Results 61 to 70 of about 11,910 (159)

Reduction in Circulating Tumor Cell Count following Therapy with nab®-Paclitaxel plus Carboplatin in a Patient with Leptomeningeal Carcinomatosis from Breast Cancer

Case Reports in Oncology, 2012
This case study reports on a 56-year-old woman with breast adenocarcinoma and leptomeningeal metastases. After initial chemotherapy with a dose-dense regimen of doxorubicin/cyclophosphamide followed by 3 cycles of docetaxel (100 mg/m2), a lumpectomy was ...
Andrea Stebel
doaj   +1 more source

Leptomeningeal carcinomatosis in a patient with gallbladder carcinoma

Journal of Cytology, 2017
Carcinomatous meningitis is a rare manifestation of malignancy. It is increasingly being recognized in lung carcinoma, breast carcinoma, melanomas, gastrointestinal malignancies, lymphomas, and leukemia and it is almost never seen in gallbladder malignancies.
Nisha Jose, Harsha Teja Perla, Ramya Iyadurai, Geeta Chacko   +3 more
openaire   +3 more sources

Rate of Hearing Loss in Platinum‐Naïve Patients Receiving Immune Checkpoint Inhibitors

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 5, Page 1289-1297, May 2026.
Abstract Objective Hearing loss from immune checkpoint inhibitors (ICIs) has been documented in case reports and case series. We present the largest retrospective study investigating the rate of ICI‐related ototoxicity in a monitored cohort of platinum‐naïve patients. Study Design Retrospective cohort study. Setting Tertiary‐care center.
Kaitlyn A. Brooks, Christopher G. Gidley, Olivia Grimley, Catherine Wang, Shirin Jivani, Dianna Roberts, Aung Naing, Jack Phan, Katherine Hutcheson, Xin Wang, Paul W. Gidley, Marc‐Elie Nader   +11 more
wiley   +1 more source

Therapeutic Strategies to Overcome Payload Resistance of Trastuzumab Deruxtecan in HER2‐Positive Cancers

Cancer Science, Volume 117, Issue 4, Page 996-1009, April 2026.
Overexpression of ABC transporters, especially ABCG2 and ABCB1, mediates acquired resistance to T‐DXd in HER2‐positive cancers. Inhibition of these transporters restored T‐DXd efficacy, highlighting efflux‐mediated resistance as a potential therapeutic target. ABSTRACT Antibody–drug conjugates (ADCs) are emerging as a promising class of targeted cancer
Yuya Murase, Shigeki Nanjo, Sachiko Arai, Sota Kondo, Hayato Koba, Yifeng Liu, Koji Fukuda, Shigeki Sato, Jun Kinoshita, Noriyuki Inaki, Tsukasa Ueda, Shunichi Nomura, Yuichi Tambo, Takahiro Shimizu, Masafumi Horie, Daichi Maeda, Richard W. Wong, Kazuyoshi Hosomichi, Takafumi Kobayashi, Satoshi Watanabe, Kenta Yamamura, Noriyuki Ohkura, Miki Abo, Seiji Yano   +23 more
wiley   +1 more source

Neurological symptoms of leptomeningeal carcinomatosis as the primary manifestation of an adenocarcinoma of the nasal cavity and sinus: a case report and literature review

B-ENT, 2014
Neurological symptoms of leptomeningeal carcinomatosis as the primary manifestation of an adenocarcinoma of the nasal cavity and sinus: a case report and literature review. Carcinomas of the nose and paranasal sinuses are rare solid head and neck tumours.
F. Bast, T. Schrom
doaj   +2 more sources

The diagnostic and therapeutic management of leptomeningeal carcinomatosis

Annals of Oncology, 2004
The infiltration of the leptomeninges by malignant cells is not an uncommon complication of cancer and is called carcinomatous meningitis or leptomeningeal carcinomatosis (LC). Carcinomatous meningitis arises from either solid tumours or haematological malignancies.
Pavlidis, Nicholas, Pavlidis, Nicholas
openaire   +4 more sources

Identification of BRAF V600E Mutation in Cerebrospinal Fluid Aids in Diagnosing Leptomeningeal Carcinomatosis Arising From Pleomorphic Xanthoastrocytoma: A Case Report

Cancer Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Pleomorphic xanthoastrocytomas (PXAs) are rare primary central nervous system (CNS) tumors that appear heterogeneous on imaging and histology and typically cause headaches or seizures on initial presentation. Alongside high rates of favorable prognosis after surgical excision exist similarly high rates of recurrence.
Randy S. D'Amico, Patricia Avancena, Alon Kashanian, Rosivel Galvez, Deborah Gruber, Sami Saba, Avraham Zlochower, Manju Harshan, Morana Vojnic   +8 more
wiley   +1 more source

Triple Negative Breast Cancer With Choroidal Metastasis Responsive to Sacituzumab Govitecan and Radiation Therapy

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Orbital metastases are rare in patients with breast cancer. However, medical management of orbital metastases is limited by the inability of treatment options to penetrate the blood‐brain barrier. In patients with triple negative breast cancer (TNBC), these treatment options are further limited.
Nellie Nafissi, Aditya Mahadevan, Elaine Chiao, Nejina Rijal, Ritesh Parajuli   +4 more
wiley   +1 more source

SUBDUE‐3: SUB‐urothelial DUrvalumab‐89zirconium injEction; a phase 0 biodistribution study protocol

BJU International, Volume 138, Issue S2, Page S26-S29, July 2026.
Kevin G. Keane, Richard Gauci, Roslyn J. Francis, Andrew M. Scott, Cynthia Hawks, Andrisha‐Jade Inderjeeth, Ian D. Davis, Jayne Lim, Andrew Redfern, Dickon Hayne   +9 more
wiley   +1 more source

Bilateral Vocal Cord Paralysis Following Influenza A: Case Report

Clinical Case Reports, Volume 14, Issue 1, January 2026.
Flexible nasal endoscopy demonstrating bilateral vocal cord paralysis (BVCP) in the paramedian position. The left image demonstrates a glottic gap between the vocal cords (white arrows) in the maximally adducted position (patient saying “eeee”). Under normal circumstances the vocal cords should be touching with no glottic gap. The right image shows his
Dan H. V. Tran, Xiang Lay, Winston Cheung, Blake Lindsay, Benjamin Worrall, Sarika Suresh, Arun Aggarwal, Mark Kol, Atul Wagh, Rosalba Cross, Asim Shah   +10 more
wiley   +1 more source