Results 101 to 110 of about 6,250 (152)

Efficacy of melatonin and letrozole combination therapy compared to letrozole alone in the treatment of symptomatic endometrioma in infertile women [PDF]

Background: Endometriosis is an estrogen-driven inflammatory condition involving endometrial tissue growth outside the uterus. Letrozole, an aromatase inhibitor, lowers estrogen levels to reduce pain and lesion size.
Banu, Jesmine, Ishrat, Shakeela, Jahan, Nishat, Khatun, M. Sumyara, Islam, M. Ariful, Islam, Tahmida, Islam, Aminul, Deeba, Farzana   +7 more
core   +1 more source

Cognitive function in postmenopausal women receiving adjuvant letrozole or tamoxifen for breast cancer in the BIG 1-98 randomized trial

, 2010
Cognitive function in postmenopausal women receiving letrozole or tamoxifen as adjuvant endocrine treatment was compared during the fifth year of treatment in a substudy of the BIG 1-98 trial.
Thürlimann, Beat, Gelber, Richard D., Coates, Alan, Coates, Alan S., Ribi, Karin, Coates, Alan S, Gelber, Richard, Phillips, Kelly-Anne, Harvey, Vernon, Cardoso, Fatima, Thuerlimann, Beat, Price, Karen N, Bernhard, Jürg, Bernhard, Juerg, Price, Karen N., Sun, Zhuoxin, Gelber, Richard D, Stephens, Alisa, Thompson, Alastair, Goldhirsch, Aron, Pagani, Olivia   +20 more
core   +1 more source

Ribociclib with letrozole vs letrozole alone in elderly patients with hormone receptor-positive, HER2-negative breast cancer in the randomized MONALEESA-2 trial

, 2017
Determine the efficacy and safety of first-line ribociclib plus letrozole in elderly patients with HR+, HER2- advanced breast cancer. 668 postmenopausal women with HR+, HER2- advanced breast cancer and no prior systemic therapy for advanced disease were ...
Bachelot, Thomas, Hart, Lowell L, Alba, Emilio, Favret, Anne M, Erdkamp, Frans, Germa, Caroline, Anne M. Favret, Souami, Farida, Michelle Miller, Santosh Sutradhar, Erik Wist, Wist, Erik, Miller, Michelle, Emilio Alba, Sonke, Gabe S, Gabe S. Sonke, Sutradhar, Santosh, Mario Campone, Frans Erdkamp, Lowell L. Hart, Caroline Germa, Hegg, Roberto, Jakobsen, Erik, Burris, Howard A, Paul Wheatley-Price, Verma, Sunil, Roberto Hegg, Sunil Verma, Erik Jakobsen, Wheatley-Price, Paul, Wolfgang Janni, Thomas Bachelot, Janni, Wolfgang, Farida Souami, Howard A. Burris, Campone, Mario, Cristian Villanueva, Villanueva, Cristian   +37 more
core   +1 more source

Letrozole induced Necrotizing Cutaneous Vasculitis: A Rare Entity

Clinical Dermatology Review
Cutaneous small vessel vasculitis (CSVV) could be due to varied etiologies of which drug induced CSVV is a prime cause. It commonly presents as purpura but necrotizing lesions can be an uncommon presentation of the disease.
Liza Mohapatra, Soumya Surath Panda, Manoj Kumar Nayak, Kallolinee Samal   +3 more
doaj   +1 more source

A randomized controlled trial comparing combination of letrozole and clomiphene citrate or letrozole alone for ovarian stimulation in infertile women

Journal of Family Medicine and Primary Care
Introduction: Infertility is defined by failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse. Unexplained infertility was often treated with superovulation by using clomiphene, letrozole, or gonadotropins in a ...
Anamika Kumari, Mona Asnani, Anjoo Agarwal, Renu Singh, Smriti Agrawal   +4 more
doaj   +1 more source

Preparation of UiO-66 loaded Letrozole nano-drug delivery system: enhanced anticancer and apoptosis activity

AMB Express
The use of drug delivery systems in targeting and achieving the targeting of drugs in treating diseases, especially cancer, has attracted the attention of researchers. Letrozole is one of the drugs for the treatment of breast cancer.
Maryam Ronaghi, Ramtin Hajibeygi, Reza Ghodsi, Akram Eidi, Ronak Bakhtiari   +4 more
doaj   +1 more source

Individualisation of the Dose of Letrozole for Ovulation Induction in Infertile Women with Polycystic Ovary Syndrome Based on Clinical and Ultrasonography Criteria: A Cohort Study

Journal of Human Reproductive Sciences
Background: Conventionally, letrozole for ovulation induction (OI) in polycystic ovary syndrome (PCOS) is started at a dose of 2.5 mg, which is gradually escalated depending on the follicular response.
Pratyasha Peepal, Padmalaya Thakur, Anubhuti Patel, Jyotiranjan Sahoo, Sujata Pradhan, Manisha Sahu   +5 more
doaj   +1 more source

Letrozole and clomiphene versus letrozole alone for ovulation induction in women with PCOS: a systematic review and meta-analysis [PDF]

Objective: We aimed to compare the efficacy and safety of letrozole and clomiphene versus letrozole alone for ovulation induction in patients with Polycystic Ovary Syndrome (PCOS).
Karine Eskandar, Juliana Almeida Oliveira, Andrea Mora de Marco Novellino, Sandro Augusto Ribeiro, Ana Isabela de Araujo Zotti, Yasmin Jardim Meirelles Dias, Matheus Pedrotti Chavez   +6 more
core   +2 more sources

Letrozole removal resulted in resumption of estrous cycling.

, 2019
Estrous cycling was evaluated in placebo and letrozole-treated female mice via vaginal cytology. Vaginal smears were collected during weeks 4–5 (Pre; n = 6 placebo, n = 10 letrozole) and during weeks 10–11 (Post; n = 6 placebo, n = 8 letrozole ...
Bryan S. Ho (7444598), Lillian Sau (6468299), Scott T. Kelley (7444601), Varykina G. Thackray (7444604), Pablo Arroyo (316123)   +4 more
core   +1 more source

Letrozole::advancing hormone therapy in breast cancer

, 2012
Letrozole is a type 2 aromatase inhibitor, which reduces availability of estrogen in postmenopausal women, thereby decreasing its ability to stimulate breast cancer cells.
Armstrong, A.C., Wardley, A.M., Lee, R.J.; id_orcid   +2 more
core   +1 more source