Results 61 to 70 of about 20,646 (210)

The Predictive Value of the Tumor‐Stroma Ratio for Neoadjuvant Endocrine Therapy in Hormone Receptor‐Positive Breast Cancer

International Journal of Cancer, Volume 159, Issue 4, Page 1056-1067, 15 August 2026.
Neoadjuvant endocrine therapy (NET) can help prevent metastases and improve survival in patients with hormone receptor‐positive (HR+) breast cancer. Identifying which HR+ patients will benefit from NET, however, remains challenging. Here, in a patient cohort in the Netherlands, the authors evaluated tumor‐stroma ratio (TSR) and magnetic resonance ...
Layla Andour, Sophie C. Hagenaars, Anne Florine de Groot, Elly M. M. Krol‐Warmerdam, Judith R. Kroep, Hans Marten Hazelbag, Gerrit‐Jan Liefers, Marieke E. Straver, Wilma E. Mesker   +8 more
wiley   +1 more source

Long‐term benefit from adjuvant tamoxifen therapy for ER+ HER2− breast cancer by PR positivity

International Journal of Cancer, Volume 159, Issue 2, Page 450-459, 15 July 2026.
What's new? Tamoxifen is a cornerstone of endocrine therapy for estrogen receptor (ER)‐positive/human epidermal growth factor receptor 2 (HER2)‐negative breast cancer. Its long‐term benefits, however, may vary by progesterone receptor (PR) status. Here, using data from the Stockholm tamoxifen trials, the authors evaluated whether PR expression predicts
Anna E. Nordenskjöld, Magdalena Ríos‐Romero, Huma Dar, Tommy Fornander, Gizeh Perez‐Tenorio, Helena Fohlin, Olle Stål, Julia Tutzauer, Linda S. Lindström   +8 more
wiley   +1 more source

Comparison of the Effect of Letrozole and Misoprostol versus Misoprostol Alone on First Trimester Abortion [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2023
Background and Objective: The need to perform an abortion in the first three months of pregnancy with an effective and safe drug therapy is more important than other methods.
M Mokhtari, S Sadeghi
doaj  

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, Volume 159, Issue 2, Page 460-466, 15 July 2026.
What's new? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Letrozole removal resulted in fewer differentially abundant bacterial genera in placebo versus letrozole mice.

, 2019
DESeq2 differential abundance results were expressed as log2 fold change to compare placebo- and letrozole-treated female mice before (A) and after pellet removal (B).
Bryan S. Ho (7444598), Lillian Sau (6468299), Scott T. Kelley (7444601), Varykina G. Thackray (7444604), Pablo Arroyo (316123)   +4 more
core   +1 more source

Letrozole therapy alone or in sequence with tamoxifen in women with breast cancer [PDF]

, 2009
BACKGROUND: The aromatase inhibitor letrozole, as compared with tamoxifen, improves disease-free survival among postmenopausal women with receptor-positive early breast cancer.
Gelber RD, Thürlimann B, Massa E, Mantovani G, Price KN, Forbes JF, Giobbie-Hurder A, Mouridsen H, Paridaens R, Smith I, Goldhirsch A, on behalf of BIG 1-98 Collaborative Group, Mauriac L, Coates AS, Regan MM   +14 more
core   +2 more sources

Ovulation rates in a stair-step protocol with Letrozole vs clomiphene citrate in patients with polycystic ovarian syndrome

Contraception and Reproductive Medicine, 2019
Purpose To compare ovulation rates between Letrozole and Clomiphene Citrate (CC) using a stair-step protocol to achieve ovulation induction in women with Polycystic Ovarian Syndrome (PCOS). Methods This is a retrospective cohort of predominantly Hispanic
S. Thomas, I. Woo, J. Ho, T. Jones, R. Paulson, K. Chung, K. Bendikson   +6 more
doaj   +1 more source

In Vitro Fertilization is Essential Healthcare for Patients With Rheumatic Disease

ACR Open Rheumatology, Volume 8, Issue 7, July 2026.
Infertility presents a profound physical, emotional, and financial burden, particularly for rheumatology patients who often face substantial barriers to family building. The 2024 Alabama Supreme Court ruling in LePage v. Center for Reproductive Medicine equating embryo destruction with wrongful death introduced new legal uncertainties, sparking ...
Amanda Moyer, Catherine A. Sims, Rosalind Ramsey‐Goldman, Solmaz Chamanara, Cuoghi Edens   +4 more
wiley   +1 more source

Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome [Erratum]

, 2017
Hajishafiha M, Dehghan M, Kiarang N, et al. Combined letrozole and clomiphene versus letrozole and clomiphene alone in infertile patients with polycystic ovary syndrome. Drug Design, Development and Therapy.
Navid Shayegh S, Ghasemi-Rad M, Dehghan M, Sadegh-Asadi N, Hajishafiha M, Kiarang N   +5 more
core  

Comparison of ovulation induction with letrozole plus dexamethasone and letrozole alone in infertile women with polycystic ovarian disease: An RCT

, 2020
Background: Infertility is characterized by the inability to obtain a successful pregnancy after 6 months or more with unprotected and regular intercourse. In developing countries, the incidence of infertility is 2%.
Farzaneh, Farahnaz, Afshar, Fatemeh
core   +1 more source