Results 101 to 110 of about 274,618 (211)

Chiasmatic low-grade glioma presenting with sacral intradural spinal metastasis

, 2000
Leptomeningeal metastasis of low-grade gliomas in children has been documented in several series, both at the time of diagnosis and at relapse. The authors report a unique case of chiasmatic low-grade astrocytoma presenting with signs and symptoms ...
ÖZ, Bülent, AKAR, Ziya Cüneyt, KUDAY, Cengiz, TANRIOVER, Necmettin, KAFADAR, AM, Gazioglu, N, KAFADAR, Ali Metin, ÖZ, B   +7 more
core   +1 more source

Meningeal-tumor interactions define distinct modes of leptomeningeal colonization in Group 3 medulloblastoma

Acta Neuropathologica Communications
Medulloblastoma, the most common malignant brain tumor in children, shows a pronounced tendency to spread to the leptomeninges. Leptomeningeal metastasis accounts for nearly all medulloblastoma-related deaths, yet the cellular and molecular mechanisms ...
Leyre Jimenez Garcia, Lindsay N. Ryan, Amy C. Gross, Annika M. Albrecht, Jefferson H. Walters, Jeffrey R. Leonard, Ryan D. Roberts, James B. Reinecke   +7 more
doaj   +1 more source

Spinal leptomeningeal disease in patients with solid tumors: A single-center study on clinical presentation, diagnosis, treatment, and outcomes

Brain and Spine
Introduction: Despite affecting 5-15% of metastatic cancer patients, leptomeningeal disease (LMD), and spinal LMD (sLMD) in particular, remain largely understudied.
Zoe Shaked, Chiara Eitner, Claudius Jelgersma, Anton Früh, Ran Xu, Helena Radbruch, Jawed Nawabi, Felix Ehret, Güliz Acker, Daniel Zips, Lars Wessels, Ulrich Keilholz, Julia Onken, Martin Misch, Peter Vajkoczy, David Wasilewski   +15 more
doaj   +1 more source

Incidence and Prognostic Factors of Leptomeningeal Metastasis from Non-Small Cell Lung Cancer

, 2012
Objectives: The object of this study is to evaluate the incidence, survival and the prognostic factors in patients with leptomeningeal metastasis from non-small cell lung cancer.
박용구, 장원석, 장진우, 김지희, 김창환   +4 more
core  

A real-world study on clinical features and prognosis of Chinese breast cancer patients with brain metastases

Frontiers in Oncology
BackgroundThis study aimed to analyze the clinical characteristics and prognosis of breast cancer (BC) patients with brain metastases (BM).MethodsWe performed a retrospective analysis of breast cancer patients with brain metastases (BCBM) in a real-world
Hong-dan Chen, Xiao-wen Liao, Xiao-geng Chen, Yu-nan Su, Ding-long Pan, Guo-zhong Chen, Min Wu, Shuang-long Cai   +7 more
doaj   +1 more source

Enhancing meningeal blood vessels masquerading as leptomeningeal spread of tumor in obstructive hydrocephalus

, 1995
MR showed an enhancing mass in the pineal region and hydrocephalus and leptomeningeal enhancement, thought to indicate pinealoblastoma with leptomeningeal spread. During resection there was no evidence of spread, and repeat MR showed no residual tumor or
LeBlang, S D, Falcone, S, Quencer, R M   +2 more
core   +3 more sources

Treatment of Leptomeningeal Disease with Tepotinib in a Patient with Lung Adenocarcinoma Harboring MET Exon 14 Skipping Mutation Presenting with Extensive Metastasis Involving Duodenum

Reports
Background and Clinical Significance: The mesenchymal–epithelial transition (MET) exon 14 skipping mutation (METex14) is a rare genetic alteration occurring in non-small cell lung cancer (NSCLC).
Jacquelyn Shugarts, Aida Amado, Taylor Praska, Monica Camou, Jiaxin Niu   +4 more
doaj   +1 more source

A rare case of leptomeningeal carcinomatosis in a patient with uveal melanoma: case report and review of literature

, 2016
Uveal melanoma is a rare subtype of melanoma, accounting for only 3–5% of all melanoma cases in the USA. Although fewer than 4% of uveal melanoma patients present with metastasis at diagnosis, approximately half will develop metastasis, more than 90% of ...
Harbour, J. William, Linda McIntosh, Forsyth, Peter A, Magliocco, Anthony, Arnold Etame, Evernden, Brittany, Brittany Evernden, Rajappa S. Kenchappa, Keiran S.M. Smalley, Peter A. Forsyth, Sahebjam, Solmaz, Solmaz Sahebjam, Puskas, John, Inna V. Fedorenko, Fedorenko, Inna V, Gisela Caceres, Ryzhova, Elena, McIntosh, Linda, Etame, Arnold, Smalley, Keiran S.M, Elena Ryzhova, John Puskas, Caceres, Gisela, Anthony Magliocco, J. William Harbour, Kenchappa, Rajappa S   +25 more
core   +1 more source

Leptomeningeal metastases in solid tumors [PDF]

, 2014
Background: Leptomeningeal metastases are diagnosed in 1% to 8% of patients with cancer. The most common histology is leukaemia, lymphoma, breast carcinoma, lung carcinoma and melanoma.
Dimitrovska Ivanova, Marija, Karakolevska Ilova, Marija, Simeonovska Joveva, Elena   +2 more
core  

Leptomeningeal metastasis with urological presentation.

Singapore medical journal, 1997
The incidence of clinical leptomeningeal metastases from non-neurologic solid tumour is generally increasing as a result of better survival of systemic cancer with chemotherapy. Their presentation varies according to the neurological involvement. A case of leptomeningeal metastasis from an unknown primary source presenting with urinary incontinence as ...
J J, Chua, P K, Tan, W T, Seow
openaire   +1 more source