Results 181 to 190 of about 1,123,126 (369)

Metaphase and Interphase Cytogenetics with Alu-PCR-amplified Yeast Artificial Chromosome Clones Containing the BCR Gene and the Protooncogenes c-raf-1, c-fms, and c-erbB-21 [PDF]

, 1992
A human yeast artificial chromosome (YAC) library was screened by polymerase chain reaction with oligonucleotide primers defined for DNA sequences of the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erB-2.
Becher, Reinhard, Cremer, Thomas, Green, Eric D., Konecki, David, Lengauer, Christoph, Olson, Maynard V., Riethman, Harold C., Speicher, Michael R., Taniwaki, Masafumi   +8 more
core  

The Super Enhancer‐Driven Long Noncoding RNA PRKCQ‐AS1 Promotes Neuroblastoma Tumorigenesis by Interacting With MSI2 Protein and Is Targetable by Small Molecule Compounds

Advanced Science, EarlyView.
PRKCQ‐AS1 is overexpressed due to transcriptional super‐enhancers. PRKCQ‐AS1 RNA forms a complex with MSI2 protein to induce BMX mRNA stabilization and overexpression, ERK protein phosphorylation and neuroblastoma cell proliferation. Compound NSC617570 blocks PRKCQ‐AS1 binding to MSI2, leading to BMX mRNA disassociation from MSI2 protein, BMX reduction,
Sujanna Mondal, Pei Y. Liu, Janith Seneviratne, Antoine De Weck, Pooja Venkat, Chelsea Mayoh, Jing Wu, Jesper Maag, Jingwei Chen, Matthew Wong, Nenad Bartonicek, Poh Khoo, Lei Jin, Louise E. Ludlow, David S. Ziegler, Toby Trahair, Pieter Mestdagh, Belamy B. Cheung, Jinyan Li, Marcel E. Dinger, Ian Street, Xu D. Zhang, Glenn M. Marshall, Tao Liu   +23 more
wiley   +1 more source

Specific molecular mutation patterns delineate chronic neutrophilic leukemia, atypical chronic myeloid leukemia, and chronic myelomonocytic leukemia

Haematologica, 2014
Manja Meggendorfer, Torsten Haferlach, Tamara Alpermann, Sabine Jeromin, Claudia Haferlach, Wolfgang Kern, Susanne Schnittger   +6 more
doaj   +1 more source

Molecular characterization of acute myeloid leukemia patients who relapse more than 3 years after diagnosis: an exome sequencing study of 31 patients

Haematologica, 2020
Luise Hartmann, Claudia Haferlach, Manja Meggendorfer, Niroshan Nadarajah, Wolfgang Kern, Torsten Haferlach, Anna Stengel   +6 more
doaj   +1 more source

P769: MUTATION PROFILES AND RISK STRATIFICATION IN HYPOCELLULAR MYELODYSPLASTIC SYNDROME

HemaSphere, 2022
K. Kim, K. Chien, O. Faustine, G. Montalban-Bravo, R. Kanagal-Shamanna, T. Kadia, E. Jabbour, Y. Alvarado, K. Sasaki, X. Q. Dong, S. Pierce, C. Bueso-Ramos, H. Kantarjian, G. Garcia-Manero   +13 more
doaj   +1 more source

Trends of Mortality from Leukemia in the United States, 1921-55 [PDF]

, 1958
Alexander G. Gilliam, William Walter
openalex   +1 more source

Advancing Allogeneic NK Cell Immunotherapy through Microfluidic Gene Delivery

Advanced Science, EarlyView.
The Y‐Hydroporator is a microfluidic gene delivery platform designed for allogeneic NK cell‐based immunotherapies. It achieves highly efficient gene delivery while preserving high cell viability and functionality. By producing engineered NK cells with enhanced cytotoxicity, the platform addresses critical limitations of autologous cell therapy ...
Hyelee Kim, Mujin Lee, Bohwa Han, Jinho Kim, Duck Cho, Junsang Doh, Aram J. Chung   +6 more
wiley   +1 more source

Granular B lymphoblastic leukemia

, 2023
American Journal of Hematology, Volume 98, Issue 1, Page 210-211, January 2023.
Biswadip Hazarika, Barbara J. Bain
wiley   +1 more source

P754: INITIAL RESULTS OF PHASE I/II STUDY OF AZACITIDINE IN COMBINATION WITH QUIZARTINIB FOR PATIENTS WITH MYELODYSPLASTIC SYNDROME AND MYELODYSPLASTIC/MYELOPROLIFERATIVE NEOPLASM WITH FLT3 OR CBL MUTATION

HemaSphere, 2022
T. Abuasab, E. Jabbour, N. Short, M. Konopleva, K. S. Chien, S. Fareed Mohamed, N. Daver, R. Kanagal-shamanna, G. Garcia-Manero, G. Montalban-Bravo   +9 more
doaj   +1 more source

Probing leukemia cells behavior under starvation [PDF]

arXiv
The ability of a cancer cell population to achieve heterogeneity in their phenotype distributions offers advantages in tumor invasiveness and drug resistance. Studying the mechanisms behind such observed heterogeneity in mammalian cells presents challenges due for instance to the prolonged proliferation times compared to widely studied unicellular ...
arxiv