vesicles and blood–brain barrier function in adults with overweight and obesity

open access: yesExperimental Physiology, EarlyView.
Abstract Obesity is associated with adverse changes in brain structure and function, in part, through crosstalk between adipose tissue (AT) and the brain. AT releases small extracellular vesicles (sEV) that can cross the blood–brain barrier (BBB) and modulate multiple pathophysiological pathways, including BBB function; however, this has never been ...
Shalini Mishra   +6 more
wiley   +1 more source

Impact of long‐term maternal high‐fat, high‐sugar feeding on gastric vagal afferent responses and feeding behaviour in mouse offspring

open access: yesExperimental Physiology, EarlyView.
Abstract Poor maternal nutrition and excessive gestational weight gain predict future development of obesity in offspring. Preclinically, maternal obesity induced by a high‐fat, high‐sugar diet (HFHSD) induces hyperphagia and obesity in offspring. We hypothesized that this might, in part, reflect reduced peripheral gastric vagal afferent (GVA) satiety ...
Georgia S. Clarke   +7 more
wiley   +1 more source

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

open access: yesExperimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer   +11 more
wiley   +1 more source

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