Results 171 to 180 of about 689,537 (284)

Comparison of severe aplastic anaemia and lower risk hypoplastic myelodysplastic neoplasms: Critical role of megakaryocyte count in distinguishing aplastic anaemia from myelodysplastic neoplasms

British Journal of Haematology, EarlyView.
In our central morphological review system, megakaryocyte counts are prioritized alongside BM cellularity to differentiate between AA and MDS. A retrospective analysis of patients with SAA and those with LR‐hMDS, registered in that system, revealed a significant difference in outcomes.
Tomoya Maeda, Akira Matsuda, Junya Kanda, Hiroshi Kawabata, Takayuki Ishikawa, Kaoru Tohyama, Akira Kitanaka, Kayano Araseki, Kei Shimbo, Tomoko Hata, Takahiro Suzuki, Hidekazu Kayano, Kensuke Usuki, Maki Shindo‐Ueda, Nobuyoshi Arima, Masaharu Nohgawa, Akiko Ohta, Shigeru Chiba, Yasushi Miyazaki, Shinji Nakao, Keiya Ozawa, Shunya Arai, Mineo Kurokawa, Akifumi Takaori‐Kondo, Kinuko Mitani, the Japanese National Research Group on Idiopathic Bone Marrow Failure Syndromes   +25 more
wiley   +1 more source

How we manage immune‐mediated thrombotic thrombocytopenic purpura after rituximab failure or intolerance

British Journal of Haematology, EarlyView.
The use of rituximab as a pre‐emptive treatment in immune‐mediated thrombotic thrombocytopenic purpura (iTTP) is the current standard of care. However, for patients refractory to rituximab or for those with contraindication, further treatment guidelines are scarce.
Julia Weisinger, Jehane Fadlallah, Bérangère Joly, Agnès Veyradier, Paul Coppo   +4 more
wiley   +1 more source

Inmunofenotipaje celular en el diagnostico de la leucemia mieloide aguda Cellular immunophenotyping in the diagnosis of acute myeloid leukemia

Revista Cubana de Hematología, Inmunología y Hemoterapia, 2005
The immunophenotype of the leukemic cells was analyzed in 72 patients with diagnosis of acute myeloid leukemia (AML) that received attention at the Institute of Hematology and Immunology during 13 years. The cellular immunophenotyping (CIP) was performed
doaj  

Coexistence of Acute Myeloid Leukemia and B-cell Non-Hodgkin Lymphoma Diagnosed on a Bone Marrow Trephine Biopsy. [PDF]

Cureus
Ahmad N, Asif H, Burhan M, Ahmad AH, Tariq Mahmood M.   +4 more
europepmc   +1 more source

Atezolizumab, obinutuzumab and venetoclax for the treatment of patients with relapsed/refractory B non‐Hodgkin lymphoma: Final analysis of a phase II trial from the LYSA group

British Journal of Haematology, EarlyView.
Summary Developing new therapeutic regimens for relapsed/refractory (R/R) B non‐Hodgkin lymphoma (NHL) patients remains a significant unmet clinical need. Our objective was to evaluate atezolizumab (ATE), obinutuzumab (OBI) and venetoclax (VEN) combination in patients with R/R NHL who had received at least one prior anti‐CD20‐containing ...
Charles Herbaux, Emmanuel Bachy, Reda Bouabdallah, Stéphanie Guidez, Olivier Casasnovas, Pierre Feugier, Gandhi Damaj, Hervé Tilly, Loïc Ysebaert, Steven Le Gouill, Nadine Morineau, Emmanuel Gyan, Rémy Gressin, Roch Houot, Morgane Cheminant, Franck Morschhauser, Catherine Thieblemont, Corinne Haioun, Emmanuelle Nicolas‐Virelizier, Luc‐Matthieu Fornecker, Nicolas Daguindau, Guillaume Cartron   +21 more
wiley   +1 more source

Advancing Leukemia Management Through Liquid Biopsy: Insights into Biomarkers and Clinical Utility. [PDF]

Cancers (Basel)
Hollanda CN, Gualberto ACM, Motoyama AB, Pittella-Silva F.   +3 more
europepmc   +1 more source

PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

Nature Genetics, 2019
Zhaohui Gu, M. Churchman, K. Roberts, Ian Moore, Xin Zhou, J. Nakitandwe, Kohei Hagiwara, S. Pelletier, S. Gingras, H. Berns, D. Payne-Turner, Ashley D. Hill, I. Iacobucci, Lei Shi, S. Pounds, Cheng Cheng, Deqing Pei, Chunxu Qu, S. Newman, M. Devidas, Yunfeng Dai, S. Reshmi, J. Gastier-Foster, E. Raetz, M. Borowitz, B. Wood, W. Carroll, P. Zweidler-McKay, K. Rabin, L. Mattano, K. Maloney, A. Rambaldi, O. Spinelli, J. Radich, M. Minden, J. Rowe, S. Luger, M. Litzow, M. Tallman, J. Racevskis, Yanming Zhang, R. Bhatia, J. Kohlschmidt, K. Mrózek, C. Bloomfield, W. Stock, S. Kornblau, H. Kantarjian, M. Konopleva, W. Evans, S. Jeha, C. Pui, Jun J. Yang, E. Paietta, J. Downing, M. Relling, Jinghui Zhang, M. Loh, S. Hunger, C. Mullighan   +59 more
semanticscholar   +1 more source

Patients With Atopic Dermatitis Show Increased Clonal Hematopoiesis and Risk of Hematological Cancer

Allergy, EarlyView.
Verena Vogi, Emina Jukic, Robert Gruber, Andre Fiona, Deborah Minzaghi, Johannes Zschocke, Sandrine Dubrac   +6 more
wiley   +1 more source

Genomic variant profiling in blast‐phase paediatric chronic myeloid leukaemia: Predisposing and driving alterations

British Journal of Haematology, EarlyView.
To identify pathogenic somatic and germline gene variants associated with blast‐phase transformation and cancer predisposition in paediatric chronic myeloid leukaemia (CML), n = 19 patients with blast‐phase paediatric CML were analysed with whole genome and targeted panel sequencing and compared to n = 19 patients with chronic phase paediatric CML.
Yvonne Lisa Behrens, Thea Reinkens, Winfried Hofmann, Amelie Gumann, Alisa Förster, Laura Gaschler, Tabita Ghete, Renate Strasser, Jennifer Espenkötter, Bernd Haermeyer, Michaela Losch, Stephanie Sembill, Zofia Wotschofsky, Stephan von Hörsten, Wolfgang Schuh, Nataliya Di Donato, Meinolf Suttorp, Manuela Krumbholz, Tim Ripperger, Brigitte Schlegelberger, Gudrun Göhring, Markus Metzler, Axel Karow   +22 more
wiley   +1 more source

Modulation of Tumor Metabolism in Acute Leukemia by Plant-Derived Polymolecular Drugs and Their Effects on Mitochondrial Function. [PDF]

Molecules
Arévalo C, Carlosama C, Rojas L, Cala MP, Hamon MP, Friguet B, Barreto A, Fiorentino S.   +7 more
europepmc   +1 more source