Results 1 to 10 of about 4,688 (70)

Antigenic identity of immunodominant proteins of Bacillus anthracis genovariants

Журнал микробиологии, эпидемиологии и иммунобиологии, 2023
Introduction. The main biological raw materials for the production of immunobiological preparations for identification of Bacillus anthracis are its specific antigens, the protective antigen and the EA1 protein. Purpose.
Margarita P. Izhberdeeva, Anastasiya A. Sautkina, Irina A. Barkova, Dmitry V. Viktorov   +3 more
doaj   +1 more source

Binding Sites of Anti-Lcr V Monoclonal Antibodies Are More Critical than the Avidities and Affinities for Passive Protection against Yersinia pestis Infection in a Bubonic Plague Model

Antibodies, 2020
Plague is a zoonotic disease that is caused by Yersinia pestis. Monoclonal antibodies (mAbs) that bind to the V-antigen, a virulence factor that is produced by Y. pestis, can passively protect mice from plague. An analysis of protective mAbs that bind to
Kei Amemiya, Jennifer L. Dankmeyer, Sarah L. Keasey, Sylvia R. Trevino, Michael M. Wormald, Stephanie A. Halasohoris, Wilson J. Ribot, David P. Fetterer, Christopher K. Cote, Patricia L. Worsham, Jeffrey J. Adamovicz, Robert G. Ulrich   +11 more
doaj   +1 more source

Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications

Microorganisms, 2020
Anthrax toxins are produced by Bacillus anthracis throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient.
Jean-Nicolas Tournier, Clémence Rougeaux   +1 more
doaj   +1 more source

A Quantum Vaccinomics Approach for the Design and Production of MSP4 Chimeric Antigen for the Control of Anaplasma phagocytophilum Infections

Vaccines, 2022
Anaplasma phagocytophilum Major surface protein 4 (MSP4) plays a role during infection and multiplication in host neutrophils and tick vector cells. Recently, vaccination trials with the A.
José de la Fuente, Alberto Moraga-Fernández, Pilar Alberdi, Sandra Díaz-Sánchez, Olga García-Álvarez, Rubén Fernández-Melgar, Marinela Contreras   +6 more
doaj   +1 more source

Genetic Construction of Bacillus subtilis Recombinant Strain, Producing Protective Antigen of Anthrax Microbe

Вестник войск РХБ защиты, 2023
Anthrax is a serious infectious disease with high mortality. The epidemiological security depends on the vaccination of susceptible animals and population at risk.
N. V. Onuchina, A. V. Kuznetsovsky, A. A. Vorobyov, A. V. Filippov   +3 more
doaj   +1 more source

Vaccinal Preventon of Anthrax in the Russian Federation and Its Immediate Prospects

Вестник войск РХБ защиты, 2023
The purpose of the work is to show the possibilities of vaccine prophylaxis of anthrax in the Russian Federation and its immediate prospects. The article is dedicated to the vaccine preparations, available in Russia and abroad in the arsenal of medical ...
A. N. Shevtsov, O. V. Korotyshev, S. A. Permyakov, I. P. Pogorelsky   +3 more
doaj   +1 more source

Development of a New Cell-Based AP-1 Gene Reporter Potency Assay for Anti-Anthrax Toxin Therapeutics

Toxins, 2023
Anthrax toxin is a critical virulence factor of Bacillus anthracis. The toxin comprises protective antigen (PA) and two enzymatic moieties, edema factor (EF) and lethal factor (LF), forming bipartite lethal toxin (LT) and edema toxin (ET).
Weiming Ouyang, Tao Xie, Hui Fang, David M. Frucht   +3 more
doaj   +1 more source

Current understanding of Bacillus anthracis toxin molecules organization and approaches for blocking their cytotoxic action

Инфекция и иммунитет, 2020
Here, we review the data on mechanisms inhibiting cytotoxic effect of anthrax toxin on the immune system cells. Various disease forms, immunopathogenesis and contemporary methods for anthrax treatment are discussed.
V. V. Firstova, I. G. Shemyakin, I. A. Dyatlov   +2 more
doaj   +1 more source

Retrospective Screening of Anthrax-like Disease Induced by Bacillus tropicus str. JMT from Chinese Soft-Shell Turtles in Taiwan

Pathogens, 2023
Bacillus cereus is ubiquitous in the environment and a well-known causative agent of foodborne disease. Surprisingly, more and more emerging strains of atypical B.
Jia-Ming Tsai, Hsin-Wei Kuo, Winton Cheng   +2 more
doaj   +1 more source

Trimethyl Chitosan Nanoparticles Encapsulated Protective Antigen Protects the Mice Against Anthrax

Frontiers in Immunology, 2018
Anthrax is an era old deadly disease against which there are only two currently available licensed vaccines named anthrax vaccine adsorbed and precipitated (AVP).
Anshu Malik, Manish Gupta, Rajesh Mani, Himanshu Gogoi, Rakesh Bhatnagar   +4 more
doaj   +1 more source