Results 161 to 170 of about 345,070 (206)
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The lethal heat dose for 50% primary human fibroblast cell death is 48 °C
Archives of Dermatological Research, 2021Understanding the effect of heat on skin cells is important for the prevention of burn injury. Knowledge of the heat dose required to kill cells can be used to study the cellular mechanisms involved in thermal injury cell death, to assist with the development of novel burn treatments. In this study, primary human skin dermal fibroblasts were exposed to
Elissa Henderson +8 more
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Determination of acute lethal dose 50 (LD50) of uranyl nitrate in male swiss albino mice
Research Journal of Pharmacy and Technology, 2018Evaluation of LD50 is the foremost step in the assessment of toxicity of a substance. The present study was designed to determine the acute LD50 of uranyl nitrate via intraperitoneal route in male swiss albino mice. The selected single doses of uranyl nitrate from the pilot study conducted were 64, 32, 16, 8, 4mg/kg bdwt.
Sangeetha P. Vijayan +3 more
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Endocrinology, 1978
Effects of intraventricular injection of sheep anti-somatostatin gamma-globulin (anti-SSG) on strychnine-induced seizures, strychnine LD50, and pentobarbital LD50 were examined in male rats under light ether anesthesia. Ten microliters of anti-SSG given 2 h earlier significantly decreased the duration of strychnine-induced seizures as compared with ...
K, Chihara +3 more
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Effects of intraventricular injection of sheep anti-somatostatin gamma-globulin (anti-SSG) on strychnine-induced seizures, strychnine LD50, and pentobarbital LD50 were examined in male rats under light ether anesthesia. Ten microliters of anti-SSG given 2 h earlier significantly decreased the duration of strychnine-induced seizures as compared with ...
K, Chihara +3 more
openaire +2 more sources
Toxicon, 2020
Palytoxin is an emergent toxin in Europe and one of the most toxic substances know to date. The toxin disrupts the physiological functioning of the Na+/K+-ATPase converting the enzyme in a permeant cation channel. Human intoxications by PLTX after consumption of contaminated fishery products are a serious health issue and can be fatal.
Andrea Boente-Juncal +5 more
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Palytoxin is an emergent toxin in Europe and one of the most toxic substances know to date. The toxin disrupts the physiological functioning of the Na+/K+-ATPase converting the enzyme in a permeant cation channel. Human intoxications by PLTX after consumption of contaminated fishery products are a serious health issue and can be fatal.
Andrea Boente-Juncal +5 more
openaire +2 more sources
[Ciradian variation in the lethal dose 50 of mercuric chloride in mice].
Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie, 1982If circadian variations in tolerance to drugs have been often demonstrated, such observations about heavy metals are still very scarce. The present study proposes to determine if circadian variations occur in the tolerance of Mice to single lethal dose of mercuric chloride. 360 female Mice, kept in cages on a 8.00 - 20.00 L/D cycle, receive I.P.
J, Cambar, J C, Cal
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The Journal of Immunology, 1954
Summary Counting of elementary bodies of meningo-pneumonitis virus in dialysed allantoic fluid by electron microscopy is described. Dialysis against distilled water for 18 to 24 hours at 5°C did not alter the lethal potency of the fluid for chick embryos inoculated via the yolk sac.
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Summary Counting of elementary bodies of meningo-pneumonitis virus in dialysed allantoic fluid by electron microscopy is described. Dialysis against distilled water for 18 to 24 hours at 5°C did not alter the lethal potency of the fluid for chick embryos inoculated via the yolk sac.
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Veterinary Parasitology, 1998
The relationship between resistance detected in the faecal egg count reduction test (FECRT) and the lethal dose 50% (LD50) in the egg hatch assay (EHA) for benzimidazoles (BZs) and a larval development assay (LDA) for BZs, levamisole (LEV) and ivermectin (IVM) was examined on 13 sheep farms and 12 goat farms in Denmark. Out of 10 farms where resistance
Dangolla, A, Bjørn, H, Maingi, N
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The relationship between resistance detected in the faecal egg count reduction test (FECRT) and the lethal dose 50% (LD50) in the egg hatch assay (EHA) for benzimidazoles (BZs) and a larval development assay (LDA) for BZs, levamisole (LEV) and ivermectin (IVM) was examined on 13 sheep farms and 12 goat farms in Denmark. Out of 10 farms where resistance
Dangolla, A, Bjørn, H, Maingi, N
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Journal of Toxicology and Environmental Health, 1977
A program for a small digital computer was developed to calculate the median lethal dose (LD50) and its errors. The algorithm employed in the program was based on a method described by Bliss. Modifications introduced by Finney are also discussed. The results indicate a high degree of accuracy compared with calculations performed by Bliss.
A P, Rosiello +2 more
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A program for a small digital computer was developed to calculate the median lethal dose (LD50) and its errors. The algorithm employed in the program was based on a method described by Bliss. Modifications introduced by Finney are also discussed. The results indicate a high degree of accuracy compared with calculations performed by Bliss.
A P, Rosiello +2 more
openaire +2 more sources