Effect of Nanoparticle Rigidity on the Interaction of Stromal Membrane Particles with Leukemia Cells
Advanced Healthcare Materials, EarlyView.Cell membrane nanoparticles made with stromal cells are prepared and used to target leukemia cells. Deposition of the cell membrane onto rigid silica cores leads to increased uptake both in leukemia cell lines and primary cells from patients. These results show that nanoparticle rigidity affects the interaction between cell membrane nanoparticles and ...
Sander de Weerd +8 more
wiley +1 more source
Ethnic Differences in the Incidence of Leukemia [PDF]
, 1957 Brian MacMahon, Ernest K. Koller
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Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro
Advanced Healthcare Materials, EarlyView.A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski +3 more
wiley +1 more source
CLINICAL APPLICABILITY OF PROPOSED ALGORITHM FOR IDENTIFYING INDIVIDUALS AT RISK FOR HEREDITARY HEMATOLOGIC MALIGNANCIES [PDF]
, 2017 Over the past decade, more than 12 genes have been identified to cause hereditary predispositions to hematologic malignancies. These syndromes are characterized by an increased risk to develop myelodysplastic syndrome (MDS), acute myeloid leukemia (AML),
Clifford, Maggie
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IMMUNOLOGICAL RELATIONSHIPS OF A FILTERABLE AGENT CAUSING A LEUKEMIA IN ADULT MICE [PDF]
, 1959 Charlotte Friend
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Advanced Healthcare Materials, EarlyView.This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail +3 more
wiley +1 more source
Sulindac sulfide reverses aberrant self-renewal of progenitor cells induced by the AML-associated fusion proteins PML/RARalpha and PLZF/RARalpha [PDF]
, 2011 Chromosomal translocations can lead to the formation of chimeric genes encoding fusion proteins such as PML/RARalpha, PLZF/RARalpha, and AML-1/ETO, which are able to induce and maintain acute myeloid leukemia (AML). One key mechanism in leukemogenesis is
Hagemeyer, Heike +6 more
core
ELECTROPHORETIC STUDIES OF THE VITAMIN B12-BINDING PROTEIN OF NORMAL AND CHRONIC MYELOGENOUS LEUKEMIA SERUM* [PDF]
, 1959 Aaron Miller, John Sullivan
openalex +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source