Results 121 to 130 of about 5,255,382 (240)

Multicenter Retrospective Study of the Impact of Localized Therapy on Prognosis in Patients With Oligometastatic Solid Tumors

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Background Local therapy has recently been applied to treat oligometastatic cancer across various malignant cancers. However, definitive evidence for local treatment regimens remains lacking. We aimed to evaluate the clinical outcomes of combining local therapy with systemic treatment for patients with oligometastatic solid tumors including ...
Xueman Deng, Duoguang Wu, Luting Ni, Wei Li, Zhijun Liu, Jiewei Liu, Jieqiong Liu   +6 more
wiley   +1 more source

Leptomeningeal carcinomatosis of the spinal cord originating from nasopharyngeal carcinoma

, 2013
We report on a 44-year-old man with nasopharyngeal carcinoma with intracranial extension and leptomeningeal metastases in the spinal cord. Marked resolution of the nasopharyngeal carcinoma and leptomeningeal metastases was achieved by using cisplatin ...
Shum, Tracy C.Y., Ng, W. T.
core   +1 more source

Two Blastic Plasmacytoid Dendritic Cell Neoplasms treated with the CD123‐targeted agent Tagraxofusp presenting divergent outcomes

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Sven C. Engler, Elisabeth M. Walde, Edgar Jost, Amir S. Yazdi, David Kluwig   +4 more
wiley   +1 more source

Angiographic Signatures of Brain Collateralization

International Journal for Numerical Methods in Biomedical Engineering, Volume 42, Issue 11, November 2026.
This article introduces a methodology for quantitatively assessing the degree of collateralization of the brain. The strategy is based on a regional analysis of time‐density curves extracted from dynamic angiographic image sequences. Computational studies were carried out to investigate the dependence of the extracted metrics on the underlying ...
Fernando Mut, Aseem Pradhan, Laurel Marsh, Naoki Kaneko, Juan R. Cebral   +4 more
wiley   +1 more source

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang, Fangjuan Hu, Xiaofeng Wang, Chunhan Tang, Chun Wang, Gefei Jiang, Chungang Zhao, Yin Zhang, Churong Li   +8 more
wiley   +1 more source

Clinicogenomic Features and Outcomes of Adenoid Cystic Carcinoma With Central Nervous System Metastases: A Single‐Institution Cohort Study

Head &Neck, Volume 48, Issue 11, Page 3193-3201, November 2026.
ABSTRACT Background Adenoid cystic carcinoma (ACC) is a rare malignancy with a propensity for perineural invasion and hematogenous spread. Central nervous system (CNS) involvement is uncommon, and detailed clinical and genomic data on this aspect of the disease remain limited.
Omar Elghawy, Jack Stylli, Martin Kurian, Eitan Halper‐Stromberg, Aditi Singh, Christopher D'Avella, Lee Hartner, Roger B. Cohen   +7 more
wiley   +1 more source

Clustering of Cerebral Microbleeds in Cerebral Amyloid Angiopathy: A Flow Territory‐Based Analysis

Journal of Magnetic Resonance Imaging, Volume 64, Issue 5, Page 1241-1249, November 2026.
ABSTRACT Background Cerebral microbleeds (CMBs) are a key imaging marker of cerebral amyloid angiopathy (CAA), but their individual spatial distribution and potential clustering remain poorly understood. Purpose This study assessed whether CMBs exhibit patient‐specific, flow territory‐based clustering in sporadic (sCAA) and Dutch‐type hereditary CAA (D‐
Manon R. Schipper, Reinier G. J. van der Zwet, Jelle J. Goeman, Thijs W. van Harten, Emma A. Koemans, Marieke J. H. Wermer, Marianne A. A. van Walderveen, Matthias J. P. van Osch   +7 more
wiley   +1 more source

Pitfalls in diagnosing and long‐term management of ceroid lipofuscinosis NCL4A in a mixed‐breed dog

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 8‐year‐old, spayed, female, mixed‐breed dog was presented with a 9‐month history of occasionally stumbling on walks, having difficulty navigating stairs and jumping into the car. A prior computed tomography scan of the head revealed mild leptomeningeal enhancement and suggested meningoencephalitis.
Ingeborg Hein, Ines Heinreich, Florian Willmitzer, Marion Mucha   +3 more
wiley   +1 more source

A Diagnostic Quartet in Leptomeningeal Infiltration of the Optic Nerve Sheath

, 1996
A rare case of optic leptomeningeal carcinomatosis secondary to a rectal adenocarcinoma is recorded. The presentation of rectal disease with blindness is unique. A diagnostic quartet of symptoms and signs of leptomeningeal infiltration of the optic nerve
Robert McFadzean, FRCSEd; Donal Brosnahan, FRCSEd; David Doyle, MD; James Going, MRCPath; Donald Hadley, FRCR; William Lee, MD
core  

Diffuse leptomeningeal gliomatosis with oligodendroglioma

, 1999
Leptomeningeal gliomatosis is a primary glioma residing mainly in the leptomeninges. We describe a rare case of diffuse leptomeningeal glioma, occurring in a six year old girl, in which the morphological features of the cellular infiltrates were those of
Poon, Wai Sang, Ng, Ho Keung
core   +1 more source