Results 81 to 90 of about 22,625 (246)

AAV-mediated netrin-1 overexpression increases peri-infarct blood vessel density and improves motor function recovery after experimental stroke

Neurobiology of Disease, 2011
Apart from its role in axon guidance, netrin-1 is also known to be pro-angiogenic. The aim of this study is to determine whether adeno-associated viral (AAV) mediated overexpression of netrin-1 improves post-stroke neurovascular structure and recovery of
Hui Sun, Thang Le, Tiffany T.J. Chang, Aisha Habib, Steven Wu, Fanxia Shen, William L. Young, Hua Su, Jialing Liu   +8 more
doaj   +1 more source

Efecto de la muerte cerebral en hígados esteatósicos y no esteatósicos sometidos a trasplante

, 2019
[spa] Actualmente, el 80% de los injertos hepático proceden de donantes con muerte cerebral. Sin embargo, la muerte cerebral reduce la tolerancia de los injertos hepáticos a la lesión por isquemia/reperfusión y contrarresta los efectos beneficiosos ...
Negrete Sánchez, Elsa N.
core  

Barcelona 2021 The unique role of Angiogenin in neuroprotection and neurorepair after cerebral ischemia [PDF]

, 2021
L’ictus és una de les principals causes de mort i discapacitat a tot el món amb un gran impacte socioeconòmic i costos sanitaris. Dades recents mostren que hi ha més de 13 milions de nous ictus anualment, una de cada quatre persones majors de 25 anys ...
Lei, Ting
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Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Evaluación del preacondicionamiento isquémico remoto para mejorar la viabilidad de los injertos en trasplante hepático y renal [PDF]

, 2017
Propósito y Método del Estudio: El trasplante renal (TR) como en el trasplante hepático (TH) se han consolidado como el tratamiento de elección para la mayoría de los pacientes con insuficiencia renal crónica terminal y con enfermedades hepáticas ...
Hernández Guedea, Marco Antonio
core  

Biomaterial design strategies for enhancing mitochondrial transplantation therapy

BMEMat, EarlyView.
Biomaterials to facilitate mitochondrial transplantation therapy: biomaterials as barriers to protect mitochondria from pathophysiological microenvironments, like osmotic stress caused by the excessive concentration of calcium ion, reactive oxygen species, and advanced glycation end products; biomaterials integrating with biochemical cues to improve ...
Shaoyang Kang, Yushan Zhang, Hang Li, Sirui Peng, Donghao Lyu, Chunxiao Zhou, Sheng Ding, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Hongjun Wang, Deling Kong, Weiwei Wang   +12 more
wiley   +1 more source

Case Report: Spontaneous recanalization of left anterior descending artery occlusive lesion with OCT-guided drug-coated balloon therapy

Frontiers in Cardiovascular Medicine
In instances where a patient with acute myocardial infarction (AMI) did not undergo immediate reperfusion therapy during the acute phase, there was a risk of the occlusion progressing to chronic and the chances of spontaneous recanalization decreasing ...
Bangguo Yang, Bangguo Yang, Mengqi Yeh, Mengqi Yeh, Jie Bai, Jie Bai   +5 more
doaj   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

Prediction of tissue outcome in acute ischemic stroke based on single-phase CT angiography at admission

Frontiers in Neurology
IntroductionIn acute ischemic stroke, prediction of the tissue outcome after reperfusion can be used to identify patients that might benefit from mechanical thrombectomy (MT). The aim of this work was to develop a deep learning model that can predict the
Frosti Palsson, Frosti Palsson, Nils D. Forkert, Nils D. Forkert, Nils D. Forkert, Nils D. Forkert, Lukas Meyer, Gabriel Broocks, Fabian Flottmann, Máté E. Maros, Matthias Bechstein, Laurens Winkelmeier, Eckhard Schlemm, Jens Fiehler, Susanne Gellißen, Helge C. Kniep   +15 more
doaj   +1 more source

Activation of autophagy in a rat model of retinal ischemia following high intraocular pressure.

PLoS ONE, 2011
Acute primary open angle glaucoma is an optic neuropathy characterized by the elevation of intraocular pressure, which causes retinal ischemia and neuronal death.
Antonio Piras, Daniele Gianetto, Daniele Conte, Alex Bosone, Alessandro Vercelli   +4 more
doaj   +1 more source