Results 131 to 140 of about 639,233 (341)

Leucine-Sensitive Hypoglycæmia [PDF]

Proceedings of the Royal Society of Medicine, 1970
G, Tevaarwerk, C, Lowy, M, Hartog, T R, Fraser   +3 more
openaire   +2 more sources

Hydrogelation via Supramolecular Copolymerization of Structural Water within Adaptive Metal–Organic Fibers

Advanced Materials, EarlyView.
Structural water is harnessed as an active co‐monomer to drive supramolecular polymerization in bulk water. Zinc(II) Salphen complexes confine water molecules to form hollow, metal–organic nanofibers that assemble into adaptive hydrogels with thermoresponsive mechanics and selective chiral recognition.
Merlin R. Stühler, Hesam Makki, Tarek Hilal, Debsena Chakraboty, Mathias Dimde, Kai Ludwig, Rainer Haag, Sabine Rosenfeldt, Dorothee Silbernagl, Andreas Schäfer, Alex J. Plajer   +10 more
wiley   +1 more source

Molecular‐Level Insights into Interfacial Adsorption Mechanisms of PFOA on Functional Dolomite Surfaces via AIMD and Spectroscopy

Advanced Materials Interfaces, EarlyView.
Perfluorooctanoic acid (PFOA), ab initio molecular dynamics (AIMD), density functional theory (DFT), Dolomite (DL), metal‐organic frameworks (MOFs), calcined modified dolomite (CDL), zero‐point of charge (PZC), metal‐organic frameworks (MOFs), Fourier transform infrared (FTIR), X‐ray diffraction (XRD), scanning electron microscopy (SEM ...
Yating Yang, Yuhan Li, Zhaohui Li, Hang Wei, Yaqi Wen, Po‐Hsiang Chang, Christopher Rensing, Ahmed I. Osman, Baoyu Kong   +8 more
wiley   +1 more source

Effect of Polyphenol-Rich Diet Combined with Leucine, Vitamin D3, and Magnesium Supplementation on Self-Reported Mobility and Health Perception in Adults at Risk of Sarcopenia: A 3-Months Quasi-Experimental Study

Life
Background: Sarcopenia is characterized by progressive muscle weakness, impaired physical function, and reduced quality of life. Multimodal strategies combining rehabilitation and nutritional support that influence gut microbiota may help improve ...
Diana-Lidia Tache-Codreanu, Ana-Maria Tache-Codreanu, Georgeta Stefan, Magdalena Rodica Trăistaru, Elena Rusu, Andrei Tache-Codreanu, Corina Sporea   +6 more
doaj   +1 more source

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source

Detection of Protein–Protein Interactions in Escherichia coli With Single Molecule Sensitivity

Advanced Science, EarlyView.
This article describes a regulatory circuit in Escherichia coli able to detect protein–protein interactions with exquisite sensitivity. The interaction between two hybrid proteins fused to Bordetella pertussis adenylate cyclase and its activator calmodulin triggers a potent cyclic AMP signaling cascade.
Marilyne Davi, Daniel Ladant
wiley   +1 more source

Sulfakinin Signaling Sense Circulating Fructose and Suppresses Food Consumption via Insulin‐Like Peptide in Bactrocera Dorsalis

Advanced Science, EarlyView.
This study discovered a new pathway that tells fruit flies when to stop eating. It found that rising blood sugar (fructose) is detected by a sensor called GR43a. This triggers a chain reaction involving the satiety signal sulfakinin and its receptor, ultimately activating a final satiety signal, ILP5.
Hong‐Fei Li, Bao Dong, Zheng‐Lin Ren, Xue‐Guang Zhu, Quan Lei, Yoonseong Park, Jin‐Jun Wang, Hong‐Bo Jiang   +7 more
wiley   +1 more source

Diabetes risk and amino acid profiles: cross-sectional and prospective analyses of ethnicity, amino acids and diabetes in a South Asian and European cohort from the SABRE (Southall And Brent REvisited) Study. [PDF]

, 2015
Aims/hypothesis: South Asian individuals have an increased risk of diabetes compared with Europeans that is unexplained by obesity and traditional or established metabolic measures.
Ala-Korpela, M, Chaturvedi, N, Eastwood, SV, Forouhi, NG, Godsland, IF, Hughes, AD, McKeigue, PM, Sattar, N, Tillin, T, Wang, Q, Würtz, P   +10 more
core  

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

Function of the Signal Peptide and N- and C-terminal Propeptides in the Leucine Aminopeptidase from \u3cem\u3eAeromonas proteolytica\u3c/em\u3e [PDF]

, 2004
The leucine aminopeptidase from Aeromonas proteolytica (also known as Vibrio proteolyticus) (AAP) is a metalloenzyme with broad substrate specificity. The open reading frame (ORF) for AAP encodes a 54 kDa enzyme, however, the extracellular enzyme has a ...
Bzymek, Krzysztof P., Campbell, Heidi, Chen, Guanjing, D\u27Souza, Ventris M., Holz, Richard C., Mitchell, Alice   +5 more
core   +1 more source