Results 41 to 50 of about 22,913 (185)

Concomitant tamoxifen or letrozole for optimal oocyte yield during fertility preservation for breast cancer: the TAmoxifen or Letrozole in Estrogen Sensitive tumors (TALES) randomized clinical trial [PDF]

, 2021
PURPOSE: To determine whether concomitant tamoxifen 20 mg with gonadotropins (tamoxifen-gonadotropin) versus letrozole 5 mg with gonadotropins (letrozole-gonadotropin) affects mature oocyte yield. METHODS: Open-label, single-institution, randomized trial.
Dolezal, Milana, Cedars, Marcelle I, Ribeiro, Salustiano, Wald, Kaitlyn, Chien, A. Jo, McCulloch, Charles E, Cedars, Marcelle I., Rosen, Mitchell, Juarez-Hernandez, Flor, Mok-Lin, Evelyn, McCulloch, Charles E., Chien, A Jo, Letourneau, Joseph, Wang, Ange, Kaitlyn Wald, Charles E. McCulloch, Mitchell Rosen, Flor Juarez-Hernandez, A. Jo Chien, Evelyn Mok-Lin, Marcelle I. Cedars, Joseph Letourneau, Milana Dolezal, Ange Wang, Salustiano Ribeiro   +24 more
core   +1 more source

Cysteine–Cysteine Motif Chemokine Receptor 5 Expression in Letrozole-Induced Polycystic Ovary Syndrome Mice

, 2021
Polycystic ovary syndrome (PCOS), which affects 5–10% of women of reproductive age, is associated with reproductive and metabolic disorders, such as chronic anovulation, infertility, insulin resistance, and type 2 diabetes.
Chi-Hong Ho, Peng-Hui Wang, Luen-Kui Chen, Pin-Shiou Liu, Kuo-Hu Chen, Kok-Min Seow, Chi-Chang Juan, Chien-Wei Chen, Jiann-Loung Hwang   +8 more
core   +1 more source

Comparison of ovulation induction with letrozole plus dexamethasone and letrozole alone in infertile women with polycystic ovarian disease: An RCT [PDF]

, 2020
Background: Infertility is characterized by the inability to obtain a successful pregnancy after 6 months or more with unprotected and regular intercourse. In developing countries, the incidence of infertility is 2%.
Farzaneh, Farahnaz, Afshar, Fatemeh
core   +1 more source

A prospective randomized trial comparing the efficacy of Letrozole and Clomiphene citrate in induction of ovulation in polycystic ovarian syndrome

Journal of Human Reproductive Sciences, 2012
Objectives: To compare the efficacy of letrozole and clomiphene citrate (CC) in patients of anovulatory polycystic ovarian syndrome (PCOS) with infertility.
Kallol Kumar Roy, Jinee Baruah, Shilpa Singla, Jai Bhagwan Sharma, Neeta Singh, Sunesh Kumar Jain, Manu Goyal   +6 more
doaj   +1 more source

Effect of letrozole and raloxifene on in vitro human endometrial stromal cells [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Letrozole and raloxifene are used in female reproductive disease. They have special properties and side-effects. This study was performed with aim to compare the in vitro effects of letrozole and raloxifene on human endometrial stromal ...
Maryam Pourheydar, Zahra Rashidi, Mozafar Khazaei   +2 more
doaj   +1 more source

Coenzyme q10 and letrozole versus letrozole alone for ovulation induction in polycystic ovary syndrome [PDF]

, 2022
Background: Polycystic ovary syndrome (PCOS) is the largest single cause of anovulatory infertility. PCOS is associated with oxidative stress. Coenzyme q10 (Coq10) is an antioxidant that protects the mitochondria from damage caused by either insulin ...
Halder, Suravi, Ishrat, Shakeela, Amir, Mumtahena, Nasrin, Ivy, Rahman, Farzana, Kamruzzaman, Mohammad   +5 more
core   +1 more source

Does daily co administration of gonadotropins and letrozole during the ovarian stimulation improve IVF outcome for poor and sub optimal responders?

Journal of Ovarian Research, 2020
Background Co-administration of letrozole during the first 5 days of ovarian stimulation was suggested to improve IVF outcomes in poor responders.
Moran Shapira, Raoul Orvieto, Oshrit Lebovitz, Ravit Nahum, Adva Aizer, Aliza Segev-Zahav, Jigal Haas   +6 more
doaj   +1 more source

Letrozole removal resulted in fewer differentially abundant bacterial genera in placebo versus letrozole mice.

, 2019
DESeq2 differential abundance results were expressed as log2 fold change to compare placebo- and letrozole-treated female mice before (A) and after pellet removal (B).
Bryan S. Ho (7444598), Lillian Sau (6468299), Scott T. Kelley (7444601), Varykina G. Thackray (7444604), Pablo Arroyo (316123)   +4 more
core   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

Advanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou, Kristine J. Fernandez, Min Li Huang, Ewan K. A. Millar, Claire Vennin, Leila Eshraghi, Tan Dat Timothy Lam, Victoria Lee, Nyah C. Brooks, Janett Stoehr, Cristian Guaman Mendez, Douglas Strathdee, David Stevenson, David Herrmann, Sandra O'Toole, Paul Timpson, Max Nobis, C. Elizabeth Caldon   +17 more
wiley   +1 more source

A comparative study of ovulation induction by clomiphene citrate vs letrozole [PDF]

New Indian Journal of OBGYN
Objectives: The present study was conducted to compare ovulation induction by clomiphene citrate and letrozole in women with ovulatory dysfunction. Methodology: In this open label comparative randomized clinical trial, patients aged 20 to 40 years with
Hemant Deshpande, Madhukar Shinde, Neha Ellath, Vidya Gaikwad   +3 more
doaj   +1 more source