Results 31 to 40 of about 1,603,635 (269)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Triglyceride–glucose index in the associations between chronic low-grade inflammation and carotid intima-media thickness: mediation and effect-modification across triglyceride–glucose strata

BMC Cardiovascular Disorders
Aims Atherosclerosis is established as a chronic inflammatory disease, yet the potential mediating role of glucose and lipid metabolism in inflammation-driven atherogenesis has not been fully elucidated.
Xueguang Lin, Shishuai Xie, Bingbing Pu, Zheyu Wang, Hui Zhang, Yunxia Li, Jingdong Tang, Bo Yu, Shuai Jiang   +8 more
doaj   +1 more source

Pathogenicity of Salmonella enterica subspecies enterica serovar Enteritidis phage type 1 in one-day-old specific pathogen free chicks

Open Veterinary Journal, 2022
Background and Aim: The studies about Salmonella infection in the newly hatched chicks were not extensive. The objective of this study was to determine pathogenicity of Salmonella enterica subspecies enterica serovar Enteritidis (SE) phage type (PT) 1 in
S. Ahmad, M. Hair-Bejo, Elawad A. Hussein, E. A Awad, Mohamed Ibrahim Saeed, Liew Pit Sze, Zunita Zakaria   +6 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source

ACSL1 Aggravates Thromboinflammation by LPC/LPA Metabolic Axis in Hyperlipidemia Associated Myocardial Ischemia‐Reperfusion Injury

Advanced Science
Acute myocardial infarction (AMI) is associated with well‐established metabolic risk factors, especially hyperlipidemia and obesity. Myocardial ischemia‐reperfusion injury (mIRI) significantly offsets the therapeutic efficacy of revascularization ...
Shuai Jiang, Xueguang Lin, Bo Chen, Gang Chen, Kristine J.S. Kwan, Jing Liu, Qi Sun, Jie Wang, Yijie Lu, Jindong Tong, Ying Deng, Bo Yu, Jingdong Tang   +12 more
doaj   +1 more source

Brain architecture-based vulnerability to traumatic injury

Frontiers in Bioengineering and Biotechnology, 2022
The white matter tracts forming the intricate wiring of the brain are subject-specific; this heterogeneity can complicate studies of brain function and disease.
Jared A. Rifkin, Jared A. Rifkin, Taotao Wu, Adam C. Rayfield, Erin D. Anderson, Matthew B. Panzer, Matthew B. Panzer, David F. Meaney, David F. Meaney   +8 more
doaj   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source

Pathological Findings in Cattle Slaughtered in Northeastern Algeria and Associated Risk Factors

Veterinary Sciences, 2022
Meat is a food of animal origin, which can be contaminated by infectious, parasitic and other non-infectious agents responsible for diseases, which threaten the health of consumers.
Nora Mimoune, Mourad Hamiroune, Said Boukhechem, Choayb Mecherouk, Khaled Harhoura, Djamel Khelef, Rachid Kaidi   +6 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

Sensory-to-motor integration during auditory repetition: A combined fMRI and lesion study

Frontiers in Human Neuroscience, 2014
The aim of this paper was to investigate the neurological underpinnings of auditory-to-motor translation during auditory repetition of unfamiliar pseudowords. We tested two different hypotheses.
‘Ōiwi eParker Jones, ‘Ōiwi eParker Jones, Susan ePrejawa, Tom eHope, Marion eOberhuber, Mohamed L Seghier, Alex P Leff, David W Green, Cathy J Price   +8 more
doaj   +1 more source