Results 121 to 130 of about 17,826,638 (304)

Interferon Alfa in the treatment of B-cell chronic lymphocytic leukemia [PDF]

, 1994
Knauf, W. U., Maubach, P. A., Adolf, D., Mitrou, P. S., Emmerich, B., Ziegle-Heitbrock, H. W. L., Thiel, E., Langenmayer, Irmgard, Bergmann, L., Dietzfelbinger, H., Nerl, C.   +10 more
core   +1 more source

Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia

, 2018
The formation of B-cell receptor immunoglobulin (BcR IG) is the result of a multi-step process that starts at the pro-B cell stage with the VDJ gene recombination of IG genes of the heavy chain, followed by VJ recombination of the light chain genes at ...
Hadzidimitriou, Anastasia, Stamatopoulos, Kostas, Chrysoula Belessi, Ghia, P, Agathangelidis, Andreas, Rosenquist, R, Belessi, C, Agathangelidis, A, Stamatopoulos, K,, Paolo Ghia, Rosenquist, Richard, Hadzidimitriou, A, Richard Rosenquist, Davi, Frederic, Andreas Agathangelidis, Anastasia Hadzidimitriou, Kostas Stamatopoulos, Ghia, Paolo, Belessi, Chrysoula, Frederic Davi, Davi, F   +20 more
core   +1 more source

A practical difference from the normal approach to evaluate natural killer (NK) cells and NK cell neoplasms by flow cytometry

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Natural killer (NK) cell neoplasms span indolent to highly aggressive entities, and flow cytometric immunophenotyping is central to their detection and classification. However, distinguishing reactive from neoplastic NK cell expansions can be challenging because NK cells lack somatically recombined antigen receptors, and reactive states may ...
Aaron J. Wilk, Afshin Shameli, Erik Ames, Jonathan R. Fromm, Bartosz Grzywacz, Min Shi, Sindhu Cherian, Jean Oak   +7 more
wiley   +1 more source

Subset‐specific and tissue‐specific expression of NK‐cell markers and killer immunoglobulin‐like receptors: Implications for NK‐cell clonality assessment

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Accurate immunophenotypic evaluation of natural killer (NK)‐cell neoplasms is challenging because NK‐cells lack somatically rearranged antigen receptors, are comprised of phenotypically distinct subsets, and exhibit tissue‐specific subset distribution. We developed a flow cytometry (FC) panel for NK‐cell immunophenotypic analysis and clonality
Valerie Woodings, Orrin Koepke, Jason E. Love, Alireza Torabi, Lianqun Qiu, Jonathan R. Fromm, Sindhu Cherian, Afshin Shameli   +7 more
wiley   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Report of Public Meeting to Seek Input on Gaps in Chronic Lymphocytic Leukemia (CLL) Radiogenicity Research held July 21, 2004 [PDF]

"Chronic lymphocytic leukemia (CLL) is the most common adult leukemia in the Western world. While the etiology of CLL is largely unknown, it is currently the only cancer assigned a probability of causation by ionizing radiation of zero under the US ...

core   +1 more source

Diagnosis and treatment of chronic lymphocytic leukemia: recommendations from the Brazilian Group of Chronic Lymphocytic Leukemia

Revista Brasileira de Hematologia e Hemoterapia
Chronic lymphocytic leukemia is characterized by clonal proliferation and progressive accumulation of B-cell lymphocytes that typically express CD19+, CD5+ and CD23+.
Celso Arrais Rodrigues, Matheus Vescovi Gonçalves, Maura Rosane Valério Ikoma, Irene Lorand-Metze, André Domingues Pereira, Danielle Leão Cordeiro de Farias, Maria de Lourdes Lopes Ferrari Chauffaille, Rony Schaffel, Eduardo Flávio Oliveira Ribeiro, Talita Silveira da Rocha, Valeria Buccheri, Yuri Vasconcelos, Vera Lúcia de Piratininga Figueiredo, Carlos Sérgio Chiattone, Mihoko Yamamoto   +14 more
doaj   +1 more source

Selective targeting of NOTCH-1 for therapeutic purposes in xenograft models of T-acute lymphoblastic leukemia [PDF]

, 2013
T-cell acute lymphoblastic leukemia (T-ALL) is an heterogeneous disease, characterized by several genetic alterations and polymorphic clinical features both in children and adults.
Agnusdei, Valentina
core  

Involvement of Tis11b, an AU-rich binding protein, in induction of apoptosis by rituximab in B cell chronic lymphocytic leukemia cells [Letter to editor]

, 2009
B-cell chronic lymphocytic leukemia is the commonest form of leukemia in the Western world, characterized by an accumulation of monoclonal CD5+ B cells in the peripheral blood and lymphoid organs.
Carr, R., Wickremasinghe, R.G., Carr, R, Yong, K. L., Baou, M., Jewell, A, Jewell, A.P., Baou, M, Jewell, A., Marsh, P, Muthurania, A, Yong, K L, Murphy, J.J., Wickremasinghe, R G, Murphy, J. J., Yong, K.L., Murphy, J J, Marsh, P., Muthurania, A., Wickremasinghe, R. G.   +19 more
core   +1 more source

Risk of Developing Subsequent Primary Colorectal Cancers Among Non‐Colorectal Cancer Survivors: Implications for Prevention and Screening

International Journal of Cancer, EarlyView.
ABSTRACT Cancer survivors have an elevated risk of developing subsequent primary cancers, including colorectal cancer (CRC), and may benefit from tailored screening approaches to reduce incidence and morbidity. A retrospective cohort of adults diagnosed with cancer (excluding CRC) in Alberta, Canada from 2000 to 2021 who survived at least 6 months was ...
Dylan E. O'Sullivan, Robert J. Hilsden, Hannah Harsanyi, Matthew T. Warkentin, Kareem Jamani, Huiming Yang, Darren R. Brenner, Safiya Karim, Winson Y. Cheung, Yibing Ruan   +9 more
wiley   +1 more source