Results 121 to 130 of about 603,709 (398)

Effects of intraduodenal infusion of the branched-chain amino acid leucine on ad libitum eating, gut motor and hormone functions, and glycemia in healthy men.

American Journal of Clinical Nutrition, 2015
BACKGROUND Branched-chain amino acids (BCAAs), particularly leucine, act as nutrient signals regulating protein synthesis and degradation as well as glucose metabolism.
R. Steinert, Maria F Landrock, Sina S Ullrich, S. Standfield, B. Otto, M. Horowitz, C. Feinle-Bisset   +6 more
semanticscholar   +1 more source

Integrating Visible‐Light Photocatalysis and Enzymes for the Stereoselective Synthesis of Alcohols and Amines

Advanced Synthesis &Catalysis, EarlyView.
The integration between visible‐light photocatalysis and biocatalysis has the potential to greatly improve modern organic synthesis by combining the production of valuable synthetic intermediates under mild photochemical conditions with the high degree of stereoselectivity reached by enzymes. The review collects the recent efforts in the photoenzymatic
Stefano Parisotto, Cristina Prandi
wiley   +1 more source

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

Journal of Physiology, 2013
•  The branched‐chain amino acid (BCAA) leucine acts as both a ‘trigger’ for the initiation of protein synthesis, and as a substrate for newly synthesized protein.
D. Wilkinson, T. Hossain, D. Hill, B. Phillips, H. Crossland, J. Williams, P. Loughna, T. Churchward-Venne, L. Breen, Stuart M Phillips, T. Etheridge, J. Rathmacher, K. Smith, N. Szewczyk, P. Atherton   +14 more
semanticscholar   +1 more source

Selective Co‐Assembly of Water‐Soluble Conjugated Polyelectrolyte with Discernable Fluorescence Modulation for Antibiotic Detection

Advanced Sensor Research, EarlyView.
PQx‐Ph, a water‐soluble conjugated polyelectrolyte, enables rapid and selective fluorescence‐based detection of structurally distinct antibiotics via supramolecular assembly modulation. It achieves nanomolar sensitivity under mild conditions and preserves reliable sensing performance across NOM‐rich and biologically relevant water matrices, supporting ...
Hyena Ji, Yesica Fernanda Florez‐Villabona, Youngsun Kim, Yerim Kim, Yongju Kim, Seungyun Baik, Young Hun Seo, Sehoon Kim   +7 more
wiley   +1 more source

Experiments on the origin of molecular chirality by parity non-conservation during beta-decay [PDF]

Experiments are described to test a theory for the origin of optical activity wherein the longitudinally polarized electrons resulting from parity violation during radioactive beta decay, and their resulting circularly polarized Bremsstrahlung, might ...
Bonner, W. A.
core   +1 more source

Genetic mapping, synteny, and physical location of two loci for Fusarium oxysporum f. sp. tracheiphilum race 4 resistance in cowpea [Vignaunguiculata (L.) Walp]. [PDF]

, 2013
Fusarium wilt is a vascular disease caused by the fungus Fusariumoxysporum f.sp. tracheiphilum (Fot) in cowpea [Vignaunguiculata (L.) Walp]. In this study, we mapped loci conferring resistance to Fot race 4 in three cowpea RIL populations: IT93K-503-1 ...
Close, Timothy J, Ehlers, Jeffery D, Li, Guojing, Pottorff, Marti O, Roberts, Philip A   +4 more
core   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

Advanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak, Shivananda Kandagalla, Ramesh Sistla   +2 more
wiley   +1 more source

Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway. [PDF]

, 2017
Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established.
Dong, Weibing, Liu, Yunxia, Shao, Jing, Sun, Haipeng, Wang, Yibin, Zhou, Meiyi   +5 more
core   +2 more sources

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, EarlyView.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

The Effect of Beta-Hydroxy-Beta-MethylbutyrateSupplementation on Performance Adaptations Following ResistanceTraining in Young Males

Türk Spor ve Egzersiz Dergisi, 2019
The aim of this study was to examine the effects of 8 weeks beta-hydroxy-beta-methylbutyrate (HMB) supplementation with resistance training on some components of physical fitness and body composition in young males.
Farhad Rahmini-nia, Hani Haj Salimi
doaj   +1 more source