Results 131 to 140 of about 809,322 (319)

Successful Long-Term Remission in Infantile Acute Leukemia Treated With Chemotherapy and Blinatumomab: A Case Report. [PDF]

Am J Case Rep
He Q, Zhang B, Li S, Yang J, Hao L.
europepmc   +1 more source

Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy

Advanced Science, EarlyView.
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo, Haixiao Zhang, Kaiting Tang, Yiming Wang, Huajiang Dong, Wei Qi, Lingling Shan, Yue Tan, Liping Zhao, Jun Shi, Erlie Jiang, Jing Pan, Xiaoming Feng   +12 more
wiley   +1 more source

The contribution of the membrane-bound complement regulatory proteins CD46 and CD55 in phases of acute lymphocytic leukemia and acute myelogenous leukemia. [PDF]

Sci Rep
Onsi LA, Ammar P, Abdelaziz H, Abou-Aisha K, Farag N, El-Azizi M.   +5 more
europepmc   +1 more source

Myeloid Sarcoma of the Paranasal Sinuses in a Patient with Acute Myeloid Leukemia

, 2018
Jun Suzuki, Yoriko Harazaki, Shinkichi Morita, Yoshiko Kaga, Kazuhiro Nomura, Mitsuru Sugawara, Yukio Katori   +6 more
openalex   +2 more sources

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Karyotype evolution and acquisition of FLT3 or RAS pathway alterations drive progression of myelodysplastic syndrome to acute myeloid leukemia

Haematologica, 2015
Manja Meggendorfer, Andreia de Albuquerque, Niroshan Nadarajah, Tamara Alpermann, Wolfgang Kern, Kimberly Steuer, Karolína Perglerová, Claudia Haferlach, Susanne Schnittger, Torsten Haferlach   +9 more
doaj   +1 more source

Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity

Advanced Science, EarlyView.
Proinflammatory mast cells represent an MHC‐IIhigh, cytokine‐producing mast cell subset associated with improved survival and enhanced responses to anti‐PD‐1 therapy. Retinoic acid drives their polarization, enabling antigen uptake and presentation, and T cell recruitment and activation, collectively promoting adaptive anti‐tumor immunity.
Lizao Zhang, Siqi Ren, Yuhui Li, Rongxi Chen, Ling Qiu, Yongmei Tan, Suling Chen, Huiqian Wu, Lianxi Mai, Xiao Tan, Xin Liu, Peisheng Liang, Shijia Kuang, Liansheng Wang, Jingkang Liu, Jintao Li, Yanyan Li, Qiuping Xu, Yongzhi Su, Yuehai Luo, Binyan Wu, Zijing Huang, Haotian Cao, Qunxing Li, Jinsong Li, Tianjun Lan   +25 more
wiley   +1 more source

Molecular genetic characterization of myeloid/lymphoid neoplasms associated with eosinophilia and rearrangement of PDGFRA, PDGFRB, FGFR1 or PCM1-JAK2

Haematologica, 2018
Constance Baer, Verena Muehlbacher, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach   +4 more
doaj   +1 more source

Clonal Evolution and Lineage Switch from T-Cell Acute Lymphoblastic Leukemia to Acute Myeloid Leukemia in Therapy-Resistant <i>PICALM::MLLT10</i> Leukemia. [PDF]

EJHaem
Kawamura M, Sadato D, Haruta M, Kubota N, Harada Y, Kobayashi T, Doki N, Kasai F, Nishimura Y, Kobayashi H, Maseki N.   +10 more
europepmc   +1 more source

Induction of apoptosis and differentiation by Na/H exchanger 1 modulation in acute myeloid leukemia cells

, 2019
Shin Young Hyun, Eun Jung Na, Ji Eun Jang, Haerim Chung, Soo‐Jeong Kim, Jin Seok Kim, Jee Hyun Kong, Kwang Yong Shim, Jong In Lee, Yoo Hong Min, June‐Won Cheong   +10 more
openalex   +2 more sources