Results 11 to 20 of about 531,678 (162)
Вестник войск РХБ защиты, 2023 Anthrax is a serious infectious disease with high mortality. The epidemiological security depends on the vaccination of susceptible animals and population at risk.
N. V. Onuchina +3 more
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Immunotropic and Immunogenic Properties of Nonspecific Yersinia Porins
Вестник войск РХБ защиты, 2023 The purpose of the study is to summarize our own data and literature data on the significance of poreforming proteins of the outer membrane of Yersinia as factors of their pathogenicity and as diagnostic and protective antigens, and their role in ...
O. D. Novikova +3 more
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Инфекция и иммунитет, 2020 Here, we review the data on mechanisms inhibiting cytotoxic effect of anthrax toxin on the immune system cells. Various disease forms, immunopathogenesis and contemporary methods for anthrax treatment are discussed.
V. V. Firstova +2 more
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Antigens of Bordetella pertussis.III. The Protective Antigen
Experimental Biology and Medicine, 1963 SummaryA method of preparing extracts from Bordetella pertussis with high protective and histamine sensitizing activity is described. From these extracts, starch block electrophoresis yielded active purified fractions which not only protected mice against intracerebral challenge with living B. pertussis cells but also sensitized mice to histamine. From
J, MUNOZ, B M, HESTEKIN
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Recombinant HSA-CMG2 Is a Promising Anthrax Toxin Inhibitor
Toxins, 2016 Anthrax toxin is the major virulence factor produced by Bacillus anthracis. Protective antigen (PA) is the key component of the toxin and has been confirmed as the main target for the development of toxin inhibitors.
Liangliang Li +8 more
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Evaluation of Crude Anthrax Protective Antigen as an Adjutant For Brucella Abortus Vaccine In Mice [PDF]
Engineering and Technology Journal, 2012 Anthrax crude protective antigen (PA) was used in this study as an adjutant with Brucella abortus S19 strain vaccine in a ratio of 1:1 to immunize mice in dose of 0.1 ml s/c in order to decrease side effects of S19 vaccine and also to enhance its ...
Inam Jasim Lafta
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Why is a protective antigen protective?
Human Vaccines, 2009 One of the major challenges in vaccine development is the identification of microbial components that give rise to a protective immune response. Over the last decade, genome and proteome-based methods have proven successful in discovering new vaccine candidates for many pathogens through the selection of secreted or surface-exposed protein antigens and
L.J. Gourlay +5 more
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Toxins, 2016 Nearly all the cationic molecules tested so far have been shown to reversibly block K+ current through the cation-selective PA63 channels of anthrax toxin in a wide nM–mM range of effective concentrations.
Goli Yamini +2 more
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New protective antigen of group A streptococci [PDF]
Journal of Clinical Investigation, 1999 It is widely believed that the surface M protein of group A streptococci is the predominant surface protein of these organisms containing opsonic epitopes. In the present study, we identified a new surface protein, distinct from M protein, that evokes protective antibodies.
J B, Dale +4 more
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Toxins, 2014 Anthrax Vaccine Adsorbed (AVA) generates short-lived protective antigen (PA) specific IgG that correlates with in vitro toxin neutralization and protection from Bacillus anthracis challenge.
Lori Garman +5 more
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