Results 91 to 100 of about 2,984 (199)

Letermovir for the prevention of cytomegalovirus infection and disease in transplant recipients: an evidence-based review

Infection and Drug Resistance, 2019
Guy El Helou,1,2 Raymund R Razonable1,21Division of Infectious Diseases, Department of Medicine, Mayo Clinic, Rochester, MN, USA; 2William J von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN, USAAbstract ...
El Helou G, Razonable RR
doaj  

Risk factors for hemorrhagic cystitis after allogeneic hematopoietic stem cell transplantation in a letermovir-exposed CMV-free population receiving PTCy [PDF]

Hemorrhagic cystitis (HC) is a highly impacting complication in allogeneic hematopoietic stem cell transplantation (HSCT), occurring in 12%–37% of patients. The impact of transplant- and patient-specific variables has been described, with a possible role
Bacigalupo, A., Chiusolo, P., Galli, E., Gandi, C., Mattozzi, A., Metafuni, E., Santangelo, R., Sica, S., Sora', F.   +8 more
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ID222 Análise de custo-efetividade e impacto orçamentário do letermovir como profilaxia da infecção e doença por citomegalovírus em pacientes adultos soropositivos (CMV R+) receptores de transplante de células-tronco hematopoiéticas alogênico, na perspectiva do Sistema Único de Saúde

Jornal de Assistência Farmacêutica e Farmacoeconomia
Introdução A população de pacientes submetidos ao transplante de células tronco hematopoiéticas (TCTH) é mais suscetível a infecções, devido ao estado imunocomprometido.
Álex Brunno do Nascimento Martins, Bárbara Rodrigues Alvernaz dos Santos, Eduardo Henrique Ferreira Bambirra, Francisco de Assis Acurcio, Luana Oliveira Prata, Juliana Alvares-Teodoro, Maiara Silva Araújo, Roberto Lúcio Muniz Júnior, Wallace Breno Barbosa, Augusto Afonso Guerra Júnior   +9 more
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Letermovir Prophylaxis for Cytomegalovirus Infection in Allogeneic Stem Cell Transplantation: A Real-World Experience [PDF]

, 2021
Attolico, I., Bruno, B., Busca, A., Canale, F. A., Carella, A. M., Carluccio, P., Cerchione, C., Cimminiello, M., Colasante, F., Crescimanno, A., Di Renzo, N., Federico, V., Ferreri, A., Giaccone, L., Gori, M., Ingrosso, C., Leotta, S., Loteta, B., Marotta, S., Martinelli, G., Martino, M., Mazza, P., Merla, E., Mordini, N., Musso, M., Musto, P., Musuraca, G., Pastore, D., Paviglianiti, A., Picardi, A., Pitino, A., Porto, G., Prezioso, L., Pugliese, M., Scalone, R., Selleri, C., Serio, B., Storti, G., Tringali, S., Tripepi, G., Vacca, A.   +40 more
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Antiviral resistance and persistent replication of cytomegalovirus and SARS-CoV-2 in immunocompromised patients [PDF]

, 2022
[eng] The main objectives of this thesis are to study the opportunistic infection caused by human cytomegalovirus and SARS-CoV-2 inquiring persistent infection and antiviral resistance.
Santos Bravo, Marta
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Efficacy and safety of letermovir prophylaxis for cytomegalovirus infection after hematopoietic stem cell transplantation

Blood Science
Letermovir is a specific inhibitor of cytomegalovirus (CMV) terminase complex. Several studies have reported that letermovir can effectively prevent CMV activation after allogeneic hematopoietic stem cell transplantation (allo-HSCT). We aimed to identify
Wen-Wen Li, Yong-Mei Zhang, Meng-Zhu Shen, Xiao-Dong Mo   +3 more
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Cellular Therapeutic Approaches to Cytomegalovirus Infection Following Allogeneic Stem Cell Transplantation [PDF]

, 2020
INTRODUCTION Cytomegalovirus (CMV) infection following allogeneic hematopoietic stem cell transplantation (HSCT) is a major cause of morbidity and mortality.
Mehra, V, Peggs, KS, Roddie, C, Shafat, MS   +3 more
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Letermovir Analytical Methods Development and Validation: In-Silico Insights and Characterization [PDF]

Combining computational and experimental methods is necessary due to the increasing complexity of antiviral drug discovery and the requirement for robust analytical quality control.
Ritika Pal, Vaishali, Sudhansu Ranjan Swain
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A fifty-year odyssey: prospects for a cytomegalovirus vaccine in transplant and congenital infection

Expert Review of Vaccines, 2018
Introduction: It has been almost fifty years since the Towne strain was used by Plotkin and collaborators as the first vaccine candidate for cytomegalovirus (CMV).
Don Jeffrey Diamond, Corinna La Rosa, Flavia Chiuppesi, Heidi Contreras, Sanjeet Dadwal, Felix Wussow, Supriya Bautista, Ryotaro Nakamura, John A. Zaia   +8 more
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Coadministration of isavuconazole and sirolimus in allogeneic hematopoietic stem cell transplant recipients [PDF]

Background: Invasive fungal infections (IFIs) represent a major cause of morbidity among allogeneic hematopoietic stem cell transplantation (allo-HSCT). Isavuconazole (ISA) is a broad-spectrum triazole with favorable safety profile. Objectives and design:
Acerbis A., Bruno A., Campodonico E., Castagna A., Chiurlo M., Ciceri F., Clerici D., Corti C., Dell'Acqua R., Diral E., Farina F., Greco R., Marktel S., Mastaglio S., Oltolini C., Orofino G., Peccatori I., Piemontese S., Scarpellini P., Teresa Lupo Stanghellini M., Xue E.   +20 more
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