Results 91 to 100 of about 3,826,952 (368)
Accurate Segmentation and Registration of Skin Lesion Images to Evaluate Lesion Change
IEEE journal of biomedical and health informatics, 2019 Skin cancer is a major health problem. There are several techniques to help diagnose skin lesions from a captured image. Computer-aided diagnosis (CAD) systems operate on single images of skin lesions, extracting lesion features to further classify them ...
F. Navarro +2 more
semanticscholar +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Revista Brasileira de Parasitologia Veterinária, 2017 The aim of the present study was to investigate the occurrence of N. caninum associated with abortions of dairy cattle from Santa Catarina state, southern Brazil by using enzyme-linked immunosorbent assay (ELISA), immunohistochemistry (IHC), and ...
Cesar Augusto Barbosa de Macedo +10 more
doaj +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Detecting Lesion Bounding Ellipses With Gaussian Proposal Networks
, 2019 Lesions characterized by computed tomography (CT) scans, are arguably often elliptical objects. However, current lesion detection systems are predominantly adopted from the popular Region Proposal Networks (RPNs) that only propose bounding boxes without ...
K Yan, K Yan
core +1 more source
HeliyonBackground and aim: Cystic dilatation of the gastric glands within the mucosal layer is the hallmark of the rare condition known as gastritis cystica profunda (GCP).
Wei Jiang +3 more
doaj +1 more source
Functional MRI preprocessing in lesioned brains: manual versus automated region of interest analysis
Frontiers in Neurology, 2015 Functional magnetic resonance imaging has significant potential in the study and treatment of neurological disorders and stroke. Region of interest (ROI) analysis in such studies allows for testing of strong a priori clinical hypotheses with improved ...
Kathleen A Garrison +11 more
doaj +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Lesion network localization of free will
Proceedings of the National Academy of Sciences of the United States of America, 2018 Significance Free will consists of a desire to act (volition) and a sense of responsibility for that action (agency), but the brain regions responsible for these processes remain unknown.
R. Darby +4 more
semanticscholar +1 more source