Results 91 to 100 of about 22,913 (185)

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, Volume 13, Issue 61, 3 November 2026.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Letrozole Potentiates Mitochondrial and Dendritic Spine Impairments Induced by β Amyloid

Journal of Aging Research, 2013
Reduced estrogens, either through aging or postsurgery breast cancer treatment with the oral nonsteroidal aromatase inhibitor letrozole, are linked with declined cognitive abilities.
P. K.-Y. Chang, S. Boridy, R. A. McKinney, D. Maysinger   +3 more
doaj   +1 more source

Development, Optimization, and Physicochemical Characterization of Fluorescent Carbon Dot‐Ginkgo biloba Extract Co‐Loaded Niosomes for Future Neurological Disease‐Relevant Evaluation

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Carbon dot–Ginkgo biloba–loaded niosomal nanovesicles are fabricated via rotary evaporation, probe sonication, and centrifugation to co‐deliver natural neuroprotective agents to the brain. The optimized system shows high encapsulation, sustained release, and excellent biocompatibility, suggesting a promising nano‐vesicular platform for Alzheimer's ...
Yasaman Mohammadi, Mohammad Saied Salehi, Ehsan Heidari, Mina Ebrahimi, Nahid Ashjazadeh   +4 more
wiley   +1 more source

Effects of letrozole on bone biomarkers and femur fracture in female rats

, 2009
We aimed to investigate the effects of the aromatase inhibitor letrozole on femur fracture and serum levels of alkaline phosphatase (ALP), calcium and phosphate in female rats.
Kelestemur, M. H., Kelestemur, M.H., Yilmaz, BAYRAM, Kelestemur, Mehmet Halidun, Aydin, M., Akin, E., Kutlu, S., Yilmaz, B., Yonden, Z., Alcin, E., B. Yilmaz, M. Aydin, E. Alcin, Z. Yonden, M. H. Kelestemur, S. Kutlu   +15 more
core   +1 more source

The Success of Ovulation Induction with Letrozole and Gonadotropins in Obese and Nonobese Women: A Study from a Tertiary Center

, 2022
BACKGROUND: Letrozole, an aromatase inhibitor, is suggested as a first-line drug for ovulation induction in women with polycystic ovary syndrome (PCOS) especially in obese women.
Jaju, Sanjay, Gowri, Vaidyanathan, Al Khaduri, Maha, Al-Amri, Arwa, Almamari, Thikra Mohammed Abdulrahman, Vaidyanathan Gowri, Arwa Al-Amri, Thikra Mohammed Abdulrahman Almamari, Sanjay Jaju, Maha Al Khaduri   +9 more
core   +1 more source

Foot drop in generalized herpes zoster: L5‑predominant polyradiculitis as a rare complication – a case report

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Anna Malfertheiner, Alexander Mensch, Burkhard Kreft   +2 more
wiley   +1 more source

Letrozole co-treatment in an antagonist protocol for overweight women undergoing IVF treatment: a retrospective study

BMC Pregnancy and Childbirth
Background Overweight women undergoing IVF treatment have lower success rates. Letrozole, an aromatase inhibitor, has been used as an adjunct for IVF treatment, but its specific effects in overweight women have not been investigated.
Jing Lin, Fenglu Wu, Yanwen Zhu, Bian Wang, Zhengjun Cao, Jiaying Lin   +5 more
doaj   +1 more source

Letrozole sensitizes breast cancer cells to ionizing radiation. [PDF]

, 2005
INTRODUCTION: Radiotherapy (RT) is considered a standard treatment option after surgery for breast cancer. Letrozole, an aromatase inhibitor, is being evaluated in the adjuvant setting.
Dean B Evans, Larbouret, C., Cunat, S., Pujol, P., Evans, Dean, B., Ozsahin, Mahmut, Gilles Romieu, Mahmut Ozsahin, Pèlegrin, A., David Azria, Gourgou, S., Pujol, Pascal, Pèlegrin, André, Larbouret, Christel, Evans, Dean,, Gourgou, Sophie, Christel Larbouret, Azria, D., Pascal Pujol, Martineau, Pierre, Romieu, Gilles, Azria, David, Severine Cunat, Evans, D.B., Sophie Gourgou, Ozsahin, M., Andre Pèlegrin, Martineau, P., Pierre Martineau, Romieu, G., Cunat, Severine   +30 more
core   +2 more sources

The new WHO infertility guideline: A universal right to equitable, evidence‐based fertility care

International Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 526-529, November 2026.
Abstract The WHO ‘Guideline for the prevention, diagnosis and treatment of infertility’ heralds a significant global shift towards recognizing infertility as a medical condition requiring prevention, diagnosis, treatment and policy support. This recognition is vital for the one in six people with infertility worldwide and for policymakers trying to ...
M. Louise Hull, Kurt T. Barnhart, Nikhil C. Purandare, Aparna Sridhar, E. Göknur Topçu, Scott M. Nelson, on behalf of the FIGO REI committee, M. Louise Hull, Nikhil Purandare, Elif G. Topcu, Jackline Akol, Akira Iwase, Ivonne Diaz Yamal, Haroon Latif, Pablo Diaz Spíndola, Sunita R. Tandulwadkar, Virginia Chaquiriand, Ying Cheong, Scott Nelson, Kurt Barnhart   +19 more
wiley   +1 more source

A comparison of letrozole and anastrozole followed by letrozole in breast cancer patients

, 2015
Potchavit Aphinives, Damnern Vachirodom, Chaiyut Thanapaisal, Dhanes Rangsrikajee, Ongart SomintaraDepartment of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandBackground: We previously studied the noninferiority of anastrozole ...
Thanapaisal C, Rangsrikajee D, Somintara O, Vachirodom D, Aphinives P   +4 more
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