Results 41 to 50 of about 6,250 (152)

Letrozole step-up protocol for ovulation induction in infertile women with polycystic ovary syndrome – a randomized controlled trial

Middle East Fertility Society Journal
Background Polycystic ovary syndrome (PCOS) is the largest single cause of anovulatory infertility. Letrozole, an aromatase inhibitor, has been regarded as the first-line drug for ovulation induction in PCOS patients.
Pushpita Sharmin, Amitun Nessa, Abanti Ghosh, Lubna Jahan, Mst. Sumyara Khatun, Shakeela Ishrat   +5 more
doaj   +1 more source

Effects of Lipoherb with Metformin on Metabolic Parameters and Sex Hormones in Rats with Polycystic Ovary Syndrome

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2023
Introduction: The purpose of the present study was comparing the effects of Lipoherb with metformin on metabolic changes and sex hormones of rats with polycystic ovary syndrome Methods: Thirty female Wistar rats were divided into 5 groups (n=6).
Fatemeh Tavakoli, Azadeh Emami, Behrooz Heydari, Mohsen Abbasi, Mohammad Ebrahim Rezvani   +4 more
doaj  

The Differences of Folliculogenesis between Treated with Letrozole and Letrozole-Electroacupuncture in Women with Polycystic Ovary Syndrome [PDF]

, 2020
Background: Polycystic Ovary Syndrome (PCOS) is an endocrine disorder that most often causes infertility. It occurs due to the failure of folliculogenesis, thus causing non-ovulation.
Budihastuti, Uki Retno, Yulyanti, Yulyanti, Melinawati, Eriana, Sulistyowati, Sri, Nurwati, Ida   +4 more
core   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source

Effect of letrozole doses on clinical pregnancy rates in polycystic ovary syndrome: a systematic review and network meta-analysis

Gynecological Endocrinology
Letrozole, an aromatase inhibitor, is commonly used for ovulation induction in patients with polycystic ovary syndrome (PCOS). However, the effect of different doses of letrozole on pregnancy outcomes remains controversial.
Yanting Sun, Jun Wang, Guofeng Chen
doaj   +1 more source

The aromatase inhibitor letrozole enhances the effect of doxorubicin and docetaxel in an MCF7 cell line model [PDF]

BioDiscovery, 2012
<p>Introduction: Post-menopausal women with estrogen receptor (ER) positive breast cancer receive adjuvant chemotherapy and endocrine therapy sequentially since tamoxifen may antagonise the cytotoxicity of chemotherapy drugs.
Mary O’Neill, Fiona E.M. Paulin, Julie Vendrell, Clinton W. Ali, Alastair M. Thompson   +4 more
doaj   +3 more sources

The new WHO infertility guideline: A universal right to equitable, evidence‐based fertility care

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract The WHO ‘Guideline for the prevention, diagnosis and treatment of infertility’ heralds a significant global shift towards recognizing infertility as a medical condition requiring prevention, diagnosis, treatment and policy support. This recognition is vital for the one in six people with infertility worldwide and for policymakers trying to ...
M. Louise Hull, Kurt T. Barnhart, Nikhil C. Purandare, Aparna Sridhar, E. Göknur Topçu, Scott M. Nelson, on behalf of the FIGO REI committee, M. Louise Hull, Nikhil Purandare, Elif G. Topcu, Jackline Akol, Akira Iwase, Ivonne Diaz Yamal, Haroon Latif, Pablo Diaz Spíndola, Sunita R. Tandulwadkar, Virginia Chaquiriand, Ying Cheong, Scott Nelson, Kurt Barnhart   +19 more
wiley   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Pregnancy And Neonatal Outcomes Of hMG Stimulation With Or Without Letrozole In Endometrial Preparation For Frozen–Thawed Embryo Transfer In Ovulatory Women: A Large Retrospective Cohort Study

Drug Design, Development and Therapy, 2019
Jiaying Lin,* Ningling Wang,* Jialv Huang, Renfei Cai, Yong Fan, Yanping Kuang, Yun Wang Department of Assisted Reproduction, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of ...
Lin J, Wang N, Huang J, Cai R, Fan Y, Kuang Y, Wang Y   +6 more
doaj  

Off-label letrozole for tubal pregnancy monotherapy is not an alternative to methotrexate: a prospective cohort study

Ginekologia Polska
OBJECTIVES: Inhibition of estradiol production by letrozole may interfere with physiological effects of progesterone necessary to maintain the pregnancy.
Iwona M. Gawron, Dorota Babczyk, Robert Jach   +2 more
doaj   +1 more source