Results 11 to 20 of about 326,608 (291)

Family Relationship In Gabrielle Lord`s Lethal Factor

open access: yesLingua Cultura, 2007
Jenis karya sastra cerita detektif bukan hal baru dalam kesusastraan Australia. Salah satu penulis cerita detektif, Gabrielle Lord, menampilkan masalah yang tidak pernah diangkat oleh penulis lainnya, yaitu masalah hubungan keluarga.
Ruth Sri Kinanti
doaj   +5 more sources

Screening inhibitors of anthrax lethal factor [PDF]

open access: yesNature, 2002
The disease anthrax is caused by lethal factor, an enzyme component of the toxin produced by the spore-forming bacterium Bacillus anthracis. Here we describe substrate molecules for this factor that offer a means for high-throughput screening of potential inhibitors for use in anthrax treatment.
TONELLO, FIORELLA   +4 more
openaire   +6 more sources

CD4+ T cells targeting dominant and cryptic epitopes from Bacillus anthracis Lethal Factor [PDF]

open access: yesFrontiers in Microbiology, 2016
Anthrax is an endemic infection in many countries, particularly in the developing world. The causative agent, Bacillus anthracis, mediates disease through the secretion of binary exotoxins.
Stephanie eAscough   +11 more
doaj   +2 more sources

An immune-adrenergic pathway induces lethal levels of platelet-activating factor in mice [PDF]

open access: yesCommunications Biology
Acute immune responses with excess production of cytokines, lipid/chemical mediators, or coagulation factors, often result in lethal damage. In addition, the innate immune system utilizes multiple types of receptors that recognize neurotransmitters as ...
Shuto Tanaka   +14 more
doaj   +3 more sources

Lethal Factor and Anti-Protective Antigen IgG Levels Associated with Inhalation Anthrax, Minnesota, USA [PDF]

open access: yesEmerging Infectious Diseases, 2014
Bacillus anthracis was identified in a 61-year-old man hospitalized in Minnesota, USA. Cooperation between the hospital and the state health agency enhanced prompt identification of the pathogen.
Mark D. Sprenkle   +9 more
doaj   +2 more sources

Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome. [PDF]

open access: yesPLoS Pathogens, 2012
NOD-like receptor (NLR) proteins (Nlrps) are cytosolic sensors responsible for detection of pathogen and danger-associated molecular patterns through unknown mechanisms.
Jonathan L Levinsohn   +8 more
doaj   +2 more sources

Chimeric Antibody Engineering Against Bacillus anthracis Lethal Toxin: Neutralization Efficacy and Mechanism of Action [PDF]

open access: yesToxins
Bacillus anthracis has three main virulence factors: an extracellular capsule and two binary toxins (lethal toxin—consists of a lethal factor and a protective antigen, and edema toxin—consists of an edema factor and a protective antigen).
Olga V. Kalmantaeva   +7 more
doaj   +2 more sources

Rational Drug Designing Strategies and Inhibitor Optimization: Anthrax Lethal Toxin Factor [PDF]

open access: yesInternational Journal Bioautomation, 2012
Anthrax toxin protein protective antigen, edema factor and lethal factor are secreted by Bacillus anthracis bacteria causes several adverse effects on human as well as on ruminant animals and considered as serious biological weapons. Lethal toxin protein
Pawan Kumar Jayaswal   +2 more
doaj   +1 more source

Prospects for the use of Bacillus anthracis toxin in cancer therapy

open access: yesВетеринария сегодня, 2022
Cancer is one of the major causes of death in pet animals and humans worldwide. The contraindications and side effects associated with conventional cancer therapies heighten the importance of research aimed at finding new ways to combat cancer.
A. P. Rodionov   +3 more
doaj   +1 more source

Anthrax Toxin Detection: From In Vivo Studies to Diagnostic Applications

open access: yesMicroorganisms, 2020
Anthrax toxins are produced by Bacillus anthracis throughout infection and shape the physiopathogenesis of the disease. They are produced in low quantities but are highly efficient.
Jean-Nicolas Tournier   +1 more
doaj   +1 more source

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