Results 171 to 180 of about 355,417 (306)

Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells

, 2014
Susumu Nakata,1 Emma Phillips,2 Violaine Goidts21Division of Oncological Pathology, Aichi Cancer Center Research Institute, Nagoya, Japan; 2Division of Molecular Genetics, German Cancer Research Center, Heidelberg, GermanyAbstract: The concept of cancer ...
Nakata S, Goidts V, Phillips E
core  

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Early laboratory indicators of acute metabolic decompensation during emergency presentations in pediatric maple syrup urine disease. [PDF]

Eur J Pediatr
Oral-Cebeci S, Aktuğlu-Zeybek Ç, Aslan B, Uysal ÖY, Cansever MŞ, Kıykım E, Zubarioglu T.   +6 more
europepmc   +1 more source

Human Leukocyte Elastase Triggered Nanoparticles for Targeted Antimicrobial Delivery and Oral Microbial Modulation

Advanced NanoBiomed Research, EarlyView.
This study explores enzyme‐responsive nanoparticles for targeted antimicrobial release in inflamed oral environments. Nanoparticles formed by complexing peptides and chlorhexidine respond to human leukocyte elastase and release chlorhexidine selectively. P7 (ECAAPVCE)‐based formulations show optimal properties and stability, with antimicrobial activity
Mohammed A. Hadis, Ignacio Insua, Farah N. S. Raja, Álvaro Vila, William M. Palin, Michael R. Milward, Paul R. Cooper, Sarah A. Kuehne, Owen Addison, Paco Fernandez‐Trillo   +9 more
wiley   +1 more source

Targeting muscle-vasculature crosstalk in aging through the integrative roles of L-citrulline, leucine, and exercise: focus on muscle metabolism, vascular function, and sarcopenia prevention. [PDF]

Front Nutr
Lin X, Zhang Y, Pu J, Peng Y.
europepmc   +1 more source

THE SPECIFICITY OF LEUCINE AMINOPEPTIDASE

Journal of Biological Chemistry, 1948
E L, SMITH, N B, SLONIM
openaire   +2 more sources

Intensive Induction in AML in the Era of Venetoclax: A Standing Count for “7 + 3”?

American Journal of Hematology, EarlyView.
Sudhir Tauro, Ayalew Tefferi
wiley   +1 more source

A transfer RNA inosine modification drives genome-wide synonymous recoding across human commensal bacterial families. [PDF]

PNAS Nexus
Katanski CD, Pathirage C, Chang JC, Veseli I, Smith TJ, Foo M, Wu Y, Hou Y, Tran HAV, Rudzka D, Zhang W, Bayat Tork MA, Lolans K, Willis AD, Tang W, Eren AM, Federle MJ, Koutmou KS, Pan T.   +18 more
europepmc   +1 more source

Leucin [PDF]

, 2017
openaire   +2 more sources

Insulin preserves fast-twitch muscle mass during early STZ-induced diabetes in rats. [PDF]

Biochem Biophys Rep
Yamasaki Y, Nomura K, Matsumoto Y, Fukuda-Takeji K, Miyatake Y, Suemasa N, Izumi-Mishima Y, Yasui-Yamada S, Kuroda M, Harada N, Tsutsumi YM, Kitamura T, Tsutsumi R, Nakaya Y, Sakaue H.   +14 more
europepmc   +1 more source