Results 121 to 130 of about 115,048 (305)

Recurrent Genomic Alterations in BCRi‐Experienced CLL Patients Treated With Venetoclax: Extended Phase 2 Follow‐Up

American Journal of Hematology, EarlyView.
Jennifer A. Woyach, Relja Popovic, Emily L. Rossi, Sanjana Singh, Toshihiko Oki, Tanya S. Rosenberg, Chen Qian, Michael Moran, Zihuan Liu, Michelle Boyer, Jeffrey Jones, Richard R. Furman, William Wierda, Jason Gotlib, Stephen J. Schuster, Brenda Chyla, Matthew S. Davids   +16 more
wiley   +1 more source

Cold atmospheric plasma‐mediated tumor microenvironment remodeling for cancer treatment

BMEMat, EarlyView.
Schematic presentation of CAP‐mediated TME remodeling. This review summarizes recent efforts in cold atmospheric plasma (CAP) application in cancer treatment, highlighting the anticancer potential of CAP, molecular mechanisms, and future perspectives for further improvement and clinical translation.
Israr Khan, Qiujie Fang, Cao Fei, Ziyuan Wang, Zhaowei Chen, Guojun Chen, Zhiming Xu, Shu Xu, Zhitong Chen   +8 more
wiley   +1 more source

Diagnosis and treatment of chronic lymphocytic leukemia: 2025 recommendations of the Brazilian Group of Chronic Lymphocytic Leukemia of the Brazilian Association of Hematology and Hemotherapy (ABHH)

Hematology, Transfusion and Cell Therapy
Chronic lymphocytic leukemia, characterized by an accumulation of monoclonal B lymphocytes, is the most common adult leukemia. The disease predominantly affects older adults, with a significant proportion being asymptomatic at diagnosis.
Carlos Sérgio Chiattone, Fernanda de Morais Marques, Valeria Buccheri, Mihoko Yamamoto, Sergio Costa Fortier, Maura Rosane Valerio Ikoma-Colturato, Nelson Hamerschlak, Vera Lucia de Piratininga Figueiredo, Talita Maira Bueno da Silveira, Abel Costa, Dani Laks, Rony Schaffel, Wolney Gois Barreto, Adriana Scheliga, Pedro Amoedo Fernandes, Samir Kanaan Nabhan, Rafael Dezen Gaiolla, Matheus Vescovi Gonçalves, Danielle Leão Cordeiro de Farias, Glaciano Ribeiro, Marcelo Pitombeira de Lacerda, Celso Arrais-Rodrigues   +21 more
doaj   +1 more source

Chronic Lymphocytic Leukemia — Microenvironment and B Cells

, 2015
Chronic lymphocytic leukemia (CLL) has been considered as an accumulative disease deriving from defects in apoptosis, but recent studies showed that CLL is a dynamic process in which monoclonal B cells proliferate within pseudofollicular proliferation centers.
Vladimirova, Rositsa, Popova, Dora, Vikentieva, Elena, Guenova, Margarita   +3 more
openaire   +3 more sources

Somatic Mutations in Acquired Pure Red Cell Aplasia: Incidence and Implications

American Journal of Hematology, EarlyView.
Robert T. Means Jr
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

BMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma, Songyan Li, Jie Yan, Xuechun Wang, Wen Zhao, Yunxuan Song, Dongdong Liu, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +9 more
wiley   +1 more source

Cytotoxic lymphocytes in B-cell chronic lymphocytic leukemia

Annals of Hematology, 1990
The occurrence of cytotoxic lymphocyte subpopulations (i.e., CD 16+, CD57+ and cytotoxic CD 8+) was studied in the peripheral blood of 18 B-cell chronic lymphocytic leukemia (B-CLL) patients. The absolute numbers of CD 57+, CD 16+ and cytotoxic CD 8+ lymphocytes were increased in the peripheral blood of untreated patients as compared with healthy ...
Terstappen, Leonardus Wendelinus Mathias Marie, de Grooth, B.G., Segers-Nolten, Gezina M.J., Greve, Jan   +3 more
openaire   +1 more source

Optimizing Cell Sorting Performance: A Comparative Study Utilizing Spectral Flow Cytometry

Cytometry Part A, EarlyView.
Strategy for the Evaluation of Multi‐way Sort Performance. ABSTRACT The introduction of full spectral technology in flow cytometry has facilitated access to an increasing number of markers to define cell subsets with higher precision. Cell sorting has a unique advantage to combine high throughput single cell analysis and recovery of rare live single ...
Jarina Pena DaMata, Randall Johnson, Iyadh Douagi   +2 more
wiley   +1 more source

Monocyte maturation pattern by flow cytometry expression of CD64, CD300e, and CD14 correlates to presence of myeloid neoplasm and helps identify blast equivalents in the setting of monocytic neoplasm

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract CD300e is a marker of mature monocytes in flow cytometry; however, there is limited detailed information on staining patterns in conjunction with other monocyte markers. We evaluated the flow cytometric staining patterns of CD64, CD14, and CD300e in 12 negative and 33 positive peripheral blood specimens and 16 negative and 56 positive bone ...
Jenny Zhang, Jacob Kaplan, Elizabeth Courville   +2 more
wiley   +1 more source

Flow cytometry‐based monitoring of chimeric antigen receptor (CAR) T cells: Reagent selection, assay design, and clinical utility

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley   +1 more source