Results 81 to 90 of about 184,092 (245)

Sources of Human Hematopoietic Stem Cells for Transplantation–A Review

Cell Transplantation, 1995
Transplantation of hematopoietic stem cells provides a means of replacing a defective hematopoietic system in patients with a wide range of malignant and nonmalignant disorders that affect the blood forming tissue.
T.A.S. Amos, M.Y. Gordon
doaj   +1 more source

Incidence, Risk Factors and Management of Adverse Events in Contemporary Real‐World Care of Children with Juvenile Idiopathic Arthritis

Arthritis Care &Research, Accepted Article.
Objective We describe the frequency, risk factors, severity, and management of actionable and serious adverse events (AAE and SAE) in children with newly diagnosed Juvenile Idiopathic Arthritis (JIA) in Canada. Methods We enrolled patients within 3 months of JIA diagnosis in the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry,
Bashayer Alnuaimi, Roberta A. Berard, Jean‐Philippe Proulx‐Gauthier, Heinrike Schmeling, Michelle Batthish, Gilles Boire, Adam M. Huber, Dax G. Rumsey, Jaime Guzman, Gaëlle Chédeville, The CAPRI registry Investigators   +10 more
wiley   +1 more source

Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukaemia [PDF]

, 2018
Histone methyltransferases (HMTs) are important epigenetic regulators of gene transcription and are disrupted at the genomic level in a spectrum of human tumours including haematological malignancies. Using high-resolution single nucleotide polymorphism (
Oakes, C. C., Stamatopoulos, Kostas, Dyer, M., Larráyoz, María José, Rose-Zerilli, M. J. J., Knight, S., Ramos, S., Strefford, Jonathan C., Chelala, C., Rosenquist, Richard, Wang, J., Schuh, A., Ntoufa, S., Alsolami, R., Parker, Antón, Oscier, David G., Roghanian, A., McNicholl, F., Edelmann, J., Gibson, J., Tausch, E., Davis, Zadie, Brown, L., Blakemore, S., Pettitt, A., Ljungström, V., Parker, Helen, Stilgenbauer, S., Steele, A. J., Robbe, P., Packham, G., Hillmen, P., Clifford, R., Rodríguez-Vicente, Ana Eugenia, Chaplin, T., Wojdacz, T. K., Forconi, F., Cragg, M. S.   +37 more
core   +1 more source

Survival Outcomes in Older Adults with Axial Spondyloarthritis and Concomitant Cancer

Arthritis Care &Research, Accepted Article.
Objective The objective of this study was to determine survival outcomes in older adults with axial spondyloarthritis (axSpA) and concomitant cancer. Methods We conducted a population‐based study using Medicare claims data linked to Surveillance, Epidemiology, and End Results data to determine overall survival (OS) and cancer‐specific survival (CSS) in
Savannah Bowman, Mei Li, Xiudong Lei, Hui Zhao, Juan I. Ruiz, Sharon H. Giordano, Alexis R. Ogdie, Maria E. Suarez‐Almazor   +7 more
wiley   +1 more source

Vitamin K and childhood cancer: a report from the United Kingdom Childhood Cancer Study [PDF]

, 2003
The relationship between neonatal vitamin K received by the intramuscular (i.m.) route and the development of leukaemia or other cancers was investigated as part of a national case–control study of childhood cancer, using data abstracted from obstetric ...
Eden, O.B., Fear, NT, Day, N, Birch, Jillian, Fear, N. T., Simpson, J., Ansell, P, Fear, N.T., Simpson, J, Eden, O. B., E Roman, Roman, E., Roman, E, Ansell, P., N T Fear, N Day, O B Eden, ?, ?, Eden, OB, United Kingdom Childhood Cancer Study, Fear, N T, J Simpson, Eden, O B, Day, N., P Ansell   +24 more
core   +1 more source

P341: L-ASPARAGINASE BY-PRODUCT GLUTAMATE IMPEDES THE EFFECT OF CHEMOTHERAPY BY AUGMENTING GLUTATHIONE BIOSYNTHESIS

HemaSphere, 2023
Katerina Hlozkova, Maryna Vasylkivska, Martina Zwyrtkova, Matus Kolarik, Eliska Potuckova, Natividad Alquezar Artieda, Marketa Zaliova, Jan Trka, Daniel Tennant, Julia Starkova   +9 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Living with chronic lymphocytic leukaemia: patient perspectives from a global online cross-sectional survey on care pathways and impacts on quality of life

Frontiers in Hematology
BackgroundChronic Lymphocytic Leukaemia (CLL) is a slow-progressing condition often managed through active monitoring (“watch and wait”) strategies, which can lead to uncertainty for patients about prognosis, symptom management, and immunity-related ...
Kathryn Huntley, Alan J. Poots, Sarah Gunn, Jan Rynne, Jan Rynne, Nick York, Sam Salek   +6 more
doaj   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

P858: EPIGENETIC REGULATION OF CD155 ON MULTIPLE MYELOMA CELLS INFLUENCES ANTI-TUMOR T-CELL CYTOTOXICITY

HemaSphere, 2022
L. Martinez-Verbo, P. Llinàs-Arias, L. Villanueva, C. A. García-Prieto, D. Piñeyro, G. Ferrer, M. Esteller   +6 more
doaj   +1 more source