Results 31 to 40 of about 4,473,042 (255)

MHC Class II and Non-MHC Class II Genes Differentially Influence Humoral Immunity to Bacillus anthracis Lethal Factor and Protective Antigen

open access: yesToxins, 2012
Anthrax Lethal Toxin consists of Protective Antigen (PA) and Lethal Factor (LF), and current vaccination strategies focus on eliciting antibodies to PA. In human vaccination, the response to PA can vary greatly, and the response is often directed toward ...
Judith A. James   +8 more
doaj   +1 more source

The Relationship Between a Person's Criminal History, Immediate Situational Factors, and Lethal Versus Non-Lethal Events [PDF]

open access: yes, 2015
When investigating serious violence, studies tend to look primarily at offenders and their background. This study investigates the influence of offenders' and victims' criminal history and immediate situational factors on the likelihood that violent ...
Nieuwbeerta, P.   +10 more
core   +1 more source

Anthrax Lethal Toxin and the Induction of CD4 T Cell Immunity

open access: yesToxins, 2012
Bacillus anthracis secretes exotoxins which act through several mechanisms including those that can subvert adaptive immunity with respect both to antigen presenting cell and T cell function.
Daniel M. Altmann   +2 more
doaj   +1 more source

Lethality by pneumonia and factors associated to death

open access: yesJornal de Pediatria (Versão em Português), 2014
To describe the case-fatality rate (CFR) and risk factors of death in children with community-acquired acute pneumonia (CAP) in a pediatric university hospital.A longitudinal study was developed with prospective data collected from 1996 to 2011. Patients aged 1 month to 12 years were included in the study.
Ferreira, Sidnei   +4 more
openaire   +7 more sources

Antibodies against Anthrax: Mechanisms of Action and Clinical Applications

open access: yesToxins, 2011
B. anthracis is a bioweapon of primary importance and its pathogenicity depends on its lethal and edema toxins, which belong to the A-B model of bacterial toxins, and on its capsule.
Thibaut Pelat   +2 more
doaj   +1 more source

Occurrence of lethal bleeding in factor VIII deficient mice.

open access: yes, 2016
Occurrence of lethal bleeding in factor VIII deficient mice.
Molly J. Pollpeter (2657014)   +1 more
core   +1 more source

Toxin and lethal factor domains found in N11P.

open access: yes, 2015
Toxin and lethal factor domains found in N11P.
Susan Weininger (694460)   +1 more
core   +1 more source

A Lyophilizable Nanoparticle Vaccine Specific for a Novel Linear Neutralizing Epitope in the α2-α3 Helices of Domain 3 of Lethal Factor from Bacillus anthracis

open access: yesToxins
Anthrax remains a serious bioterrorism threat for which new and thermostable vaccines are needed. We previously demonstrated that immunization of rabbits with multiple-antigenic-peptide (MAP) vaccines elicit antibody (Ab) against the loop-neutralizing ...
Jon Oscherwitz   +5 more
doaj   +1 more source

Asp 187 and Phe 190 residues in lethal factor are required for the expression of anthrax lethal toxin activity

open access: yes, 2002
Anthrax toxin consists of three proteins, protective antigen, lethal factor, and edema factor. Protective antigen translocates lethal factor and edema factor to the cytosol of mammalian cells.
Bhatnagar, Rakesh   +3 more
core   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

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