Results 91 to 100 of about 5,255,382 (240)

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

Clinical Insights into Neurosyphilis Patients with Leptomeningeal Enhancement of Spinal Cord [PDF]

Wenjing Zhang,1,2,* Xiaoyang Ma,1,2,* Kaiyu Qin,1,2 Cheng Kou,1,2 Canglin Song,1,2 Dongmei Xu1,2 1National Center for Infectious Disease, Beijing Ditan Hospital Capital Medical University, Beijing, People’s Republic of China; 2Department of ...
Zhang W, Kou C, Qin K, Ma X, Xu D, Song C   +5 more
core  

Case Report: Leptomeningeal Metastases Mistaken Meningitis

, 2017
In this case report 52 years old woman having severe headache for two weeks, nausea, vomiting and intolerence to light has been reported. A year ago she was diagnosed as breast cancer; che-motherapy and radiotherapy treatment has finished 6 months ago ...
Zehra Karacaer, Gonca Fidan, Gülden Yılmaz, Cumhur Artuk   +3 more
core   +1 more source

Primary diffuse leptomeningeal gliosarcomatosis [PDF]

, 2015
Primary diffuse leptomeningeal gliomatosis (PDLG) is a rare condition with a fatal outcome, characterized by diffuse infiltration of the leptomeninges by neoplastic glial cells without evidence of primary tumor in the brain or spinal cord parenchyma.
김세훈, 강석구, 장종희, 김의현   +3 more
core   +1 more source

Response of Leptomeningeal Metastases in EGFR-Mutated Non-Small-Cell Lung Cancer to Afatinib in the Absence of Radiotherapy

Case Reports in Oncological Medicine, 2019
Palliative radiotherapy is currently the medical standard of care for non-small-cell lung cancer (NSCLC) patients with symptomatic CNS and leptomeningeal disease.
Néstor Llinás-Quintero, David González-Hoyos, Andrés Yepes, Diego A. Herrera, Sebastián Peláez-Arroyave, Carlos Caicedo-Zamudio, Erick Blanco-Daza, Javier Cuello-López   +7 more
doaj   +1 more source

Molecular heterogeneity and prognostic biomarkers in primary meningeal melanocytic tumors

Brain Pathology, EarlyView.
Integrated molecular profiling reveals biological heterogeneity among primary meningeal melanocytic tumors, identifying intermediate‐grade PMMT subgroups with distinct recurrence risk. Molecular alterations including SF3B1 mutations and chromosome 8q gains support prognostic stratification, while PRKAR1A alterations and chromosome 17/21q losses aid ...
Rosina Paterra, Monica Patanè, Anna Stroppa, Gianluca Marucci, Serena Ammendola, Sofia Asioli, Valeria Barresi   +6 more
wiley   +1 more source

Leptomeninges: Anatomy, Mechanisms of Disease and Neuroimaging

Neurology International
Background: The leptomeninges, comprising the arachnoid and pia mater, serve essential roles in protecting the brain and facilitating cerebrospinal fluid (CSF) circulation. Their significance extends beyond structural support, affecting brain development and function.
Marialuisa Zedde, Rosario Pascarella
openaire   +3 more sources

The HER2 flip-HER2 amplification of tumor cells in the cerebrospinal fluid of breast cancer patients with leptomeningeal disease: implications for treating the LM tumor with anti-HER2 therapy

Frontiers in Oncology
IntroductionCNSide is a platform that detects and characterizes tumor cells in the cerebrospinal fluid (CSF) of patients with leptomeningeal disease (LMD).
Priya U. Kumthekar, Barbara Blouw, Perry Corkos, Seema Nagpal, Arushi Tripathy, David Piccioni, Michael Youssef   +6 more
doaj   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other embryonal tumors

Brain Pathology, EarlyView.
Resource level‐based recommendations on practical diagnostic strategies for medulloblastomas and other CNS embryonal tumors are provided. Abstract WHO CNS5 mandates integrated histo‐molecular classification of medulloblastomas (MBs) and other CNS embryonal tumors. However, advanced molecular diagnostics remain inaccessible in many low‐ and lower‐middle‐
Chitra Sarkar, Maysa Al‐Hussaini, Vani Santosh, Vaishali Suri, Sung‐Hye Park, Yue‐Shan Piao, Tarik Tihan, Ho‐Keung Ng, Michael Buckland, Rakesh Jalali, Yonehiro Kanemura, Pieter Wesseling, Takashi Komori   +12 more
wiley   +1 more source

A Rare Presentation: Leptomeningeal Disease Involving the Left Cerebellar Hemisphere and Lumbosacral Region in Breast Cancer

Leptomeningeal disease (LMD) is a rare condition that occurs in fewer than 5% of breast cancer patients. In certain instances, individuals exhibit symptoms of LMD when initially diagnosed.
Tanzeel, Hamza, Siddiqa, Ayesha, Aziz, Rida, Rida Aziz, Hamza Tanzeel, Shahzadi, Arifa, Arifa Shahzadi, Areeba Aziz, Ayesha Siddiqa, Aziz, Areeba   +9 more
core   +1 more source