Results 241 to 250 of about 138,647 (310)

Sex‐dependent effects of a high‐fat diet‐induced obesity model on cerebrovascular health and brain metabolism

open access: yesExperimental Physiology, EarlyView.
Abstract Mid‐life obesity is a major risk factor for neurodegenerative diseases, with mitochondrial and cerebrovascular dysfunction considered key mediators. Lysine acetylation is a reversible post‐translational modification that regulates several mitochondrial metabolic and biochemical processes.
Nicole N. Eminhizer   +11 more
wiley   +1 more source

Therapeutic potential of okra (Abelmoschus esculentus) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diabetes spectrum

open access: yesExperimental Physiology, EarlyView.
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari   +7 more
wiley   +1 more source

Leptin receptor neurons in the ventral premammillary nucleus modulate emotion-induced insomnia. [PDF]

open access: yesCell Discov
Yuan XS   +9 more
europepmc   +1 more source

Higher body‐mass index modifies time‐resolved maternal autonomic cardiac–uterine coupling during the first stage of human labour

open access: yesExperimental Physiology, EarlyView.
Abstract We investigated whether higher body mass index (BMI) modifies time‐resolved maternal autonomic control and maternal cardio‐electrohysterographic coupling (MCEC) during the first stage of labour. Seventy‐nine women were studied and, for the present analysis, grouped as Control (C; n = 41) and high BMI (HBMI; n = 38).
Carlos Gabriel Varela‐Albarrán   +6 more
wiley   +1 more source

ANGPTL4 binds to the leptin receptor to regulate ectopic bone formation. [PDF]

open access: yesProc Natl Acad Sci U S A
Hu H   +20 more
europepmc   +1 more source

Early adversity and the comorbidity between metabolic disease and psychopathology

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas   +1 more
wiley   +1 more source

Impaired angiogenesis in gestational diabetes is linked to succinate/SUCNR1 axis dysregulation in late gestation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Gestational Diabetes Mellitus (GDM) impacts on succinate metabolism and angiogenesis in the umbilical cord endothelium. (Left Panel) Succinate levels increase in both maternal and fetal circulation at delivery, with higher concentrations observed in GDM pregnancies compared to controls during late gestation.
Sergiy Klid   +13 more
wiley   +1 more source

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