Results 191 to 200 of about 713,469 (335)

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes.

Blood, 2009
J. Vardiman, J. Thiele, D. Arber, R. Brunning, M. Borowitz, A. Porwit, N. Harris, M. L. Le Beau, E. Hellström-Lindberg, A. Tefferi, C. Bloomfield   +10 more
semanticscholar   +1 more source

Dual Inhibition of Mast Cells and Thymic Stromal Lymphopoietin Using a Novel Bispecific Antibody, CDX‐622

Allergy, EarlyView.
SCF and TSLP expression are known to drive unique immune responses leading to the onset of allergic and inflammatory diseases. Here, we describe the characterization of a novel bsAb, CDX‐622, that targets SCF and TSLP. CDX‐622 inhibits MC functions through SCF starvation and Type 2 inflammatory responses via TSLP inhibition.
Michael B. Murphy, Laura Vitale, Thomas O'Neill, Deena M. Maurer, Linda Malenchek, Andrea Crocker, Colleen Patterson, Laura Mills‐Chen, Virginia Saley, Nicole M. Antczak, James M. Boyer, Kelly M. McManus, Noe Rico Montanari, Russell A. Hammond, Joel Goldstein, Lawrence J. Thomas, Tibor Keler, Diego Alvarado   +17 more
wiley   +1 more source

Composite chronic lymphocytic leukemia and mantle cell lymphoma involving the bone marrow: a case report and literature review. [PDF]

J Pathol Transl Med
Demianets R, O'Brien S, Mahdavi K, Niu C, Aslam S, Tran T, Zhang Y, Gamayo A, Zhao X, Rezk SA.   +9 more
europepmc   +1 more source

PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia

Nature Genetics, 2019
Zhaohui Gu, M. Churchman, K. Roberts, Ian Moore, Xin Zhou, J. Nakitandwe, Kohei Hagiwara, S. Pelletier, S. Gingras, H. Berns, D. Payne-Turner, Ashley D. Hill, I. Iacobucci, Lei Shi, S. Pounds, Cheng Cheng, Deqing Pei, Chunxu Qu, S. Newman, M. Devidas, Yunfeng Dai, S. Reshmi, J. Gastier-Foster, E. Raetz, M. Borowitz, B. Wood, W. Carroll, P. Zweidler-McKay, K. Rabin, L. Mattano, K. Maloney, A. Rambaldi, O. Spinelli, J. Radich, M. Minden, J. Rowe, S. Luger, M. Litzow, M. Tallman, J. Racevskis, Yanming Zhang, R. Bhatia, J. Kohlschmidt, K. Mrózek, C. Bloomfield, W. Stock, S. Kornblau, H. Kantarjian, M. Konopleva, W. Evans, S. Jeha, C. Pui, Jun J. Yang, E. Paietta, J. Downing, M. Relling, Jinghui Zhang, M. Loh, S. Hunger, C. Mullighan   +59 more
semanticscholar   +1 more source

Understanding the Variability of Peanut‐Oral Immunotherapy Responses by Multi‐Omics Profiling of Immune Cells

Allergy, EarlyView.
This study analyzes molecular drivers of OIT responsiveness. Multi‐omics profiling of peanut‐stimulated PBMCs in a controlled peanut‐OIT trial identifies immune, transcriptomic, and epigenetic changes distinguishing complete responders from incomplete responders. Key findings highlight gastrointestinal immune mechanisms, including extracellular exosome
Aleix Arnau‐Soler, Sarah E. Ashley, Ahla Ghauri, Alexander C. S. N. Jeanrenaud, Ingo Marenholz, Katharina Blumchen, Penelope Cibin, Alisa Iakupova, Norbert Hubner, Kirsten Beyer, Young‐Ae Lee   +10 more
wiley   +1 more source

Systemic CD3+ T-Cell Lymphoblastic Leukemia in a Bearded Dragon (<i>Pogona vitticeps)</i>: Clinical, Therapeutic, and Pathological Findings. [PDF]

Animals (Basel)
Miljković J, Jonker A, Đuričić D, Horvatek Tomić D, Belić M, Faraguna S, Pavić Vulinović M, Shek Vugrovečki A, Lukač M, Šoštarić-Zuckermann IC, Šmit I.   +10 more
europepmc   +1 more source

HCVAD plus imatinib or dasatinib in lymphoid blastic phase chronic myeloid leukemia

Cancer, 2014
P. Strati, H. Kantarjian, D. Thomas, S. O'brien, S. Konoplev, J. Jorgensen, R. Luthra, L. Abruzzo, E. Jabbour, A. Quintás-Cardama, G. Borthakur, S. Faderl, F. Ravandi, J. Cortes   +13 more
semanticscholar   +1 more source

Acute onset neurological deficits and hypocalcaemia associated with nutritional secondary hyperparathyroidism in three juvenile servals (Leptailurus serval)

Australian Veterinary Journal, EarlyView.
Nutritional secondary hyperparathyroidism is a metabolic disorder caused by an imbalance in calcium homeostasis and is typically associated with the feeding of a calcium‐deficient diet. Nutritional secondary hyperparathyroidism has been reported in domestic species, including cats and dogs, as well as captive carnivores and wildlife including lions ...
JL Austen, JW Wheelahan, J O'Dwyer, S Beths, NL Rourke, BR Gardner   +5 more
wiley   +1 more source

A critical review of management of allogeneic transplant‐eligible adults with Ph+ acute lymphoblastic leukaemia

British Journal of Haematology, EarlyView.
Proposed management of newly diagnosed Philadelphia chromosome‐positive (Ph+) acute lymphoblastic leukaemia (ALL) in transplant‐eligible patients. Suggested considerations when deciding the treatment pathway available to a newly diagnosed Ph+ ALL patient that would be deemed transplant eligible. Summary Acute lymphoblastic leukaemia (ALL) in 20%–30% of
Naranie Shanmuganathan, Andrew Grigg
wiley   +1 more source

Mucocutaneous Manifestations of Leukemias and Lymphomas: A Clinical Study from a Tertiary Care Center in North India. [PDF]

Indian Dermatol Online J
Kaur I, Williams A, John MJ, Alexander EE.   +3 more
europepmc   +1 more source