Results 21 to 30 of about 22,913 (185)

Cost-utility analysis of Palbociclib + letrozole and ribociclib + letrozole versus Letrozole monotherapy in the first-line treatment of metastatic breast cancer in Iran using partitioned survival model

Health Economics Review, 2023
Background Palbociclib and Ribociclib are cyclin-dependent kinase 4/6 oral molecular inhibitors that have the potential to improve overall survival (OS), progression-free survival (PFS), and quality of life in patients with metastatic breast cancer (MBC).
Ali Darvishi, Rajabali Daroudi, Ali Akbar Fazaeli   +2 more
doaj   +1 more source

Effects of letrozole co-treatment on the cumulative live-birth rate among normal responders in gonadotropin-releasing hormone antagonist cycles

Frontiers in Medicine, 2022
Studies have shown that letrozole cotreatment can improve clinical outcomes in high and poor responders in GnRH-antagonist protocol. However, whether letrozole is also beneficial to normal responders is not known.
Shuyi Zhang, Fumei Gao, Min Fu, Huan Shen, Yanbin Wang, Hongjing Han   +5 more
doaj   +1 more source

Effect of Letrozole versus Clomiphene Citrate on Endometrial Receptivity and Peri follicular Vascularity in Infertile Women with Polycystic Ovarian Syndrome [PDF]

Zagazig University Medical Journal, 2023
Background: Polycystic ovarian syndrome is the most common endocrine problem in females with an incidence of (6 -10%) . The purpose of this study was to make acomparison between the effect of clomiphene citrate versus letrozole on the endometrial ...
ASMAA ELOSS, Amal El Saied, Azza Abd Elhameid, Entesar Mahdy   +3 more
doaj   +1 more source

Low dose-extended letrozole versus double dose-short letrozole protocol for ovulation induction in polycystic ovary syndrome [PDF]

, 2022
Background: Letrozole, an aromatase inhibitor has been regarded as the first line drug for ovulation induction in anovulatory PCOS patients because of its monofollicular growth and there is no chance of hyperstimulation by letrozole. Traditional protocol
Nazneen, Sohely, Banu, Jesmine, Ishrat, Shakeela, Jahan, Nishat, Rani, Chalontika, Akter, Sumaiya, Jahan, Shirin, Deeba, Farzana   +7 more
core   +1 more source

Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial [PDF]

, 2018
Background: In animal models of breast cancer, resistance to continuous use of letrozole can be reversed by withdrawal and reintroduction of letrozole.
Hitre, E, Colleoni, M, Chirgwin, J, Karlsson, P, Luo, W, Abdi, E, Thompson, A, Kamby, C, Graas, MP, Jerusalem, G, Simoncini, E, Aebi, S, Neven, P, et al., Loibl, S   +14 more
core   +2 more sources

Letrozole-induced endometrial preparation improved the pregnancy outcomes after frozen blastocyst transfer compared to the natural cycle: a retrospective cohort study

BMC Pregnancy and Childbirth, 2022
Background Letrozole treatment is considered an effective option in endometrial preparation for frozen embryo transfers in patients with ovulation disorders or irregular menstruation; however, the effectiveness of letrozole-induced endometrial ...
Kenji Ezoe, Junichiro Fukuda, Kazumi Takeshima, Kazunori Shinohara, Keiichi Kato   +4 more
doaj   +1 more source

Lapatinib in the Treatment of Hormone Receptor-Positive/ErbB2-Positive Breast Cancer [PDF]

, 2010
In women with estrogen receptor(ER)- and ErbB2(HER2)-positive breast cancer, a vicious cycle is established between ER mechanisms of action and the growth factor receptor network, leading to enhanced cell proliferation and endocrine resistance.
Bauerfeind, Ingo, Elling, Dirk, Heinemann, Volker   +2 more
core   +1 more source

Letrozole increases preantral follicle growth and decreases estradiol production without impairing follicle survival

Journal of Ovarian Research, 2022
Background Letrozole has been reported to be effective in treating anovulation, preventing ovarian hyperstimulation syndrome (OHSS), and retrieving oocytes in breast cancer patients.
Fukiko Kasuga-Yamashita, Tsuyoshi Baba, Sachiko Nagao, Yuya Fujibe, Miyuki Morishita, Yoshika Kuno, Tasuku Mariya, Hiroyuki Honnma, Toshiaki Endo, Tamotsu Kiya, Tsuyoshi Saito   +10 more
doaj   +1 more source

The Differences of Folliculogenesis between Treated with Letrozole and Letrozole-Electroacupuncture in Women with Polycystic Ovary Syndrome [PDF]

, 2020
Background: Polycystic Ovary Syndrome (PCOS) is an endocrine disorder that most often causes infertility. It occurs due to the failure of folliculogenesis, thus causing non-ovulation.
Budihastuti, Uki Retno, Yulyanti, Yulyanti, Melinawati, Eriana, Sulistyowati, Sri, Nurwati, Ida   +4 more
core   +1 more source

Whether Letrozole could reduce the incidence of early ovary hyperstimulation syndrome after assisted reproductive technology? A systematic review and meta-analysis

Reproductive Health, 2020
Background Letrozole can significantly decrease the estrogen level, and has been administrated to prevent the incidence of early ovary hyperstimulation syndrome (OHSS).
Jing Zhao, Bin Xu, Xi Huang, Yi Yan, Yanping Li   +4 more
doaj   +1 more source