Results 181 to 190 of about 689,537 (284)

HCVAD plus imatinib or dasatinib in lymphoid blastic phase chronic myeloid leukemia

Cancer, 2014
P. Strati, H. Kantarjian, D. Thomas, S. O'brien, S. Konoplev, J. Jorgensen, R. Luthra, L. Abruzzo, E. Jabbour, A. Quintás-Cardama, G. Borthakur, S. Faderl, F. Ravandi, J. Cortes   +13 more
semanticscholar   +1 more source

Anaplastic large cell lymphoma in children and adolescents

British Journal of Haematology, EarlyView.
Summary Anaplastic lymphoma kinase (ALK)‐positive anaplastic large‐cell lymphoma (ALCL) accounts for >95% of ALCL cases in children and adolescents. The first description of ALCL as a CD30‐positive lymphoma in 1985 was followed by the detection of chromosomal translocations involving the ALK gene at chromosome 2p23.
Eric J. Lowe, Wilhelm Woessmann
wiley   +1 more source

Unusual Presentation of Childhood Leukemia With Vaginal Bleeding: A Case Report. [PDF]

Case Rep Hematol
Çalışkan Kamış Ş.
europepmc   +1 more source

Protein tyrosine phosphatases as emerging targets for cancer immunotherapy

British Journal of Pharmacology, EarlyView.
Abstract Contemporary strategies in cancer immunotherapy, despite remarkable success, remain constrained by inherent limitations such as suboptimal patient responses, the emergence of drug resistance, and the manifestation of pronounced adverse effects. Consequently, the need for alternative strategies for immunotherapy becomes clear.
Zihan Qu, Jiajun Dong, Zhong‐Yin Zhang
wiley   +1 more source

Diagnostic approach to leukemia cutis : A differential diagnostic step-by-step algorithm. [PDF]

Am J Clin Pathol
Jenei A, Tzankov A.
europepmc   +1 more source

Assessment of Spinster homologue 2 (Spns2)‐dependent transport of sphingosine‐1‐phosphate as a therapeutic target

British Journal of Pharmacology, Volume 182, Issue 9, Page 2014-2030, May 2025.
Abstract Background and Purpose Sphingosine‐1‐phosphate (S1P) receptor modulator (SRM) drugs suppress immune system function by disrupting lymphocyte trafficking, but SRMs are broadly immunosuppressive with on‐target liabilities. Another strategy to modulate the immune system is to block S1P transport.
Yugesh Kharel, Tao Huang, Kyle Dunnavant, Daniel Foster, George M. P. R. Souza, Katherine E. Nimchuk, Andrea R. Merchak, Caitlin M. Pavelec, Zuzanna J. Juskiewicz, Simon S. Alexander, Alban Gaultier, Stephen B. G. Abbott, Jung‐Bum Shin, Brant E. Isakson, Wehao Xu, Norbert Leitinger, Webster L. Santos, Kevin R. Lynch   +17 more
wiley   +1 more source

Global, regional, and national burden of leukemia, 1990-2021: a systematic analysis of the global burden of disease in 2021. [PDF]

Front Med (Lausanne)
Chen J, Pang W, Deng M, Zheng R, Chen Y, Zhang Z, Tan Z, Bai Z.   +7 more
europepmc   +1 more source

The Clinical and Molecular Characterization of Distinct Subtypes in Adult T Cell Acute Lymphoblastic Leukemia

Cancer Science, Volume 116, Issue 4, Page 1126-1138, April 2025.
This study categorized T‐ALL patients into 3 distinct subgroups: ETP‐like group, immature T‐ALL group, and mature T‐ALL group based on transcriptome. ETP‐like patients exhibited characteristics of early T‐cell development, which can be identified by the ETP‐like score model. ABSTRACT T‐cell acute lymphoblastic leukemia (T‐ALL) is a clonal proliferative
Heye Yu, Wenbing Liu, Junping Zhang, Leling Xie, Anli Lai, Zheng Tian, Kejing Tang, Haiyan Xing, Ying Wang, Hui Wei, Qing Rao, Runxia Gu, Min Wang, Huijun Wang, Jianxiang Wang, Shaowei Qiu   +15 more
wiley   +1 more source

A shadow in the treatment of acute leukemia: lineage switch. [PDF]

Blood Sci
Zhou Q, Wang Y.
europepmc   +1 more source

GD2 is a Crucial Ganglioside in the Signal Modulation and Application as a Target of Cancer Therapeutics

Cancer Science, Volume 116, Issue 4, Page 862-870, April 2025.
Among cancer‐associated antigens, ganglioside GD2 is the most crucial and essential carbohydrate antigen as a modulator of malignant signals and as a target of immunotherapy for refractory cancers. In particular, GD2 is now believed to be a marker of cancer stem cells and to be essentially involved in the features of cancer stemness.
Koichi Furukawa, Yuhsuke Ohmi, Kazunori Hamamura, Yuki Ohkawa, Noboru Hashimoto, Orie Tajima, Kei Kaneko, Keiko Furukawa   +7 more
wiley   +1 more source