Results 11 to 20 of about 6,250 (152)

Letrozole for Female Infertility [PDF]

Frontiers in Endocrinology, 2021
Letrozole, an aromatase inhibitor that blocks estrogen synthesis by inhibiting the final step of the estrogen biosynthetic pathway, has been used in the applications of a wide range of infertility settings.
Ai-Min Yang, Na Cui, Yi-Fei Sun, Gui-Min Hao   +3 more
doaj   +2 more sources

Current evidence supporting "letrozole" for ovulation induction

Journal of Human Reproductive Sciences, 2013
Aromatase inhibitor "letrozole" was first introduced as a potential ovulation induction (OI) drug almost a decade back. Large number of studies has been published using letrozole for OI: In polycystic ovary syndrome (PCOS) women, clomiphene citrate (CC ...
Sujata Kar
doaj   +2 more sources

Cost-effectiveness Analysis of Ribociclib plus Letrozole versus Palbociclib plus Letrozole in the United Kingdom

Journal of Health Economics and Outcomes Research, 2019
# Objective To evaluate the cost-effectiveness of ribociclib plus letrozole versus palbociclib plus letrozole in post-menopausal women with hormone receptor positive (HR+) and human epidermal growth receptor 2 negative (HER2-) advanced breast cancer from
Gaurav Suri, David Chandiwana, Adam Lee, Rohit Mistry   +3 more
doaj   +2 more sources

Letrozole versus

Middle East Fertility Society Journal, 2016
Objective: To evaluate the efficacy of letrozole in the endometrial preparation of vitrified–warmed embryo transfer cycles and to compare it to the hormonal preparation with estradiol valerate and progesterone study.
Hoda Sibai, Ahmed El Husseiny, Eman Elgindy   +2 more
doaj   +2 more sources

Letrozole-loaded nonionic surfactant vesicles prepared via a slurry-based proniosome technology: Formulation development and characterization [PDF]

, 2020
Slurry-based Letrozole (LTZ)-loaded proniosomes were designed using sucrose or sorbitol as carriers and various ratios of cholesterol (CH) and Tween 80 (T80) as lipid composition.
Mohamed A. Elrayess (7956179), Nada Khudair (16673805), Mohammad Najlah (3397832), Abdelali Agouni (181926), Husam M. Younes (11884326), Abdelbary M. A. Elhissi (16654905)   +5 more
core   +7 more sources

Extended adjuvant intermittent letrozole versus continuous letrozole in postmenopausal women with breast cancer (SOLE): a multicentre, open-label, randomised, phase 3 trial [PDF]

, 2018
Background: In animal models of breast cancer, resistance to continuous use of letrozole can be reversed by withdrawal and reintroduction of letrozole.
Hitre, E, Colleoni, M, Chirgwin, J, Karlsson, P, Luo, W, Abdi, E, Thompson, A, Kamby, C, Graas, MP, Jerusalem, G, Simoncini, E, Aebi, S, Neven, P, et al., Loibl, S   +14 more
core   +2 more sources

Lapatinib in the Treatment of Hormone Receptor-Positive/ErbB2-Positive Breast Cancer [PDF]

, 2010
In women with estrogen receptor(ER)- and ErbB2(HER2)-positive breast cancer, a vicious cycle is established between ER mechanisms of action and the growth factor receptor network, leading to enhanced cell proliferation and endocrine resistance.
Bauerfeind, Ingo, Elling, Dirk, Heinemann, Volker   +2 more
core   +1 more source

Letrozole-induced endometrial preparation improved the pregnancy outcomes after frozen blastocyst transfer compared to the natural cycle: a retrospective cohort study

BMC Pregnancy and Childbirth, 2022
Background Letrozole treatment is considered an effective option in endometrial preparation for frozen embryo transfers in patients with ovulation disorders or irregular menstruation; however, the effectiveness of letrozole-induced endometrial ...
Kenji Ezoe, Junichiro Fukuda, Kazumi Takeshima, Kazunori Shinohara, Keiichi Kato   +4 more
doaj   +1 more source

Coenzyme q10 and letrozole versus letrozole alone for ovulation induction in polycystic ovary syndrome [PDF]

, 2022
Background: Polycystic ovary syndrome (PCOS) is the largest single cause of anovulatory infertility. PCOS is associated with oxidative stress. Coenzyme q10 (Coq10) is an antioxidant that protects the mitochondria from damage caused by either insulin ...
Halder, Suravi, Ishrat, Shakeela, Amir, Mumtahena, Nasrin, Ivy, Rahman, Farzana, Kamruzzaman, Mohammad   +5 more
core   +1 more source

Whether Letrozole could reduce the incidence of early ovary hyperstimulation syndrome after assisted reproductive technology? A systematic review and meta-analysis

Reproductive Health, 2020
Background Letrozole can significantly decrease the estrogen level, and has been administrated to prevent the incidence of early ovary hyperstimulation syndrome (OHSS).
Jing Zhao, Bin Xu, Xi Huang, Yi Yan, Yanping Li   +4 more
doaj   +1 more source