Results 171 to 180 of about 76,259 (245)

Tumour Cell Size Control and Its Impact on Tumour Cell Function

open access: yesCell Proliferation, EarlyView.
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley   +1 more source

Lymphoid stroma in all its states. [PDF]

open access: yesFront Immunol
Barbier N, Isen V, Tarte K, Roulois D.
europepmc   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

open access: yesThe FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi   +16 more
wiley   +1 more source

Unveiling the Molecular Landscape of MPO in Kikuchi's Disease: Protein Expression, mRNA Levels, and Genetic Polymorphisms

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
This study investigates myeloperoxidase (MPO) in Kikuchi's disease, analyzing protein expression and mRNA levels in 43 patients. Results reveal 100% MPO protein positivity, elevated mRNA expression, and a positive correlation between mRNA and protein levels.
Chen Chang   +4 more
wiley   +1 more source

Significance of Myelodysplasia‐Related Mutations and the Genetic Landscape of Acute Leukemias of Ambiguous Lineage

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT The recent fifth edition WHO classification and ICC classification systems have moved further toward genetically defined classifications of acute leukemias. Both now recognize myelodysplasia‐related (MR) mutations as defining of MDS‐related AML (AML‐MR).
Timothy J. Kirtek, Olga K. Weinberg
wiley   +1 more source

Modulation of Tumor Metabolism in Acute Leukemia by Plant-Derived Polymolecular Drugs and Their Effects on Mitochondrial Function. [PDF]

open access: yesMolecules
Arévalo C   +7 more
europepmc   +1 more source

Characterization of ex vivo expanded natural killer cells for cancer immunotherapy

open access: yesImmunology &Cell Biology, EarlyView.
In this study, we characterized the phenotype and function of ex vivo expanded TS‐natural killer (NK) cells over a 13‐day culture period. We show dynamic cytokine secretion profiles and enhanced cytotoxicity upon coculture with tumor targets, supporting their utility in cancer immunotherapy.
Jin Young Min   +5 more
wiley   +1 more source

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