Results 51 to 60 of about 11,910 (159)

Visual loss as the initial manifestation of an ignored disseminated prostate cancer: A case report

American Journal of Ophthalmology Case Reports, 2022
Purpose: To present a rare case of advanced disseminated prostate cancer with bilateral visual loss as the initial manifestation of the disease. Observations: A 55-year-old man referring progressive visual blurring for the last 6 months and painless ...
Alejandra B. Miranda, Carla D. Guantay, Evangelina Espósito, Julio A. Urrets-Zavalía   +3 more
doaj   +1 more source

Dysphagia and anorexia as presentations of leptomeningeal carcinomatosis [PDF]

BMJ Case Reports, 2016
A 61-year-old woman presented to the emergency department, with a 4-day history of isolated oropharyngeal dysphagia associated with anorexia and weight loss over the previous 4 weeks. She had no other focal neurological symptoms and no deficits on examination.
Rohit, Aiyer, Ester, Engelman, Wei, Xue, Edward, Yu   +3 more
openaire   +2 more sources

Efficacy and safety of camrelizumab combined with apatinib as second‐line and beyond treatment for advanced combined hepatocellular‐cholangiocarcinoma

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Camrelizumab plus apatinib demonstrated promising efficacy (ORR 20.0%, DCR 72.0%, mOS 12.5 months, mPFS 4 months) and excellent tolerability (no grade ≥3 TRAEs) as second‐line and beyond therapy for advanced cHCC‐CCA, with CA19‐9 dynamics identified as a potential early surrogate biomarker for treatment response.
Haiyun Geng, Fang Dai, Kuimin Mei, Mengran Cao, Haiqing Hua, Xinlei Gong   +5 more
wiley   +1 more source

A Rare Case of Suspected Immune‐Related Encephalopathy Following Pembrolizumab Plus Lenvatinib Therapy for Renal Cell Carcinoma

IJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Immune‐related encephalopathy is a rare neurological adverse event associated with immune checkpoint inhibitors. Neuroimaging and cerebrospinal fluid findings are often unremarkable, making the diagnosis challenging. Case Presentation A 70‐year‐old man with advanced clear cell renal cell carcinoma (RCC) was considered unresectable
Yuina Nagao, Kyotaro Fukuta, Yuichiro Atagi, Keisuke Ozaki, Takeshi Nakashima, Kenta Sato, Ryoichi Nakanishi, Hirofumi Izaki, Junya Furukawa   +8 more
wiley   +1 more source

Stroke associated with microvascular tumoral infiltration in a patient with metastatic breast cancer

Radiology Case Reports
Leptomeningeal carcinomatosis is a form of advanced metastatic disease conferring poor prognosis, most commonly associated with melanoma, small cell lung cancer, and breast cancer.
Joshua Mangerel, MD, Andres Rodriguez-Sein, MD, Daniel Masri, MD   +2 more
doaj   +1 more source

Craniospinal irradiation in the treatment of chemotherapy refractory leptomeningeal metastasis from breast cancer: A case report

Cancer Reports, 2022
Background Leptomeningeal carcinomatosis is a relatively uncommon complication of solid tumors that is associated with significant morbidity and mortality.
Daniel Tesolin, Dimitrios Vergidis, Kevin Ramchandar   +2 more
doaj   +1 more source

Leptomeningeal carcinomatosis in a patient with recurrent unresectable squamous cell carcinoma of the retromolar trigone—a brief report

Journal of the Egyptian National Cancer Institute, 2022
Background The reported incidence of leptomeningeal carcinomatosis is 3–8% in patients with solid tumours. More commonly, it has been described in the setting of advanced cancers of the lung, breast and malignant melanoma. Case presentation A 50-year-old
Jhansi Pattanaik, Varshu Goel, Priyanka Sehrawat, Ruchi Rathore, Rajesh Kumar Singh, Ajay Garg, Ahitagni Biswas   +6 more
doaj   +1 more source

Effects of Biological Sex and Age on Cerebrospinal Fluid Markers—A Retrospective Observational Study

Annals of Clinical and Translational Neurology, Volume 13, Issue 6, Page 1222-1235, June 2026.
ABSTRACT Objective Cerebrospinal fluid (CSF) analysis is a key diagnostic tool for neurological diseases. To date, only a few studies have investigated in larger cohorts the effect of age and biological sex on diagnostic markers extracted from CSF. Methods For this retrospective observational study, 4163 CSF findings (2012–2020) were evaluated.
Isabel‐Sophie Hafer, Simon Faissner, Ralf Gold, Aiden Haghikia   +3 more
wiley   +1 more source

Complete Eye Ophthalmoplegia: the unusual initial presentation of Leptomeningeal Carcinomatosis

, 2019
Ophthalmoplegia is a paralysis or weakness of extraocular muscles that have a variety of different etiologies including and not limited to Leptomeningeal Carcinomatosis (LC).
Ateeq Mubarik, Mohammad Eid, Salman Muddassir, Ali Vaziri, Abdulmagid Eddib, Lakshpaul Chauhan   +5 more
core   +1 more source

Quantification of Vascular Burden on Cranial Vessel Wall Magnetic Resonance Imaging and Ophthalmic Complications in Giant Cell Arteritis

ACR Open Rheumatology, Volume 8, Issue 5, May 2026.
Objective There is a need for measures of disease severity for giant cell arteritis (GCA), which may enable identification of high‐risk subgroups (eg, ophthalmic complications) and individualized approaches to therapy. We derived a continuous score using data from cranial vessel wall magnetic resonance imaging (VW‐MRI) to quantify vascular burden in ...
David L. Yang, Quy Cao, Fang Liu, Tara McWilliams, Ryan Rebello, Madhura A. Tamhankar, Shubhasree Banerjee, Rui Liang, Robert M. Kurtz, Joshua F. Baker, Naomi Amudala, Zhaoyang Fan, Jae W. Song, Peter A. Merkel, Jeffrey Morris, Rennie L. Rhee   +15 more
wiley   +1 more source