Results 191 to 200 of about 1,742,061 (410)

Serum Polysaccharide and Fever in Thrombocytopenic Bleeding of Leukemia [PDF]

, 1954
GUSTAVE FREEMAN, EDWARD S. BUCKLEY
openalex   +1 more source

Targeting BCL2 with Venetoclax in Relapsed Chronic Lymphocytic Leukemia.

New England Journal of Medicine, 2016
A. Roberts, M. Davids, J. Pagel, B. Kahl, S. Puvvada, J. Gerecitano, T. Kipps, M. Anderson, Jennifer R. Brown, Lori A. Gressick, S. Wong, M. Dunbar, Ming Zhu, Monali Desai, E. Cerri, Sari Heitner Enschede, R. Humerickhouse, W. Wierda, J. Seymour   +18 more
semanticscholar   +1 more source

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Refractory anemia with ring sideroblasts and marked thrombocytosis cases harbor mutations in SF3B1 or other spliceosome genes accompanied by JAK2V617F and ASXL1 mutations

Haematologica, 2015
Sabine Jeromin, Torsten Haferlach, Sandra Weissmann, Manja Meggendorfer, Christiane Eder, Niroshan Nadarajah, Tamara Alpermann, Alexander Kohlmann, Wolfgang Kern, Claudia Haferlach, Susanne Schnittger   +10 more
doaj   +1 more source

Polycythemia Vera Terminating with Myeloblastic Leukemia [PDF]

, 1954
Marjorie J. Williams, Julius L. Mendel
openalex   +1 more source

Branched‐Chain α Keto‐Acid Dehydrogenase Kinase‐Mediated AKT Phosphorylation Promotes RCC Tumorigenesis and Drug Resistance

Advanced Science, EarlyView.
This study identifies a novel oncogenic role and a previously unrecognized phosphorylation substrate of BCKDK in RCC, wherein it promotes tumor progression and drug resistance through AKT phosphorylation at both Thr308 and Ser473 sites and activation of AKT/mTOR and AKT/ABCB1 signaling pathways, offering a promising prognostic marker and therapeutic ...
Qin Tian, Jinxiang Wang, Qiji Li, Yangruiyu Liu, Yanping Chen, Jiacheng Feng, Zi‐Ning Lei, Harsh Patel, Chao‐Yun Cai, Yuzhi Xu, Chuntao Quan, Lingyan Fei, Zexiu Xiao, Shuo Fang, Tianxin Lin, Zhe‐Sheng Chen, Yuchen Liu, Leli Zeng, Yihang Pan   +18 more
wiley   +1 more source

P566: IMPACT OF FRONTLINE INDUCTION APPROACH ON POST-STEM CELL TRANSPLANT (SCT) OUTCOMES IN OLDER ADULTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA (AML)

HemaSphere, 2022
F. Ong, F. Ravandi, U. Popat, T. M. Kadia, N. Daver, C. DiNardo, M. Konopleva, G. Borthakur, E. J. Shpall, B. Oran, G. Al-Atrash, R. Mehta, E. J. Jabbour, M. Yilmaz, G. C. Issa, G. Garcia-Manero, A. Maiti, H. A. Abbas, R. E. Champlin, N. J. Short   +19 more
doaj   +1 more source

Radioactive phosphorus. II. In the treatment of myeloid leukemia [PDF]

, 1951
Henry D. Diamond, Lloyd F. Craver
openalex   +1 more source

Analysis of global, regional, and national burden and attributable risk factors of acute lymphoblastic leukemia and acute myeloid leukemia from 1990 to 2021. [PDF]

PLoS One
Ni H, Shi Y, Wang M, Ji C.
europepmc   +1 more source

Acod1 Promotes PAD4 Ubiquitination via UBR5 Alkylation to Modulate NETosis and Exert Protective Effects in Sepsis

Advanced Science, EarlyView.
In this study, Acod1 knockout in CLP mice significantly increases peripheral blood NET levels, exacerbating inflammation, organ damage, and reducing survival. Further research shows that UBR5 interacts with PAD4, a key NET formation protein. Acod1/itaconate (ITA) enhances the enzymatic activity of UBR5 by alkylating the Cys2768 site, promoting the K48 ...
Huifan Liu, Guoqing Jing, Shujuan Wu, Min Yuan, Yingyue Dong, Xue Chen, Huimin Zhou, Hailong Gong, Jing Zuo, Xiaojing Wu, Xuemin Song   +10 more
wiley   +1 more source