Results 91 to 100 of about 184,092 (245)

“Smelltronics”—From Gas to Smell Sensing

open access: yesAdvanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono   +7 more
wiley   +1 more source

Pharmacological aspects of the treatment of leukaemia in childhood

open access: yes, 2022
Leukaemia is the most common malignancy in childhood, with ALL being the most common subtype. However, in its entirety, leukaemia is a rare disease in childhood.
D'mello, Aarshia Vazirani
core  

Characterisation of T cell defects in acute myeloid leukaemia [PDF]

open access: yes, 2009
PhDUnderstanding the immune system in patients with cancer and how it interacts with malignant cells is critical for the development of successful immunotherapeutic strategies at a time when novel cancer treatment approaches are required.
Le Dieu, Helen Rifca
core   +2 more sources

DNA methylation-associated dysregulation of transfer RNA expression in human cancer

open access: yesMolecular Cancer, 2022
Margalida Rosselló-Tortella   +4 more
doaj   +1 more source

Enhancer RNAs contribute to genome reprogramming driven by a GATA3 noncoding variant in leukaemia

open access: yesScientific Reports
The GATA3 noncoding variant rs3824662 has been implicated in the pathogenesis of Ph-like B-ALL, where it is associated with extensive chromatin reorganisation, resulting in the dysregulation of multiple genes, including CRLF2 overexpression.
Thayana da Conceição Barbosa   +7 more
doaj   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

open access: yesAdvanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma   +15 more
wiley   +1 more source

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

open access: yesAdvanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang   +8 more
wiley   +1 more source

Machine Learning for Green Solvents: Assessment, Selection and Substitution

open access: yesAdvanced Science, EarlyView.
Environmental regulations have intensified demand for green solvents, but discovery is limited by Solvent Selection Guides (SSGs) that quantify solvent sustainability. Training a machine learning model on GlaxoSmithKline SSG, a database of sustainability metrics for 10,189 solvents, GreenSolventDB is developed. Integrated with Hansen solubility metrics,
Rohan Datta   +4 more
wiley   +1 more source

PB1705: THE HISTONE MODIFIER SETD6 IS EPIGENETICALLY REGULATED IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND INTERFERES WITH PROLIFERATION AND GENE EXPRESSION

open access: yesHemaSphere, 2023
Yoana Veselinova   +5 more
doaj   +1 more source

Mitochondria and Neuromast Tagging With Fluorescent Gallium‐Triapine Analogues: In Cellulo MP FLIM and Zebrafish Live Imaging

open access: yesAdvanced Science, EarlyView.
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green   +15 more
wiley   +1 more source

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