Results 221 to 230 of about 76,259 (245)
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Immunophenotyping of Chronic Lymphoid Leukemias
Journal of Clinical Oncology, 2008The 1983 article entitled “Chronic lymphocytic leukemia and other chronic lymphoid proliferations: surface marker phenotypes and clinical correlations,” which is reprinted in this issue of the Journal of Clinical Oncology, was one of the first reporting the use of monoclonal antibodies to expand the phenotypic characterization of chronic lymphoid ...
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Monoclonal antibodies in the treatment of lymphoid leukemia
Drugs of Today, 2003MoAb-based therapies are evolving into the first broad-spectrum class of targeted anti-leukemic therapy. Developments in many areas, including computer modeling of receptors and ligands, and increasing sophistication in recombinant technologies may result in a rapid increase in the number and complexity of MoAb available.
Susan O'Brien, Francis J. Giles
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INFECTION AND LYMPHOID LEUKEMIA
Journal of the American Medical Association, 1958To the Editor:— On Sept. 1, 1956, four children of a family developed diarrhea and vomiting. Three of them recovered after seven days. The fourth sibling continued having diarrhea and anorexia. About 14 days after this illness began, the mother noted that he was pale and that he had some bluish spots on the skin.
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Dynamic Morphology of Human Lymphoid Leukemias
1978In descriptions of scanning electron micrographs of normal and leukemic white blood cells, little thought has been given to the fact that surface morphology and shape are a function of cell motility and, thus, subject to frequent changes. Consideration of these facts necessitates the combination of scanning electron microscopy (SEM) with ...
H. Felix, G. Haemmerli, P. Strauli
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Lymphoid Leukemia in the Dog: Acute Lymphoblastic Leukemia and Chronic Lymphocytic Leukemia
Veterinary Clinics of North America: Small Animal Practice, 1985True lymphoid leukemia of bone-marrow origin may present as two distinct clinical forms in the dog. Acute lymphoblastic leukemia is a rapidly progressive disease associated with proliferation of malignant, undifferentiated lymphoblasts. Chronic lymphocytic leukemia is a more insidious form of malignancy associated with abnormal proliferation of small ...
Connie E. Leifer, Robert E. Matus
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IMMUNOLOGICAL STUDIES OF LYMPHOID LEUKEMIA IN THE AKR MOUSE
Canadian Journal of Biochemistry and Physiology, 1963Experiments are reported showing some slight protective capacity of guinea pig antimouse leukemic tissue serum to protect the AKR mouse against the BW5147 tumor, when the serum is first adsorbed to remove precipitating antibody for the tissue cell antigens.
Guthrie, R K+4 more
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Induction of apoptosis in lymphoid and myeloid leukemia
Current Oncology Reports, 2006Defects in the core machinery of the apoptosis pathway contribute to chemoresistance and poor outcomes in patients with acute leukemia. To overcome these defects, novel molecules that target key proteins in the apoptosis pathway are being developed. This review highlights compounds that target the mitochondrial, death receptor, and convergence pathways
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Lymphocyte membrane receptors in human lymphoid leukemias
European Journal of Immunology, 1975AbstractMembrane‐bound immunoglobulins, receptors for the Fc fragment of IgG and receptors for the third component of human or murine complement were used as B cell membrane markers to study eripheral blood lymphocytes from twentytwo patients with chronic lymphatic leukemia (CLL), five patients with acute lymphoblastic leukemia (ALL) and one patient ...
FERRARINI M+3 more
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Genomic analysis in lymphoid leukemias.
Reviews in clinical and experimental hematology, 2005The introduction of microarray analysis represents a revolution in the scientific field, allowing to investigate thousand of genes in a single experiment. Important biological insights have been revealed by this technique in several tumors: in acute lymphoblastic leukemia (ALL), these studies have allowed to identify specific patterns associated with ...
CHIARETTI, sabina, J. Ritz, FOA, Roberto
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Changes in the Treatment Landscape for Chronic Lymphoid Leukemia
New England Journal of Medicine, 2014After decades during which the treatment of patients with chronic lymphoid leukemia (CLL) was based on chemotherapy and more recently on chemoimmunotherapy, we are witnessing a new mechanism-driven era with the development of compounds capable of targeting the B-cell receptor signaling pathway.
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