Results 261 to 270 of about 895,463 (333)

Male breast cancer following complete remission of acute myeloid leukemia: A case report and literature review. [PDF]

Int J Surg Case Rep
Qiao W, Li P, Chang C, Fan M, Deng M.
europepmc   +1 more source

Chronic myeloid leukemia in India

Indian Journal of Medical and Paediatric Oncology, 2013
openaire   +4 more sources

Exploring Bioactive Metabolites From Fusarium falciforme and Aspergillus terreus Isolated From Protease‐Rich Fruits: Antifungal, Antitrypanosomal, and Enzymatic Inhibitory Activities

Chemistry &Biodiversity, EarlyView.
Metabolites from fungi isolated from protease rich‐fruits displayed antifungal, antitrypanosomal and enzymatic inhibitory activities. ABSTRACT Fungal secondary metabolites display remarkable chemical diversity and biological potential, with applications in agriculture and pharmaceuticals. This study isolated and characterized bioactive metabolites from
Gabriela de Oliveira Almeida, Vitor de Souza Mazucato, Ludmilla Tonani, Marcia Regina von Zeska Kress, Gisele Barbosa, Renata Krogh, Adriano Defini Andricopulo, Leonardo Luiz Gomes Ferreira, Paulo Cezar Vieira   +8 more
wiley   +1 more source

Synthesis, In Silico, and Biological Evaluation of Non‐Hydroxamate Benzoic Acid–Based Derivatives as Potential Histone Deacetylase Inhibitors (HDACi)

Chemistry &Biodiversity, EarlyView.
Compound A3bn exhibited strong binding affinities for HDAC2, HDAC6, and HDAC8. A3bn’s anticancer IC50 values were similar to those of SAHA. Cell death resulted from the extrinsic apoptotic pathway. Compound A3bn, a hydrophilic linker, which promotes zinc coordination, may be the cause of its increased activity across HDAC isoforms. ABSTRACT Unregulated
Nedaa A. Abd Al Rahim, Ammar A. Razzak Mahmood, Lubna H. Tahtamouni, Randa M. Bawadi, Ayah Y. Almasri, Marya A. Hamad, Nour A. Hussein, Salem R. Yasin, Abdulrahman M. Saleh   +8 more
wiley   +1 more source

CALR Type 1‐Like Mutations Increase Endoplasmic Reticulum Free Ca2+ and Induce ERK1/2 Activation Independent of Thrombopoietin Receptor Activation

Cell Biology International, EarlyView.
ABSTRACT Calreticulin is a multifunctional protein found in the endoplasmic reticulum lumen that is important for calcium homeostasis and glycoprotein folding. Mutations in exon 9 of the CALR gene are the second most common genetic cause of myeloproliferative neoplasms.
Mifra Faiz, Caitlin Dunstan‐Harrison, Elizabeth C. Ledgerwood   +2 more
wiley   +1 more source

Acute Myeloid Leukemia: Updates on Diagnosis, Treatment and Management. [PDF]

Cancers (Basel)
Lanza F, Rondoni M, Marconi G.
europepmc   +1 more source

Anisotropic Nuclear Magnetic Resonance Spectroscopy and Density Functional Theory Methodologies Combine with CASE‐3D Analysis for Unambiguous Diastereomeric Differentiation of AMG 176 Macrocycles

ChemistryEurope, EarlyView.
CASE‐3D Nuclear magnetic resonance (NMR) analysis is shown to be robust for unambiguous diastereomeric differentiation of the flexible AMG 176 molecules, utilizing both isotropic and anisotropic NMR parameters. The large conformational space of the macrocyclic AMG 176 diastereomers is pruned down through a stepwise DFT conformer filtering and ...
Ikenna Edward Ndukwe, Maria Victoria Silva Elipe, Kyle Quasdorf, Armando Navarro‐Vázquez, Narbe Mardirossian, David Khachatrian, Philipp C. Roosen, Austin Smith   +7 more
wiley   +1 more source

Acute Promyelocytic Leukemia in a Patient With Sickle Cell Hemoglobin D Disease: A Case Report. [PDF]

Cureus
Bokhary M, Turak E, Ibrahim R, Rashed A, Abdelhadi M, Ozturk C, Sudha S, Kaynar L, Fadel E.   +8 more
europepmc   +1 more source

A Poly (β‐Amino Esters)‐Based Multicomponent Nanoparticle for Efficient mRNA Delivery to Acute Myeloid Leukemia Cells

ChemistryEurope, EarlyView.
A structurally engineered nonviral vector (poly (β‐amino esters)‐lipid‐palmitic anhydride nanoparticles) integrates a poly(β‐amino ester) core for mRNA binding, palmitic anhydride for enhancing cellular uptake, and cationic 1,2‐Dioleoyl‐3‐trimethylammonium‐propane lipid for endosomal disruption is developed, which achieves 64.4% transfection efficiency
Zheng Wang, Dehua Huang, Lanrong Wu, Yuheng Cao, Yejun Zhang, Chunyan Li, Jiang Jiang, Guangcun Chen, Qiangbin Wang   +8 more
wiley   +1 more source