Results 81 to 90 of about 2,984 (199)

Usage of Antivirals and the Occurrence of Antiviral Resistance in Norway 2019. RAVN [PDF]

open access: yes, 2020
The usage of antivirals According to The Norwegian Drug Wholesales statistics database, the sales of antiviral drugs measured in defined daily doses (DDDs) continued to increase in 2018.
Bragstad, Karoline   +5 more
core  

Stewardship of Molecular Diagnostics in Transplant Viral Infections

open access: yesTransplant Infectious Disease, Volume 28, Issue 1, January/February 2026.
ABSTRACT The transplant environment requires special considerations when testing for viral infections as immunosuppression results in atypical infection profiles. Microbes otherwise considered commensals or causing mild disease can lead to severe infections in transplant environments. Therefore, guidelines tend to recommend broader microbial testing in
Scott Sugden   +3 more
wiley   +1 more source

Current and Emerging Antiviral Agents in the Prevention and Treatment of Cytomegalovirus in Pediatric Transplant Recipients [PDF]

open access: yes
Despite current prophylaxis regimens, cytomegalovirus (CMV) is common in hematopoietic cell transplantation (HCT) and solid organ transplantation (SOT) and remains a significant cause of morbidity and mortality.
Danziger-Isakov, Lara A   +2 more
core   +2 more sources

Baseline Cytomegalovirus Immunoglobulin G Levels Predict Reactivation in Patients With Multiple Myeloma Receiving Elranatamab

open access: yeseJHaem, Volume 6, Issue 6, December 2025.
ABSTRACT Background The cumulative incidence and risk of cytomegalovirus (CMV) reactivation in patients with relapsed/refractory multiple myeloma (RRMM) receiving elranatamab remain unclear. Methods We retrospectively analyzed RRMM patients treated with elranatamab to assess cumulative incidence and risk factors for CMV reactivation.
Ukyo Kondo   +13 more
wiley   +1 more source

Discovery and Characterization of Cytomegalovirus Inhibitors using Reporter-based Antiviral Assays [PDF]

open access: yes, 2017
DISCOVERY AND CHARACTERIZATION OF CYTOMEGALOVIRUS INHIBITORS USING REPORTER-BASED ANTIVIRAL ASSAYS By Amine Ourahmane, MS A thesis submitted in partial fulfillment of the requirements for the degree of Master of Science at Virginia Commonwealth ...
ourahmane, amine
core   +1 more source

Utility of Serial Microbial Cell-free DNA Sequencing for Inpatient and Outpatient Pathogen Surveillance Among Allogeneic Hematopoietic Stem Cell Transplant Recipients. [PDF]

open access: yes
BACKGROUND: This study characterizes the clinical utility and validity of the Karius test (KT), a plasma microbial cell-free DNA sequencing platform, as an infection surveillance tool among hematopoietic stem cell transplant (HCT) recipients, including ...
Chin-Hong, Peter   +11 more
core   +1 more source

Clinical and Economic Burden of Cytomegalovirus (CMV) Infection/Disease Among Hospitalized Adult Allogeneic Hematopoietic Stem Cell Transplant (Allo‐HSCT) Recipients in China

open access: yesJournal of Medical Virology, Volume 97, Issue 12, December 2025.
ABSTRACT Cytomegalovirus (CMV) infection is a prevalent complication among allogeneic hematopoietic stem cell transplant (allo‐HSCT) recipients, posing significantly impact on clinical outcomes and healthcare costs. This study aims to assess the clinical and economic burden of CMV infection in hospitalized adult allo‐HSCT recipients in China.
Chenhua Yan   +10 more
wiley   +1 more source

Management of Cytomegalovirus Infections in the Era of the Novel Antiviral Players, Letermovir and Maribavir

open access: yesInfectious Disease Reports
Cytomegalovirus (CMV) infections may increase morbidity and mortality in immunocompromised patients. Until recently, standard antiviral drugs against CMV were limited to viral DNA polymerase inhibitors (val)ganciclovir, foscarnet and cidofovir with a ...
Jocelyne Piret, Guy Boivin
doaj   +1 more source

Post‐Transplant Cyclophosphamide for Graft‐Versus‐Host Disease Prophylaxis in Pediatric Stem Cell Transplantation

open access: yesPediatric Blood &Cancer, Volume 72, Issue 12, December 2025.
ABSTRACT Graft‐Versus‐Host disease (GVHD) is a leading contributor to morbidity and mortality following stem cell transplantation (SCT). Current GVHD prevention methods utilize a combination of immunosuppressive drugs to prevent injury to host tissues.
Aaron E. Fan   +6 more
wiley   +1 more source

DNA Encapsidation and Capsid Assembly Are Underexploited Antiviral Targets for the Treatment of Herpesviruses

open access: yesFrontiers in Microbiology, 2020
Although there are effective nucleoside analogs to treat HSV, VZV, and HCMV disease, herpesvirus infections continue to contribute to significant morbidity and mortality. Acyclovir is the drug of choice for HSV encephalopathy, yet there is an estimated 6–
Tara Keil   +5 more
doaj   +1 more source

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