Results 241 to 250 of about 988,812 (316)

Synthetic Particulate Subunit Vaccines Co‐Delivering Multiple Antigens Induce Protective Immunity Against Melioidosis

Advanced NanoBiomed Research, EarlyView.
Engineered endotoxin‐free Escherichia coli were used to assemble poly(3‐hydroxybutyrate) (PHB) biopolymer particles displaying multiple conserved Burkholderia pseudomallei antigens via PhaC‐mediated surface presentation. Following formulation with poly(I:C), the particulate vaccines induced antigen‐specific humoral and cellular immune responses ...
Md. Tanvir Kabir, Shuxiong Chen, Justine B. Bendo, Ashley Johnson, Aleksandra W. Debowski, Mitali Sarkar‐Tyson, Bernd H. A. Rehm   +6 more
wiley   +1 more source

Induction of Methuosis in Breast Cancer Stem Cells by a Cobalt(III) Complex Evokes Immunotherapeutic Response

Angewandte Chemie, EarlyView.
Cancer stem cells (CSCs) drive metastasis, relapse and resist conventional apoptosis‐inducing chemotherapies. We report a cobalt(III)‐cyclam complex with pyrene and diflunisal moieties that reduces the viability of breast CSCs at low micromolar concentrations.
Jiaxin Fang, Sijie Wen, Xiao Feng, Hao Ren, Kuldip Singh, Haihua Xiao, Lingpu Zhang, Kogularamanan Suntharalingam   +7 more
wiley   +2 more sources

Saxiphilin functions as a toxin sponge protein that counteracts the effects of saxitoxin poisoning. [PDF]

Nat Commun
Nixon SA, Zakrzewska S, Jang S, Huang K, Bara A, Chen Z, Goss DR, Park ER, Du Bois J, Minor DL.   +9 more
europepmc   +1 more source

Role of p38_alpha/beta MAP Kinase in Cell Susceptibility to Clostridium sordellii Lethal Toxin and Clostridium difficile Toxin B. [PDF]

Toxins (Basel), 2016
Schelle I, Bruening J, Buetepage M, Genth H.   +3 more
europepmc   +1 more source

Cutting Edge: Resistance to Bacillus anthracis Infection Mediated by a Lethal Toxin Sensitive Allele of Nalp1b/Nlrp1b

Journal of Immunology, 2009
Jill K. Terra, C. Cote, Bryan France, A. Jenkins, J. Bozue, S. Welkos, S. LeVine, K. Bradley   +7 more
semanticscholar   +1 more source

Expression of Nlrp1b Inflammasome Components in Human Fibroblasts Confers Susceptibility to Anthrax Lethal Toxin

Infection and Immunity, 2009
Kuo-Chieh Liao, J. Mogridge
semanticscholar   +1 more source

Ultrapotent neutralization of Bacillus anthracis toxin by a human antibody via blockade of PA oligomerization. [PDF]

PLoS Pathog
Wang Q, Fang T, Song Z, Huang X, He S, Li T, Li J, Chi X, Fan P, Yu C.   +9 more
europepmc   +1 more source

Difference in Mono-O-Glucosylation of Ras Subtype GTPases Between Toxin A and Toxin B From Clostridioides difficile Strain 10463 and Lethal Toxin From Clostridium sordellii Strain 6018. [PDF]

Front Microbiol, 2018
Genth H, Junemann J, Lämmerhirt CM, Lücke AC, Schelle I, Just I, Gerhard R, Pich A.   +7 more
europepmc   +1 more source

Nature's antivenom: Combinations of conserved rattlesnake serum metalloproteinase inhibitors block the lethal action of viper venoms. [PDF]

Proc Natl Acad Sci U S A
Carroll SB, Ukken FP, Ayinuola YA, Escalona L, Suntravat M, Sanchez EE.   +5 more
europepmc   +1 more source

Misuse of botulinum toxin is potentially lethal

BMJ, 2006
openaire   +2 more sources