Results 151 to 160 of about 355,417 (306)

Light‐Activated Ruthenium Nanoclusters Reprogram the Metabolic‐Quorum Sensing Axis for Precision Periodontitis Therapy

Advanced Science, EarlyView.
Under 660 nm visible light, Ru NCs efficiently photocatalyze nitrate‐to‐ammonium conversion and modulate oral nitrogen metabolism. They precisely perturb Veillonella parvula, block its key support to Porphyromonas gingivalis, and exert an “inhibiting without killing” antivirulence effect.
Jing Zhou, Xiaolin Sun, Chengyu Liu, Yujia Shi, Meiqi Li, Meng Bo, Jingjie Zhai, Chunyan Li, Zhennan Wu, Xue Bai, Lin Wang   +10 more
wiley   +1 more source

Sex‐Based Body Composition Changes in Patients With Rectal Cancer Undergoing Preoperative Chemoradiotherapy: A Prospective Observational Study

Annals of Gastroenterological Surgery, EarlyView.
This prospective study observed that preoperative chemoradiotherapy for rectal cancer was associated with reductions in body fat and grip strength, which appeared to be more pronounced in female patients. These findings suggest that sex‐sensitive nutritional and exercise support may be beneficial to help maintain muscle mass and physical function ...
Shinya Abe, Hiroaki Nozawa, Kentaro Abe, Yumi Yokota, Shunsuke Hori, Yusuke Taguchi, Mitsutaka Yakabe, Kazuhito Sasaki, Sumito Ogawa, Soichiro Ishihara   +9 more
wiley   +1 more source

RagC and Map4K3 deficiency in high-grade gliomas drives proliferation and modulates mTORC1-dependent cellular functions. [PDF]

J Neuropathol Exp Neurol
Kahr J, Diaz-Peregrino R, Sandalcioglu IE, John P, Mawrin C.   +4 more
europepmc   +1 more source

Expanded Phenotype Associated With an Intronic PPP1R12A Variant: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Autosomal dominant PPP1R12A‐related genitourinary and/or brain malformation syndrome is a recently described multisystem disorder caused by loss‐of‐function variants in the protein phosphatase 1 regulatory subunit 12a (PPP1R12A) gene. To date, 22 affected individuals have been reported with variable brain malformations and genitourinary ...
Emily M. Bland, Amber Nakar Weinstein, Eric C. Kao, Xiaonan Zhao, Monika Weisz‐Hubshman   +4 more
wiley   +1 more source

Treatment strategies, radiological recovery, and neurodevelopmental outcomes in paediatric Maple Syrup Urine Disease: a 20-year single-centre experience from Türkiye. [PDF]

Metab Brain Dis
Uylaş K, Yazıcı H, Altınok YA, Çelik MY, Karapınar FE, Özkaya PY, Isik E, Eraslan C, Canda E, Cogulu O, Karapınar B, Habif S, Çoker M, Uçar SK.   +13 more
europepmc   +1 more source

Leucine-Sensitive Hypoglycæmia [PDF]

Proceedings of the Royal Society of Medicine, 1970
G, Tevaarwerk, C, Lowy, M, Hartog, T R, Fraser   +3 more
openaire   +2 more sources

Impact of leucine-rich diet on placenta's proteomic and metabolomic profiles of pregnant tumor-bearing rats. [PDF]

Cancer Biol Ther
Dos Santos IF, Salgado CM, Carregari VC, Dos Santos RW, de Souza DM, Viana LR, Gomes-Marcondes MCC.   +6 more
europepmc   +1 more source

Spectrum of Congenital Anomalies in Myhre Syndrome—Insights Into Effects Brought by Altered TGF‐β Signaling via Gain‐of‐Function Variants in SMAD4

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome is a rare genetic disorder characterized by progressive multisystem involvement. Gain‐of‐function missense heterozygous variants affecting the Ile500 residue and Arg496 residue of the SMAD4 gene are implicated in this condition.
Kawmadi Gunawardena, Alessandro De Falco, Deborah Osio, Eleanor Sherlock, Emma Kivuva, Erina Sasaki, Francis H. Sansbury, Nayana Lahiri, Patricia Foley, Sahar Mansour, Shane McKee, Tazeen Ashraf, Nicola Brunetti‐Pierri, Usha Kini   +13 more
wiley   +1 more source

The olfactory receptor SNIF-1 mediates foraging for leucine-enriched diets in <i>C. elegans</i>. [PDF]

Elife
Siddiqui R, Mehta N, Ranjith G, Félix MA, Chen C, Singh V.   +5 more
europepmc   +1 more source

Early diabetes‐like phenotypes in germ‐free mice induced by gut microbiota from patients with type 2 diabetes

Animal Models and Experimental Medicine, EarlyView.
Gut microbiota from patients with type 2 diabetes induced early diabetes‐like phenotypes in germ‐free mice, including progressive glucose intolerance and mild renal injury. Longitudinal profiling revealed persistent dysbiosis preceding stable metabolic dysfunction, with coordinated fecal and plasma metabolite alterations and a prominent L‐Dopa ...
Jianghao Feng, Xing Liu, Hua Zhu, Yun Yang, Wei Liu, Xiaoliang Jiang, Zhiwei Yang   +6 more
wiley   +1 more source