Results 31 to 40 of about 1,531,051 (248)

Vaccines against toxoplasma gondii : challenges and opportunities [PDF]

open access: yes, 2009
Development of vaccines against Toxoplasma gondii infection in humans is of high priority, given the high burden of disease in some areas of the world like South America, and the lack of effective drugs with few adverse effects.
Jongert, Erik   +4 more
core   +4 more sources

Influence of the Protective Antigen, Produced by Bacillus anthracis Asporogenic Recombinant Strain, on the Immune System of Laboratory Animals

open access: yesПроблемы особо опасных инфекций, 2012
Assessment of immunogenicity and biological safety of protective antigen preparation obtained from asporogenic recombinant producer, B. anthracis 55ΔTPA-1(Spo-), is made on the mice (BALB/c species) and Guiney pigs models.
P. Yu. Popova   +9 more
doaj   +1 more source

IL-4 receptor expression on CD8+ T cells is required for the development of protective memory responses against liver stages of malaria parasites. [PDF]

open access: yes, 2005
IL-4 receptor (IL-4R)-deficient CD8+ T cells specific for the circumsporozoite protein of Plasmodium yoelii develop a severely impaired memory response after priming with parasites.
Morrot, Alexandre   +9 more
core   +1 more source

Bacillus anthracis Protective Antigen Kinetics in Inhalation Spore-Challenged Untreated or Levofloxacin/ Raxibacumab-Treated New Zealand White Rabbits

open access: yesToxins, 2013
Inhaled Bacillus anthracis spores germinate and the subsequent vegetative growth results in bacteremia and toxin production. Anthrax toxin is tripartite: the lethal factor and edema factor are enzymatic moieties, while the protective antigen (PA) binds ...
Cecil Chen   +6 more
doaj   +1 more source

Rapid and Sensitive Multiplex Assay for the Detection of B. anthracis Spores from Environmental Samples

open access: yesPathogens, 2020
: Prompt and accurate detection of Bacillus anthracis spores is crucial in the event of intentional spore dissemination in order to reduce the number of expected casualties.
Efi Makdasi   +5 more
doaj   +1 more source

Immunotropic and Immunogenic Properties of Nonspecific Yersinia Porins

open access: yesВестник войск РХБ защиты, 2023
The purpose of the study is to summarize our own data and literature data on the significance of poreforming proteins of the outer membrane of Yersinia as factors of their pathogenicity and as diagnostic and protective antigens, and their role in ...
O. D. Novikova   +3 more
doaj   +1 more source

Microsomal membranes from antigen presenting cells present antigenic peptides to T cells: a novel approach in vaccine development. [PDF]

open access: yes, 2010
PhDThe study of the immune system has provided insight in the mechanism of protection induced by vaccination; primarily that most clinically protective vaccines are potent in generating neutralizing antibody responses.
Sofra, Vasiliki
core   +4 more sources

Cloning, expression and sequence analysis of Al gene in Aeromonas hydrophila strains TPS-30 and BSK-10

open access: yes浙江大学学报. 农业与生命科学版, 2010
Adhesin is an important pathogenic factor of Aeromonas hydrophila which can cause disease in most fish in the area of Jiangsu and Zhejiang. The strains of TPS-30 and BSK-10 were assigned to serogroup O:9 and O:97 respectively, and the genes of the major ...
PAN Xiao-yi   +4 more
doaj   +1 more source

Mixed allele malaria vaccines: Host protection and within-host selection [PDF]

open access: yes, 2008
Malaria parasites are frequently polymorphic at the antigenic tat-gets of many candidate vaccines, presumably as a consequence of selection pressure from protective immune responses.
Anders, Robin F.   +5 more
core   +1 more source

Immunization with Individual Proteins of the Lrp/AsnC Family Induces Protection Against Brucella melitensis 16M Challenges in Mice

open access: yesFrontiers in Microbiology, 2015
Brucellosis is one of the most common zoonoses worldwide. Subunit vaccines are promising for the prevention of human brucellosis. In our previous protective antigen screening studies, we identified a new protective antigen, BMEI0357, which belongs to the
Xinhui eWang   +17 more
doaj   +1 more source

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