Results 61 to 70 of about 961,470 (198)

Bortezomib-based Regimens Improve the Outcome of Patients with Primary or Secondary Plasma Cell Leukemia: A Retrospective Cohort Study

Turkish Journal of Hematology, 2020
Objective: The management experience for plasma cell leukemia (PCL) is still limited by PCL's rare incidence and aggressive course. The goal of this study was to further identify the efficacy of bortezomibcontaining regimens for PCL in Chinese patients.
Huijuan Wang, Huixing Zhou, Zhiyao Zhang, Chuanying Geng, Wenming Chen   +4 more
doaj   +1 more source

Case study: Acute plasmoblastic leukemia presentation following effective haploidentical hematopoietic stem cell transplantation therapy

Journal of International Medical Research
Plasma cell leukemia is a rare and aggressive malignancy characterized by monoclonal gammopathy and the presence of circulating plasma cells in the peripheral blood.
Azat Karabekov, Madina Abdirgalieva, Aigerim Najipova, Vadim Kemaykin, Olga Kolesnikova, Ruzal Vildanova, Almira Manatova, Zhuldyz Kuanysh   +7 more
doaj   +1 more source

Effect of cold atmospheric plasma treatment on the metabolites of human leukemia cells

Cancer Cell International, 2019
Background Acute myeloid leukemia (AML) is a typically fatal malignancy and new drug and treatment need to be developed for a better survival outcome.
Dehui Xu, Ning Ning, Yujing Xu, Bingchuan Wang, Qingjie Cui, Zhijie Liu, Xiaohua Wang, Dingxin Liu, Hailan Chen, Michael G. Kong   +9 more
doaj   +1 more source

PLASMA CELL LEUKEMIA

Leukemia, 2012
Plasma cell leukemia (PCL) is a rare and aggressive variant of myeloma characterized by the presence of circulating plasma cells. It is classified as either primary PCL occurring at diagnosis or as secondary PCL in patients with relapsed/refractory ...
C. F. de Larrea, R. Kyle, B. Durie, H. Ludwig, S. Usmani, D. Vesole, R. Hájek, J. Miguel, Orhan Sezer, P. Sonneveld, Shaji K. Kumar, A. Mahindra, R. Comenzo, A. Palumbo, Amitabha Mazumber, K. Anderson, P. Richardson, A. Badros, J. Caers, M. Cavo, X. Leleu, M. Dimopoulos, C. Chim, R. Schots, Amara Noeul, D. Fantl, U. Mellqvist, O. Landgren, A. Chanan-Khan, P. Moreau, R. Fonseca, G. Merlini, J. Lahuerta, J. Bladé, R. Orlowski, J. Shah   +35 more
semanticscholar   +1 more source

EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation

Leukemia, 2019
Plasma cells (PCs) play a major role in the defense of the host organism against pathogens. We have shown that PC generation can be modeled using multi-step culture systems that reproduce the sequential cell differentiation occurring in vivo.
Laurie Herviou, M. Jourdan, Anne-Marie Martinez, G. Cavalli, J. Moreaux   +4 more
semanticscholar   +1 more source

Oral Tumor Revealing Primary Plasma-cell Leukemia

Balkan Medical Journal, 2021
Maryame Ahnach, Houda Youssefi, Mounia Bendari   +2 more
doaj   +1 more source

Case of angioimmunoblastic T-cell lymphoma presenting as peripheral and bone marrow plasmacytosis: A diagnostic conundrum

Indian Journal of Pathology and Microbiology
Angioimmunoblastic T-cell lymphoma (AITL), a subtype of peripheral T-cell lymphoma (PTCL), is associated with unique clinical, morphological, and immunohistochemical features.
Deepika Gupta, Nagarjun S. Jaine, Sandeep K. Bairwa, Balamurugan Thirunavukkarasu, Vikarn Vishwajeet, Abhishek H. L. Purohit   +5 more
doaj   +1 more source

Primary plasma cell leukemia: clinical and laboratory presentation, gene-expression profiling, and clinical outcome with Total Therapy protocols

Leukemia, 2012
To determine whether primary plasma cell leukemia (PPCL) remains a high-risk multiple myeloma feature in the context of contemporary therapy and gene-expression profiling (GEP), we reviewed records of 1474 patients with myeloma, who were enrolled in ...
S. Usmani, B. Nair, P. Qu, E. Hansen, Qing Zhang, N. Petty, S. Waheed, J. Shaughnessy, Y. Alsayed, C. Heuck, F. van Rhee, Teresa Milner, A. Hoering, J. Szymonifka, R. Sexton, J. Sawyer, Z. Singh, J. Crowley, B. Barlogie   +18 more
semanticscholar   +1 more source

Overexpression of chitinase like protein YKL-40 in leukemia patients [PDF]

Journal of BioScience and Biotechnology, 2013
YKL-40 is a member of mammalian chitanase (CHI3L1), expressed and secreted by several types of solid tumor cells, inflammatory cells and stem cells. The precise physiological role of YKL-40 in cancer is still not clear and it is suggested that it play a ...
Anil K. Hurmale, Sudheer K. Choudhary, Satish K. Bhaskar, Suresh K. Jatawa, Mahavir Yadav, Archana Tiwari   +5 more
doaj  

Estimation of plasma concentrations of hepatocyte growth factor in acute leukemia in Upper Egypt

Egyptian Pediatric Association Gazette, 2015
Background: Angiogenesis is a fundamental element during malignant transformation, the induction of angiogenesis has been proposed to be through angiogenic factors such as the hepatocyte growth factor (HGF). Aim: The aim of the study was to assess plasma
Ahmed E. Ahmed, Khalid A. Abd El-Baser, Sameh S. Zytoun, Mohammed A. Alsenbesy, Abd-Elrahman A. Elsaid   +4 more
doaj   +1 more source