Results 271 to 280 of about 115,818 (290)

Richter syndrome in B‐cell chronic lymphocytic leukemia

Pathology International, 2003
Richter syndrome (RS) is well known as a secondary high‐grade lymphoma, mostly diffuse large B‐cell lymphoma (DLBCL) developed in patients with B‐cell chronic lymphocytic leukemia (B‐CLL). In this review, we describe clinicopathological, histological, immunophenotypical and genetic findings of RS.
Naoya, Nakamura, Masafumi, Abe
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Targeting B-cell anergy in chronic lymphocytic leukemia

Blood, 2013
Key Points A sizable fraction of CLL patients is characterized by the expansion of clonal B cells with anergic features. The constitutive biochemical signature of B-cell anergy can be efficiently targeted in CLL for therapeutic purposes.
Apollonio B, Scielzo C, Bertilaccio MT, Ten Hacken E, Scarfò L, Ranghetti P, Stevenson F, Packham G, GHIA , PAOLO PROSPERO, Muzio M, CALIGARIS CAPPIO , FEDERICO   +10 more
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11q13 Rearrangement in B Cell Chronic Lymphocytic Leukemia

Leukemia & Lymphoma, 1997
Translocation t(11;14)(q13;q32) and/or 11q13 rearrangements have been reported in various B cell immunoproliferative disorders. They appear to be frequent in mantle cell zone lymphoma (MZL) and rare in B-cell chronic lymphocytic leukemia (B-CLL). Discrimination between MZL and B-CLL is sometimes uncertain on the basis of morphology and immunophenotype.
F, Brizard, B, Dreyfus, F, Guilhot, J, Tanzer, A, Brizard   +4 more
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T-lymphocyte function in B-cell chronic lymphocytic leukemia

Clinical Immunology and Immunopathology, 1980
Summary. B‐enriched lymphocyte populations from patients with chronic lymphocytic leukaemia (CLL) were compared to B‐enriched lymphocyte populations from normal age‐matched controls for their ability to stimulate a proliferative response and to generate cytotoxic cells in allogeneic mixed lymphocyte cultures (MLC).
J A, Wolos, F R, Davey
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Antigen Receptor Function in Chronic Lymphocytic Leukemia B Cells

Leukemia & Lymphoma, 1996
Functional studies revealed that two groups of B chronic lymphocytic leukemia (B-CLL) can be distinguished based on their capacity to mount a proliferative response following B-cell antigen receptor (BCR) cross-linking. The molecular basis for the functional distinction between these B-CLL groups most probably resides within or proximal to the BCR ...
Lankester, A. C., Schijndel, G. M., Pakker, N. G., van Oers, R. H., van Lier, R. A.   +4 more
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E Rosette Formation in B Cell Chronic Lymphocytic Leukemia

Acta Haematologica, 1992
We describe a patient with B cell chronic lymphocytic leukemia whose B lymphocytes showed the capacity to form rosettes with sheep red blood cells during prolymphocytoid transformation of the disease. In this case, rosette formation was found to be related to the presence of the classic E rosette receptor since the leukemic cells were recognized by the
MUSOLINO, Caterina, DI CESARE, Enrico, ALONCI, Andrea, ALLEGRA, Alessandro, Orlando A, Grosso P, Buda G, SQUADRITO, Giuseppe   +7 more
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ATM mutations in B-cell chronic lymphocytic leukemia.

Cancer research, 1999
Mutations in the ATM gene located on the long arm of chromosome 11 at 11q22-23 cause ataxia-telangiectasia, an autosomal recessive disorder that is associated with increased incidence of malignancy and, particularly, lymphoid tumors. A role for ATM in the development of sporadic T-cell chronic leukemias is supported by the finding of loss of ...
F. Bullrich, RASIO, DEBORA, S. Kitada, P. Starostik, T. Kipps, M. Keating, M. Albitar, J. C. Reed, Croce, C. M. Cancer Res Jan   +9 more
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[CD43 in B-cell chronic lymphocytic leukemia].

Polskie Archiwum Medycyny Wewnetrznej, 2000
CD43 (other names: sialophorin, leukosialin, sialoglycoprotein of white blood cells) is an integral cell membrane mucin. In population of peripheral B cells CD43 occurs only on activated B cells and CD5 positive B cells. These last cells create neoplasm population in patients with B-cell chronic lymphocytic leukemia (B-CLL).
J, Roliński, Z M, Rupniewska, A, Dmoszyńska, E, Wasik-Szczepanek, A, Bojarska-Junak   +4 more
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B Cell Chronic Lymphocytic Leukemia

Annals of the New York Academy of Sciences, 2003
RAJENDRA N. DAMLE, FABIO GHIOTTO, ANGELO VALETTO, EMILIA ALBESIANO, STEVEN L. ALLEN, PHILIP SCHULMAN, VINCENT P. VINCIGUERRA, KANTI R. RAI, MANLIO FERRARINI, NICHOLAS CHIORAZZI   +9 more
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Genetics of B-Cell Chronic Lymphocytic Leukemia

2004
B-cell chronic lymphocytic leukemia (B-CLL) is the most frequent type of leukemia among adults in the Western world, with an incidence of about 5 cases per 100,000 residents annually (1,2). The disease affects mainly people of advanced age, but about 20% of patients are younger than 55 (3).B-CLL is characterized by the accumulation of lymphocytes that ...
Stephan Stilgenbauer, Peter Lichter, Hartmut Döhner   +2 more
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