Results 221 to 230 of about 713,469 (335)

Tumour Cell Size Control and Its Impact on Tumour Cell Function

Cell Proliferation, EarlyView.
The regulatory mechanism of the size of tumour cells and its impact on the functions of tumour cells, as well as a summary of potential therapeutic targets for the corresponding mechanisms. ABSTRACT Cell size is an important component of cell morphological characteristics.
Min Zhou, Mei Zhou, Yang Jin
wiley   +1 more source

Isolated bone marrow gamma/delta T-cell lymphoma: A difficult case to classify according to the current WHO classification of lymphoid malignancies. [PDF]

Leuk Res Rep
Hyuuga H, Oishi N, Kumagai T, Matuura M, Nakadate A, Sakamoto Y, Suzuki J, Suzuki M, Koshiisi M, Kawashima I, Yamamoto T, Nakajima K, Tanaka M, Kondo T, Kirito K.   +14 more
europepmc   +1 more source

Genetic Basis of Acute Lymphoblastic Leukemia.

Journal of Clinical Oncology, 2017
I. Iacobucci, C. Mullighan
semanticscholar   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

European Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia.

New England Journal of Medicine, 2014
K. Roberts, Yongjin Li, D. Payne-Turner, R. Harvey, Yung‐Li Yang, Deqing Pei, K. McCastlain, L. Ding, Charles Lu, Guangchun Song, Jing Ma, J. Becksfort, Michael C. Rusch, Shann-Ching Chen, J. Easton, Jinjun Cheng, Kristy Boggs, Natalia Santiago-Morales, I. Iacobucci, R. Fulton, Ji-Rong Wen, M. Valentine, Cheng Cheng, S. Paugh, M. Devidas, I. Chen, S. Reshmi, Amy A. Smith, Erin K. Hedlund, P. Gupta, Panduka Nagahawatte, Gang Wu, Xiang Chen, D. Yergeau, Bhavin Vadodaria, H. Mulder, N. Winick, E. Larsen, W. Carroll, N. Heerema, A. Carroll, G. Grayson, S. Tasian, A. Moore, F. Keller, Melissa J. Frei-Jones, J. Whitlock, E. Raetz, D. White, T. Hughes, Jaime M Guidry Auvil, Malcolm A. Smith, G. Marcucci, C. Bloomfield, K. Mrózek, J. Kohlschmidt, W. Stock, S. Kornblau, M. Konopleva, E. Paietta, C. Pui, S. Jeha, M. Relling, W. Evans, D. Gerhard, J. Gastier-Foster, E. Mardis, R. Wilson, M. Loh, J. Downing, S. Hunger, C. Willman, Jinghui Zhang, C. Mullighan   +73 more
semanticscholar   +1 more source

Performance of Rapid Clonotyping of Chronic Lymphocytic Leukemia Using Flongle Flow‐Cell Nanopore Sequencing of IGH Rearrangements

European Journal of Haematology, EarlyView.
ABSTRACT Background Clonotyping of immunoglobulin heavy chain (IGH) gene rearrangements is critical for diagnosis, prognostication, and measurable residual disease monitoring in chronic lymphocytic leukemia (CLL). Although short‐read next‐generation sequencing (NGS) platforms, such as Illumina MiSeq, are widely used, they face challenges in spanning ...
Marcus Høy Hansen, Rona Gulmir, Oriane Cédile, Sara Kamuk Dahlmann, Sólja Remisdóttir Veyhe, Magnus Stougaard, Karen Juul‐Jensen, Charlotte Guldborg Nyvold   +7 more
wiley   +1 more source

Long-read sequencing unmasks a cryptic three-way translocation resulting in an ETV6::PDGFRB fusion. [PDF]

Mol Cytogenet
Tripodi J, Tremblay D, Ahire D, Najfeld V.   +3 more
europepmc   +1 more source

Serious Infections in Patients Receiving Ibrutinib for Treatment of Lymphoid Cancer

Clinical Infectious Diseases, 2018
Tilly A. Varughese, Y. Taur, Y. Taur, N. Cohen, M. Palomba, M. Palomba, S. Seo, Susan K. Seo, Tobias M. Hohl, Tobias M. Hohl, Gil Redelman-Sidi, Gil Redelman-Sidi   +11 more
semanticscholar   +1 more source

Bruton Tyrosine Kinase Inhibitors in Mantle Cell Lymphoma: What Are the Current Options?

European Journal of Haematology, EarlyView.
ABSTRACT Mantle Cell Lymphoma (MCL) is an aggressive B‐cell non‐Hodgkin lymphoma characterized by the hallmark t(11;14)(q13;q32) translocation, resulting in cyclin D1 overexpression. Predominantly affecting elderly males, MCL exhibits marked clinical and biological heterogeneity, ranging from indolent SOX11‐negative variants to highly proliferative ...
Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia

Proceedings of the National Academy of Sciences of the United States of America, 2012
C. Carmichael, D. Metcalf, K. J. Henley, Elizabeth A. Kruse, L. di Rago, S. Mifsud, W. Alexander, B. Kile   +7 more
semanticscholar   +1 more source